Novel coordination of lipopolysaccharide modifications in Vibrio cholerae promotes CAMP resistance.

abstract：:Escherichia coli and Salmonella can use chitin-derived oligosaccharides as carbon and nitrogen sources. Chitosugars traverse the outer membrane through a dedicated chitoporin, ChiP, and are transported across the cytoplasmic membrane by the chitobiose transporter (ChbBCA). Previous work revealed that synthesis of the ...

journal_title：Molecular microbiology

authors： Plumbridge J,Bossi L,Oberto J,Wade JT,Figueroa-Bossi N

更新日期：2014-05-01 00:00:00

abstract：:MsDef1 and MtDef4 from Medicago spp. are small cysteine-rich defensins with potent antifungal activity against a broad range of filamentous fungi. Each defensin has a hallmark γ-core motif (GXCX(3-9) C), which contains major determinants of its antifungal activity. In this study, the antifungal activities of MsDef1, M...

journal_title：Molecular microbiology

authors： Muñoz A,Chu M,Marris PI,Sagaram US,Kaur J,Shah DM,Read ND

更新日期：2014-06-01 00:00:00

abstract：:Sinorhizobium meliloti, the endosymbiont of Medicago sativa, can use haem compounds, including haemoglobin and leghaemoglobin, when growing in the free-living state. The components of the system involved in haem acquisition were confirmed to be ShmR, an outer membrane receptor, and HmuTUV, predicted to be an ABC trans...

journal_title：Molecular microbiology

authors： Cuív PO,Keogh D,Clarke P,O'Connell M

更新日期：2008-12-01 00:00:00

abstract：:Gut bacteria recognize accessible glycan substrates within a complex environment. Carbohydrate binding modules (CBMs) of cell surface glycoside hydrolases often drive binding to the target substrate. Eubacterium rectale, an important butyrate-producing organism in the gut, consumes a limited range of substrates, inclu...

journal_title：Molecular microbiology

authors： Cockburn DW,Suh C,Medina KP,Duvall RM,Wawrzak Z,Henrissat B,Koropatkin NM

更新日期：2018-01-01 00:00:00

abstract：:The Escherichia coli rodA and ftsW genes and the spoVE gene of Bacillus subtilis encode membrane proteins that control peptidoglycan synthesis during cellular elongation, division and sporulation respectively. While rodA and ftsW are essential genes in E. coli, the B. subtilis spoVE gene is dispensable for growth and ...

journal_title：Molecular microbiology

authors： Henriques AO,Glaser P,Piggot PJ,Moran CP Jr

更新日期：1998-04-01 00:00:00

abstract：:The FNR protein in Escherichia coli is an O(2) sensor that modifies global gene expression to adapt the cell to anaerobic growth. Regulation of FNR involves continuous cycling of the protein between its active and inactive states under aerobic conditions without apparent function. This raises the question of what bene...

journal_title：Molecular microbiology

authors： Tolla DA,Savageau MA

更新日期：2011-01-01 00:00:00

abstract：:A two-hybrid approach was applied to screen for proteins with the ability to interact with PHB synthase (PhaC1) of Ralstonia eutropha. The H16_A0141 gene (phaM) was identified in the majority of positive clones. PhaM (26.6 kDa) strongly interacted with PhaC1 and with phasin PhaP5 but not with PhaP1 or other PHB granul...

journal_title：Molecular microbiology

authors： Pfeiffer D,Wahl A,Jendrossek D

更新日期：2011-11-01 00:00:00

abstract：:Bacterial cytokinesis is driven by the septal ring apparatus, the assembly of which in Escherichia coli is directed to mid-cell by the Min system. Despite suffering aberrant divisions at the poles, cells lacking the minCDE operon (Min(-)) have an almost normal growth rate. We developed a generally applicable screening...

journal_title：Molecular microbiology

authors： Bernhardt TG,de Boer PA

更新日期：2004-06-01 00:00:00

abstract：:We isolated and characterized three spontaneous mutations leading to trimethylamine N-oxide (TMAO)-independent expression of the tor operon encoding the TMAO-reductase anaerobic respiratory system in Escherichia coli. The mutations lie in a new for regulatory gene, the torS gene, which probably encodes a sensor protei...

journal_title：Molecular microbiology

authors： Jourlin C,Bengrine A,Chippaux M,Méjean V

更新日期：1996-06-01 00:00:00

abstract：:Cyclic di-GMP (c-di-GMP) controls the transition between sessility and motility in many bacterial species. This regulation is achieved by a variety of mechanisms including alteration of transcription initiation and inhibition of flagellar function. How c-di-GMP inhibits the motility of Vibrio cholerae has not been det...

journal_title：Molecular microbiology

authors： Srivastava D,Hsieh ML,Khataokar A,Neiditch MB,Waters CM

更新日期：2013-12-01 00:00:00

abstract：:Cytoadhesion of infected red blood cells (iRBC) is mediated through parasite-encoded, clonally variant surface antigens (VSA) and is a central process in the pathogenesis of Plasmodium falciparum malaria. Pregnancy-associated malaria (PAM) has been linked to VSA-mediated adhesion of iRBC to the glycosaminoglycan chond...

journal_title：Molecular microbiology

authors： Salanti A,Staalsoe T,Lavstsen T,Jensen AT,Sowa MP,Arnot DE,Hviid L,Theander TG

更新日期：2003-07-01 00:00:00

abstract：:We report the cloning and determination of the nucleotide sequence of the gene encoding nucleoside diphosphate kinase (Ndk) from Pseudomonas aeruginosa. The amino acid sequence of Ndk was highly homologous with other known bacterial and eukaryotic Ndks (39.9 to 58.3% amino acid identity). We have previously reported t...

journal_title：Molecular microbiology

authors： Sundin GW,Shankar S,Chugani SA,Chopade BA,Kavanaugh-Black A,Chakrabarty AM

更新日期：1996-06-01 00:00:00

abstract：:Trans-acting small regulatory RNAs (sRNAs) are key players in the regulation of gene expression in bacteria. There are hundreds of different sRNAs in a typical bacterium, which in contrast to eukaryotic microRNAs are more heterogeneous in length, sequence composition, and secondary structure. The vast majority of sRNA...

journal_title：Molecular microbiology

authors： Georg J,Lalaouna D,Hou S,Lott SC,Caldelari I,Marzi S,Hess WR,Romby P

更新日期：2020-03-01 00:00:00

abstract：:In this issue of Molecular Microbiology, Rugarabamu and colleagues investigate the role of rhomboid proteases responsible for adhesin shedding during invasion of the apicomplexan parasite Toxoplasma gondii. This study, together with several other recent publications, raises new questions about the function of these rh...

journal_title：Molecular microbiology

authors： Stewart RJ,Tonkin CJ

更新日期：2015-07-01 00:00:00

abstract：:In response to recommendations from the Steering Committees responsible for co-ordination of World Health Organization programmes for research on the immunology of leprosy (IMMLEP) and tuberculosis (IMMTUB), a list was prepared summarizing the properties of mycobacterial proteins currently under investigation with res...

journal_title：Molecular microbiology

authors： Young DB,Kaufmann SH,Hermans PW,Thole JE

更新日期：1992-01-01 00:00:00

abstract：:It has been hypothesized that the dinR gene product of Bacillus subtilis acts as a repressor of the SOS regulon by binding to DNA sequences located upstream of SOS genes, including dinR and recA. Following activation as a result of DNA damage, RecA is believed to catalyse DinR-autocleavage, thus derepressing the SOS r...

journal_title：Molecular microbiology

authors： Haijema BJ,van Sinderen D,Winterling K,Kooistra J,Venema G,Hamoen LW

更新日期：1996-10-01 00:00:00

abstract：:Candida albicans is an opportunistic fungal pathogen. In immunocompromised individuals, it can cause bloodstream infections with high mortality rates. The ability to switch between yeast and hyphal morphologies is a critical virulence factor of C. albicans. In response to diverse environmental cues, several signaling ...

journal_title：Molecular microbiology

authors： Chen C,Zeng G,Wang Y

更新日期：2018-10-01 00:00:00

abstract：:Aspergillus fumigatus, an important human nosocomial pathogen, is resistant to sordarin derivatives, a new family of antifungals that inhibit protein synthesis by interaction with the EF-2-ribosomal stalk complex. To explore the role of the A. fumigatus ribosome in the resistance mechanism, the fungal stalk proteins w...

journal_title：Molecular microbiology

authors： Santos C,Ballesta JP

更新日期：2002-01-01 00:00:00

abstract：:The haemolytic activity of Serratia marcescens is determined by two proteins, ShlA and ShlB. ShlA integrates into the erythrocyte membrane and causes osmotic lysis through channel formation. The conformation of ShlA and its interaction with erythrocyte membranes were studied by determining the cleavage of ShlA by adde...

journal_title：Molecular microbiology

authors： Schiebel E,Braun V

更新日期：1989-03-01 00:00:00

abstract：:Glutathione (GSH) is an abundant low-molecular-mass thiol which has been implicated in numerous cellular processes including protection against cytotoxic agents such as xenobiotics, carcinogens and free radicals. Utilization of GSH results in its conversion to the oxidized form (GSSG), and it is recycled to GSH by the...

journal_title：Molecular microbiology

authors： Grant CM,Maciver FH,Dawes IW

更新日期：1996-11-01 00:00:00

abstract：:Dimerization and inactivation of ribosomes in Escherichia coli is a two-step process that involves the binding of ribosome modulation factor (RMF) and hibernation promotion factor (HPF). Lactococcus lactis MG1363 expresses a protein, YfiA(L) (l) , which associates with ribosomes in the stationary phase of growth and i...

journal_title：Molecular microbiology

authors： Puri P,Eckhardt TH,Franken LE,Fusetti F,Stuart MC,Boekema EJ,Kuipers OP,Kok J,Poolman B

更新日期：2014-01-01 00:00:00

abstract：:Cellulosomes are key for lignocellulosic biomass degradation in cellulolytic Clostridia. Better understanding of the mechanism of cellulosome regulation would allow us to improve lignocellulose hydrolysis. It is hypothesized that cellulosomal protease inhibitors would regulate cellulosome architecture and then lignoce...

journal_title：Molecular microbiology

authors： Xu T,Li Y,He Z,Zhou J

更新日期：2014-02-01 00:00:00

abstract：:Mycobacterium smegmatis mc2 155 has three genes (MSMEG_6383, furA1; MSMEG_3460, furA2; MSMEG_6253, furA3) encoding FurA (ferric-uptake regulator A) paralogs. Three FurA paralogs in M. smegmatis are functionally redundant and negatively regulate expression of a subset of genes involved in peroxide detoxification such a...

journal_title：Molecular microbiology

authors： Lee HN,Ji CJ,Lee HH,Park J,Seo YS,Lee JW,Oh JI

更新日期：2018-06-01 00:00:00

abstract：:In cyanobacteria and chloroplasts, exposure to HL damages the photosynthetic apparatus, especially the D1 subunit of Photosystem II. To avoid chronic photoinhibition, a PSII repair cycle operates to replace damaged PSII subunits with newly synthesised versions. To determine the sub-cellular location of this process, w...

journal_title：Molecular microbiology

authors： Sacharz J,Bryan SJ,Yu J,Burroughs NJ,Spence EM,Nixon PJ,Mullineaux CW

更新日期：2015-05-01 00:00:00

abstract：:The DNA of wild-type Streptomyces lividans 66 is degraded during electrophoresis in buffers containing traces of ferrous iron. S. lividans ZX1, a mutant selected for resistance to DNA degradation, simultaneously became sensitive to phi HAU3, a wide-host-range temperate bacteriophage. A DNA fragment conferring phi HAU3...

journal_title：Molecular microbiology

authors： Zhou X,Deng Z,Hopwood DA,Kieser T

更新日期：1994-06-01 00:00:00

abstract：:The evolutionary relationship within prokaryotes is examined based on signature sequences (defined as conserved inserts or deletions shared by specific taxa) and phylogenies derived from different proteins. Archaebacteria are indicated as being monophyletic by a number of proteins related to the information transfer p...

journal_title：Molecular microbiology

authors： Gupta RS

更新日期：1998-08-01 00:00:00

abstract：:The bacterial RNA-binding protein Hfq functions in post-transcriptional regulation of gene expression. There is evidence in a range of bacteria for specific subcellular localization of Hfq; however, the mechanism and role of Hfq localization remain unclear. Cyanobacteria harbour a subfamily of Hfq that is structurally...

journal_title：Molecular microbiology

authors： Schuergers N,Ruppert U,Watanabe S,Nürnberg DJ,Lochnit G,Dienst D,Mullineaux CW,Wilde A

更新日期：2014-05-01 00:00:00

abstract：:A novel growth phase-associated two-component-type regulator, Fas (fibronectin/fibrinogen binding/haemolytic activity/streptokinase regulator), of Streptococcus pyogenes was identified in the M1 genome sequence, based on homologies to the histidine protein kinase (HPK) and response regulator (RR) part of the Staphyloc...

journal_title：Molecular microbiology

authors： Kreikemeyer B,Boyle MD,Buttaro BA,Heinemann M,Podbielski A

更新日期：2001-01-01 00:00:00

abstract：:Several Fusarium species produce the polyketide mycotoxin zearalenone (ZEA), a causative agent of hyperestrogenic syndrome in animals that is often found in F. graminearum-infected cereals in temperate regions. The ZEA biosynthetic cluster genes PKS4, PKS13, ZEB1 and ZEB2 encode a reducing polyketide synthase, a non-r...

journal_title：Molecular microbiology

authors： Park AR,Son H,Min K,Park J,Goo JH,Rhee S,Chae SK,Lee YW

更新日期：2015-09-01 00:00:00

abstract：:Integrative and conjugative elements (ICEs), a.k.a. conjugative transposons, are mobile genetic elements involved in many biological processes, including pathogenesis, symbiosis and the spread of antibiotic resistance. Unlike conjugative plasmids that are extra-chromosomal and replicate autonomously, ICEs are integrat...

journal_title：Molecular microbiology

authors： Lee CA,Babic A,Grossman AD

更新日期：2010-01-01 00:00:00