Bronchoconstriction during cross-country skiing: is there really a refractory period?

Abstract:

PURPOSE:The asthmatic airway responds to exercise by bronchodilation (BD) during and bronchoconstriction (BC) after exercise. A refractory period induced by an initial exercise challenge that provides protection against BC during a subsequent exercise bout has also been observed. However, no studies examining during-exercise response or refractoriness during long-duration field exercise by elite athletes have been performed. This study examined airway response and refractoriness during approximately 42-min cross-country ski time trial preceded by a 6- to 9-min 2.5-km high-intensity warm-up ski. METHODS:Eighteen elite athletes cross-country skied seven successive 2.5-km loops. Spirometry was performed pre- and at 5, 10, and 15 min post loop 1; loops 2-7 were treated as a race (XCR) with maneuvers performed within 20 s after loops 2-6 and serially for 15 min after lap 7. RESULTS:Nine of 18 subjects demonstrated a >or=10% fall from baseline in FEV(1) (EIB+): five after lap 1 and four during or after laps 2-7. FEV(1) for EIB+ athletes during XCR was not different from post lap 1 FEV. Only one EIB+ subject demonstrated significant refractoriness. Four EIB+ athletes had a less than 10% fall in FEV after the initial 2.5-km exercise challenge but developed EIB (>or=10% fall) during the subsequent 6 x 2.5 km XCR exercise challenge. FEF(25-75) falls mirrored FEV(1), but demonstrated greater BD during XCR. CONCLUSION:Bronchoconstriction occurs in athletes during prolonged exercise and may thus influence performance. Variability in bronchial hyperresponsiveness onset and the lack of significant refractoriness in our study cohort of athletes is consistent with an exercise bronchoconstrictive dysfunction that is different than frank asthma and is yet to be clearly defined.

journal_name

Med Sci Sports Exerc

authors

Rundell KW,Spiering BA,Judelson DA,Wilson MH

doi

10.1097/00005768-200301000-00004

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

18-26

issue

1

eissn

0195-9131

issn

1530-0315

journal_volume

35

pub_type

杂志文章
  • Modeling maximum oxygen uptake of elite endurance athletes.

    abstract:PURPOSE:To compare the maximum oxygen uptake V0(2max) of elite endurance athletes and to explain why the body mass exponent, necessary to render V0(2max) independent of body mass, appears to be greater than 0.67. METHODS:Study 1: V0(2max) of 174 international sportsmen and women was assessed. Athletes were recruited f...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.MSS.0000053728.12929.5D

    authors: Nevill A,Brown D,Godfrey R,Johnson P,Romer L,Stewart AD,Winter EM

    更新日期:2003-03-01 00:00:00

  • The influence of somatotype on anthropometric prediction of body composition in young women.

    abstract::The influence of somatotype on the validity of anthropometric prediction of body density (Db) in young women (N = 92) was investigated. Three groups of predominantly endomorph (N = 27), mesomorph (N = 35), and ectomorph (N = 30) women were identified by the Heath-Carter and Sheldon somatotyping methods. Discriminant a...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Bulbulian R

    更新日期:1984-08-01 00:00:00

  • Reproducibility of endurance performance on a treadmill using a preloaded time trial.

    abstract:PURPOSE:The purpose of this study was to establish a highly reproducible test to measure endurance performance in runners. METHODS:We evaluated the reproducibility of endurance performance during a 10-km time trial performed on a treadmill after a 90-min preload run at 65% of maximal oxygen uptake VO2max). After scree...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000121954.95892.c8

    authors: Russell RD,Redmann SM,Ravussin E,Hunter GR,Larson-Meyer DE

    更新日期:2004-04-01 00:00:00

  • Interhemispheric plasticity in humans.

    abstract:INTRODUCTION:Chronic unimanual motor practice increases the motor output not only in the trained but also in the nonexercised homologous muscle in the opposite limb. We examined the hypothesis that adaptations in motor cortical excitability of the nontrained primary motor cortex (iM1) and in interhemispheric inhibition...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0b013e31820a94b8

    authors: Hortobágyi T,Richardson SP,Lomarev M,Shamim E,Meunier S,Russman H,Dang N,Hallett M

    更新日期:2011-07-01 00:00:00

  • Facial cooling-induced bradycardia: attenuating effect of central command at exercise onset.

    abstract::Facial cooling (FC) elicits a marked bradycardia at rest that appears to be reduced during exercise. This study was done to delineate the effects of exercise mediated central command from those of muscle afferent feedback and sympathetic stimulation on the attenuation of the bradycardic effect of FC during the onset o...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199703000-00006

    authors: Smith JC,Stephens DP,Winchester PK,Williamson JW

    更新日期:1997-03-01 00:00:00

  • Fitness Is Independently Associated with Central Hemodynamics in Metabolic Syndrome.

    abstract:PURPOSE:Fit individuals with metabolic syndrome (MetS) have lower mortality risk compared with less fit counterparts, despite the presence of obesity as a component of the syndrome. To understand the importance of fitness in treating this condition, we examined the association of fitness and fatness with central hemody...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000916

    authors: Ramos JS,Ramos MV,Dalleck LC,Borrani F,Walker KB,Fassett RG,Sharman JE,Coombes JS

    更新日期:2016-08-01 00:00:00

  • Tape that increases medial longitudinal arch height also reduces leg muscle activity: a preliminary study.

    abstract:PURPOSE:: To evaluate the initial effects of antipronation taping (APT) on foot posture and electromyographic (EMG) activity of tibialis anterior (TA), tibialis posterior (TP), and peroneus longus (PL) muscles during walking. METHODS:: Five asymptomatic individuals who exhibited lower medial longitudinal arch height o...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318162134f

    authors: Franettovich M,Chapman A,Vicenzino B

    更新日期:2008-04-01 00:00:00

  • Antioxidant restriction and oxidative stress in short-duration exhaustive exercise.

    abstract:PURPOSE:To determine the effect of dietary antioxidant restriction on oxidative stress, antioxidant defenses, and exercise performance in athletes. Oxidative stress has been shown to increase during exercise. To alleviate oxidative stress, a high intake of antioxidant rich foods or supplements may be required in traine...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章

    doi:10.1249/01.mss.0000150016.46508.a1

    authors: Watson TA,Callister R,Taylor RD,Sibbritt DW,MacDonald-Wicks LK,Garg ML

    更新日期:2005-01-01 00:00:00

  • Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training.

    abstract:PURPOSE:Lower-limb muscle weakness has often been reported in COPD, and contributes to exercise intolerance. Controversial information is available regarding upper-limb muscle adaptations and the influence of muscle wasting on muscle weakness. We investigated leg and arm muscle function in 59 stable COPD patients (GOLD...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章

    doi:10.1249/01.mss.0000150082.59155.4f

    authors: Franssen FM,Broekhuizen R,Janssen PP,Wouters EF,Schols AM

    更新日期:2005-01-01 00:00:00

  • Cold Water Mediates Greater Reductions in Limb Blood Flow than Whole Body Cryotherapy.

    abstract:PURPOSE:Cold-water immersion (CWI) and whole body cryotherapy (WBC) are widely used recovery methods in an attempt to limit exercise-induced muscle damage, soreness, and functional deficits after strenuous exercise. The aim of this study was to compare the effects of ecologically valid CWI and WBC protocols on postexer...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0000000000001223

    authors: Mawhinney C,Low DA,Jones H,Green DJ,Costello JT,Gregson W

    更新日期:2017-06-01 00:00:00

  • Supervised Resistance Exercise for Patients with Persistent Symptoms of Lyme Disease.

    abstract:PURPOSE:The rapidly increasing incidence of Lyme disease has become a serious public health problem. Persistent symptoms of Lyme disease occur in over 40% of the 300,000 new cases diagnosed annually in the United States and often include debilitating musculoskeletal pain, fatigue, and poor health-related quality of lif...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000683

    authors: D'Adamo CR,McMillin CR,Chen KW,Lucas EK,Berman BM

    更新日期:2015-11-01 00:00:00

  • Effort tolerance in elderly women with different physical activity backgrounds.

    abstract::To study effort tolerance in elderly women with different physical activity backgrounds, 52 physically active (PA) and 42 sedentary control women (CO) aged 66-85 yr were assigned to perform cycle ergometer exercise to their volitional maximum. Oxygen uptake, respiratory exchange ratio (RER), heart rate, work power, an...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199801000-00024

    authors: Kallinen M,Suominen H,Vuolteenaho O,Alen M

    更新日期:1998-01-01 00:00:00

  • Effect of pregnancy on heart rate/oxygen consumption calibration curves.

    abstract:PURPOSE:The purpose of this investigation was to determine heart rate (HR)/oxygen consumption (VO2) calibration curves for exercising and sedentary women during pregnancy and the postpartum periods. METHODS:Fifty-two women were studied at three time points: 20 wk gestation, 32 wk gestation, and 12 wk postpartum. Subje...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200205000-00004

    authors: Pivarnik JM,Stein AD,Rivera JM

    更新日期:2002-05-01 00:00:00

  • Kinematic Mechanisms of How Power Training Improves Healthy Old Adults' Gait Velocity.

    abstract:INTRODUCTION:Slow gait predicts many adverse clinical outcomes in old adults, but the mechanisms of how power training can minimize the age-related loss of gait velocity is unclear. We examined the effects of 10 wk of lower extremity power training and detraining on healthy old adults' lower extremity muscle power and ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001082

    authors: Beijersbergen CM,Granacher U,Gäbler M,Devita P,Hortobágyi T

    更新日期:2017-01-01 00:00:00

  • Microvascular Dilator Function in Athletes: A Systematic Review and Meta-analysis.

    abstract:PURPOSE:Despite the growing research interest in vascular adaptations to exercise training over the last few decades, it remains unclear whether microvascular function in healthy subjects can be further improved by regular training. Herein, we sought to systematically review the literature and determine whether microva...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,meta分析,评审

    doi:10.1249/MSS.0000000000000567

    authors: Montero D,Walther G,Diaz-Cañestro C,Pyke KE,Padilla J

    更新日期:2015-07-01 00:00:00

  • Physiological effects of a weight loss regimen practiced by college wrestlers.

    abstract::The effects of weight loss (dehydration) techniques (which mimicked techniques used prior to actual competition) used by intercollegiate wrestlers on selected physiological parameters (strength, anaerobic power, anaerobic capacity, the lactate threshold (LT), and peak aerobic power) were examined in seven intercollegi...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Webster S,Rutt R,Weltman A

    更新日期:1990-04-01 00:00:00

  • Running Exercise in Obese Pregnancies Prevents IL-6 Trans-signaling in Male Offspring.

    abstract:PURPOSE:Maternal obesity is known to predispose the offspring to impaired glucose metabolism and obesity associated with low-grade inflammation and hypothalamic dysfunction. Because preventive approaches in this context are missing to date, we aimed to identify molecular mechanisms in the offspring that are affected by...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000835

    authors: Bae-Gartz I,Janoschek R,Kloppe CS,Vohlen C,Roels F,Oberthür A,Alejandre Alcazar MA,Lippach G,Muether PS,Dinger K,Ferrari N,Graf C,Dötsch J,Hucklenbruch-Rother E

    更新日期:2016-05-01 00:00:00

  • Activity classification using the GENEA: optimum sampling frequency and number of axes.

    abstract:INTRODUCTION:The GENEA shows high accuracy for classification of sedentary, household, walking, and running activities when sampling at 80 Hz on three axes. It is not known whether it is possible to decrease this sampling frequency and/or the number of axes without detriment to classification accuracy. The purpose of t...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e31825e19fd

    authors: Zhang S,Murray P,Zillmer R,Eston RG,Catt M,Rowlands AV

    更新日期:2012-11-01 00:00:00

  • Effects of hypoxic interval training on cycling performance.

    abstract:PURPOSE:The aim of this study was to test the hypothesis that intermittent hypoxic interval training improves sea level cycling performance more than equivalent training in hypoxia or normoxia. METHODS:Thirty-three well-trained cyclists and triathletes (25.9 +/- 2.7 yr, VO(2max) 66.1 +/- 6.1 mL.min(-1).kg(-1)) were di...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章

    doi:10.1249/01.mss.0000150077.30672.88

    authors: Roels B,Millet GP,Marcoux CJ,Coste O,Bentley DJ,Candau RB

    更新日期:2005-01-01 00:00:00

  • Physical activity and the initiation of high-risk health behaviors in adolescents.

    abstract::The association of physical activity to the initiation of health risk behaviors was examined in a 3-yr prospective study of a population-based cohort of 1245 adolescents aged 12-16 yr. Four hundred thirty-seven students (35% of the cohort) were identified at baseline via self-report survey as never having smoked cigar...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Aaron DJ,Dearwater SR,Anderson R,Olsen T,Kriska AM,Laporte RE

    更新日期:1995-12-01 00:00:00

  • Elite Distance Runners: A 45-Year Follow-up.

    abstract:PURPOSE:The present longitudinal study assessed cardiorespiratory capacity and running economy of Olympic athletes over several decades to measure changes in fitness in an elite group during aging. METHODS:Twenty-six male runners training for the 1968 Olympics were recruited. HR, V˙O2max, ventilation, and running econ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001407

    authors: Everman S,Farris JW,Bay RC,Daniels JT

    更新日期:2018-01-01 00:00:00

  • Use of protective equipment in a cohort of rugby players.

    abstract:PURPOSE:To describe the level of usage of protective devices and equipment in a cohort of New Zealand rugby players. METHODS:Male and female players (N = 327) from a range of competitive grades were followed over the course of the season. Participants were interviewed weekly about their participation in rugby and use ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200112000-00024

    authors: Marshall SW,Waller AE,Loomis DP,Feehan M,Chalmers DJ,Bird YN,Quarrie KL

    更新日期:2001-12-01 00:00:00

  • Genetic correlation of exercise with heart rate and respiratory sinus arrhythmia.

    abstract:PURPOSE:A twin design was used to test whether the association between exercise behavior and heart rate and the association between exercise behavior and respiratory sinus arrhythmia (RSA) derive from a common genetic factor. METHODS:Data were available from 157 adolescent (aged 13-22) and 208 middle-aged twin pairs (...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.MSS.0000079073.20399.11

    authors: De Geus EJ,Boomsma DI,Snieder H

    更新日期:2003-08-01 00:00:00

  • Healthy lifestyles of former Finnish world class athletes.

    abstract::Recently, Sarna et al. (Med. Sci. Sports Exerc. 25:237-244, 1993) reported increased mean life expectancy in former world class athletes. Because lifestyle is associated with longevity, we have examined whether health habits of former Finnish male athletes (N = 1274; present mean age: 57.5, range: 36-94 yr) differed f...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-199402000-00013

    authors: Fogelholm M,Kaprio J,Sarna S

    更新日期:1994-02-01 00:00:00

  • Response of the myocardium to exercise: sex-specific regulation of hsp70.

    abstract::Sex is a potent modifier of the cardiovascular system because males and females differ in several aspects of the heart's biology and physiology. Epidemiologically, premenopausal women possess a distinct advantage over men in the occurrence of cardiovascular heart disease; however, this advantage shifts to men once a n...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1249/MSS.0b013e3181621311

    authors: Milne KJ,Noble EG

    更新日期:2008-04-01 00:00:00

  • J.B. Wolffe memorial lecture. Activity-induced fast to slow transitions in mammalian muscle.

    abstract::Chronically increased contractile activity by low-frequency stimulation induces a transformation of fast- into slow-twitch muscle fibers in the rabbit. This transformation is progressive with the duration of the stimulation and affects various functional systems of the muscle fiber in an orderly sequence. Early change...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:

    authors: Pette D

    更新日期:1984-12-01 00:00:00

  • Cold exposure: human immune responses and intracellular cytokine expression.

    abstract::It is commonly believed that exposure to cold environmental temperatures depresses immune function and increases the risk for infection. This review paper will 1) present an overview of human physiological responses to cold exposure, 2) present the human studies examining the effects of cold exposure on immune respons...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1097/00005768-200212000-00023

    authors: Castellani JW,M Brenner IK,Rhind SG

    更新日期:2002-12-01 00:00:00

  • Resistance training during unweighting maintains muscle size and function in human calf.

    abstract:PURPOSE:A 20-d 6 degrees head-down tilt bed rest project was conducted to evaluate the effect of dynamic leg press and plantar flexion resistance training on muscle size and function in human plantar flexors (PF) throughout the prolonged bed rest. METHODS:Twelve healthy men participated in this study and were divided ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1249/01.MSS.0000058367.66796.35

    authors: Akima H,Ushiyama J,Kubo J,Tonosaki S,Itoh M,Kawakami Y,Fukuoka H,Kanehisa H,Fukunaga T

    更新日期:2003-04-01 00:00:00

  • Plasma catecholamine response to acute psychological stress in humans: relation to aerobic fitness and exercise training.

    abstract::Existing cross-sectional studies on plasma catecholamine activity provide no support for the concept that a markedly high level of aerobic fitness modifies sympathoadrenal response to an acute psychological challenge in humans. In contrast, compromised sympathetic nervous system activity has been observed in individua...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:

    authors: Sothmann MS,Hart BA,Horn TS

    更新日期:1991-07-01 00:00:00

  • Ultrasound-guided percutaneous longitudinal tenotomy for the management of patellar tendinopathy.

    abstract::Thirty-eight athletes with unilateral patellar tendinopathy (17 with a tendinopathy of the main body of the tendon, and 21 with an insertional tendinopathy) underwent ultrasound-guided multiple percutaneous longitudinal tenotomy under local anaesthetic infiltration after failure of conservative management. Thirty-four...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199911000-00003

    authors: Testa V,Capasso G,Maffulli N,Bifulco G

    更新日期:1999-11-01 00:00:00