Abstract：
PURPOSE:Supplementation with inorganic nitrate has been suggested to be an ergogenic aid for athletes as nitric oxide donor. The purpose of this study was to determine whether ingestion of inorganic sodium nitrate benefits well-trained athletes performing a 40-min exercise test in laboratory conditions. In addition, we investigated the effect of this supplement on plasma levels of endothelin-1 (ET-1) and in nitrated proteins. METHODS:Thirteen trained athletes participated in this randomized, double-blind, crossover study. They performed a 40-min cycle ergometer distance-trial test after two 3-d periods of dietary supplementation with sodium nitrate (10 mg·kg of body mass) or placebo. RESULTS:Concentration of plasma nitrate (256 ± 35 μM) and nitrite (334 ± 86 nM) increased significantly (P < 0.05) after nitrate supplementation compared with placebo (nitrate: 44 ± 11 μM; nitrite: 187 ± 43 nM). In terms of exercise performance, there were no differences in either the mean distance (nitrate: 26.4 ± 1.1 km; placebo: 26.3 ± 1.2 km; P = 0.61) or mean power output (nitrate: 258 ± 28 W; placebo: 257 ± 28 W; P = 0.89) between treatments. Plasma ET-1 increased significantly (P < 0.05) just after exercise in nitrate (4.0 ± 0.8 pg·mL) and placebo (2.4 ± 0.4 pg·mL) conditions. This increase was significantly greater (P < 0.05) in the nitrate group. Levels of nitrated proteins did not differ between treatments (nitrate: preexercise, 91% ± 23%; postexercise, 81% ± 23%; placebo: preexercise, 95% ± 20%; postexercise, 99% ± 19%). CONCLUSION:Sodium nitrate supplementation did not improve a 40-min distance-trial performance in endurance athletes. In addition, concentration of plasma ET-1 increased significantly after exercise after supplementation with sodium nitrate.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Bescós R,Ferrer-Roca V,Galilea PA,Roig A,Drobnic F,Sureda A,Martorell M,Cordova A,Tur JA,Pons Adoi
10.1249/MSS.0b013e3182687e5csubject
Has Abstractpub_date
2012-12-01 00:00:00pages
2400-9issue
12eissn
0195-9131issn
1530-0315journal_volume
44pub_type
杂志文章,随机对照试验abstract：:Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are new and powerful tools to study tissue biochemistry, and to provide precise anatomical visualization of soft tissue structures. This review focuses on the use of these techniques to study exercise-induced muscle injury. MRS measurements sho...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
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abstract：:Regression analysis is often used to demonstrate associations among variables believed to be biologically related. Failure to demonstrate a "significant" relationship may be due to two factors: 1) the variables are truly unrelated, or 2) a relationship exists but goes undetected due to inadequate statistical power. In...
journal_title：Medicine and science in sports and exercise
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doi：
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abstract：PURPOSE:To determine whether a low-cost, commercially available global positioning system (GPS) can be used to study outdoor walking of healthy subjects, allowing the detection of walking and resting (nonwalking) periods and the accurate estimation of speed and distance of each walking periods. METHODS:The same EGNOS-...
journal_title：Medicine and science in sports and exercise
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doi：10.1249/mss.0b013e3180cc20c7
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
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abstract：PURPOSE:The purpose of this study was to investigate neuromuscular characteristics and muscle power as determinants of distance running performance. METHODS:Seventeen male endurance athletes performed a 5-km time trial (5K) that included three separate constant-velocity 200-m laps during the course and a maximal 20-m ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199901000-00020
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198201000-00002
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2004-03-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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pub_type： 杂志文章,随机对照试验
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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