Abstract：
INTRODUCTION:Chronic unimanual motor practice increases the motor output not only in the trained but also in the nonexercised homologous muscle in the opposite limb. We examined the hypothesis that adaptations in motor cortical excitability of the nontrained primary motor cortex (iM1) and in interhemispheric inhibition from the trained to the nontrained M1 mediate this interlimb cross education. METHODS:Healthy, young volunteers (n=12) performed 1000 submaximal voluntary contractions (MVC) of the right first dorsal interosseus (FDI) at 80% MVC during 20 sessions. RESULTS:Trained FDI's MVC increased 49.9%, and the untrained FDI's MVC increased 28.1%. Although corticospinal excitability in iM1, measured with transcranial magnetic stimulation (TMS) before and after every fifth session, increased 6% at rest, these changes, as those in intracortical inhibition and facilitation, did not correlate with cross education. When weak and strong TMS of iM1 were delivered on a background of a weak and strong muscle contraction, respectively, of the right FDI, excitability of iM1 increased dramatically after 20 sessions. Interhemispheric inhibition decreased 8.9% acutely within sessions and 30.9% chronically during 20 sessions and these chronic reductions progressively became more strongly associated with cross education. There were no changes in force or TMS measures in the trained group's left abductor minimi digiti and there were no changes in the nonexercising control group (n=8). CONCLUSIONS:The findings provide the first evidence for plasticity of interhemispheric connections to mediate cross education produced by a simple motor task.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Hortobágyi T,Richardson SP,Lomarev M,Shamim E,Meunier S,Russman H,Dang N,Hallett Mdoi
10.1249/MSS.0b013e31820a94b8subject
Has Abstractpub_date
2011-07-01 00:00:00pages
1188-99issue
7eissn
0195-9131issn
1530-0315journal_volume
43pub_type
杂志文章,随机对照试验abstract：PURPOSE:Cardiac aldosterone might be involved in the deleterious effects of nandrolone decanoate (ND) on the heart. Therefore, we investigated the involvement of cardiac aldosterone, by the pharmacological block of AT1 or mineralocorticoid receptors, on cardiac hypertrophy and fibrosis. METHODS:Male Wistar rats were r...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318217e8b6
更新日期：2011-10-01 00:00:00
abstract：:Energy expenditure during bicycling on flat terrain depends predominantly on air resistance, which is a function of total frontal area (bicycle and rider), coefficient of drag, and air speed. Body position on the bicycle may affect energy expenditure by altering either frontal area or coefficient of drag. In this stud...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：INTRODUCTION:Regular exercise can reduce the risk of developing cardiovascular disease through risk factor modification, with high-intensity exercise and more recently small muscle mass training providing alternatives to moderate-intensity exercise. METHODS:This study randomly assigned 53 healthy middle-age adults (ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1249/MSS.0000000000002053
更新日期：2019-11-01 00:00:00
abstract：INTRODUCTION:Insulin resistance in obesity is decreased after successful diet and exercise. Aerobic exercise training alone was evaluated as an intervention in subjects with the metabolic syndrome. METHODS:Eighteen nondiabetic, sedentary subjects, 11 with the metabolic syndrome, participated in 8 wk of increasing inte...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31829a6ce8
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abstract：PURPOSE:The development of valid measures of built environments relevant for physical activity is an important step toward controlling the global epidemic of physical inactivity-related noncommunicable diseases and deaths. This study assessed the construct validity of a self-report neighborhood environment walkability ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001131
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199604000-00019
更新日期：1996-04-01 00:00:00
abstract：UNLABELLED:Clinical treatment in physical rehabilitation routinely uses perceived relative forces. PURPOSE:This study used psychophysical methods to quantify subjects' errors during submaximal muscular force production. METHODS:A sample of young adult (aged 23 +/- 3 yr) females (N = 60, 62 +/- 14 kg) and males (N = 5...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200002000-00028
更新日期：2000-02-01 00:00:00
abstract：:Fatigue can be defined as the failure to maintain an expected power output. This is often an antecedent to some sports-related injury. It is important for those involved in physical performance to be familiar with the variety of mechanisms which can lead to fatigue. All too often, a single factor is described as the c...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1990-08-01 00:00:00
abstract：PURPOSE:To compare four different methods of measuring physical activity (PA) in adult women under free-living conditions. METHODS:Twelve women participated in a 7-d period during which PA was assessed via self-report, accelerometry and step-counting. Subjects wore at the waist a Tritrac-R3D accelerometer, a Computer ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200007000-00021
更新日期：2000-07-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:This study investigated the contributions of physical fitness and body composition to 24-h fat oxidation in adults under sedentary conditions in a whole-room calorimeter. METHODS:The following measurements were studied in 109 adults (49 male/45 female) at least 36 h after a bout of exercise: 1) aerobic fitne...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200004000-00013
更新日期：2000-04-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200012000-00013
更新日期：2000-12-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：PURPOSE:This study was conducted to determine if fifth-grade students who walked or bicycled to school on a regular basis were more physically active than those that did not. METHODS:The sample consists of 219 fifth-grade students (10.3 +/- 0.6 yr, 44% male, 58% minority) from eight randomly selected urban and suburba...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000179102.17183.6b
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:Previous studies have suggested that higher levels of physical activity may lower lung cancer risk; however, few prospective studies have evaluated lung cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of recent physical activity habits. METHODS:Thirty-eight thousand men, ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181c47b65
更新日期：2010-05-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199705000-00008
更新日期：1997-05-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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更新日期：2008-08-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199610000-00039
更新日期：1996-10-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2004-04-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
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更新日期：2006-09-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1988-12-01 00:00:00
abstract：PURPOSE:Previous research identified decreased overall and cardiovascular mortality for National Football League (NFL) players from the 1959-1988 era. The present study explored the mortality risk among recent NFL players who played in an era of heavier linemen and nearly year-round physical conditioning. METHODS:This...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-07-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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更新日期：2009-01-01 00:00:00
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION:The application of an autologous plasma rich in growth factors is beneficial in restoring connective tissues, as shown by clinical evidence in oral surgery and more recently in arthroscopic anterior cruciate ligament reconstruction and two cases of ruptured Achilles tendon in professional athletes. This is...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000089344.44434.50
更新日期：2003-10-01 00:00:00
abstract：PURPOSE:To determine whether physical performance adaptation is impaired in smokers during early stages of military training and to examine some of the putative mechanistic candidates that could explain any impairment. METHODS:We examined measures of oxidative stress (malondialdehyde [MDA], lipid hydroperoxides), infl...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002224
更新日期：2020-05-01 00:00:00
