Abstract：
INTRODUCTION:Regular exercise can reduce the risk of developing cardiovascular disease through risk factor modification, with high-intensity exercise and more recently small muscle mass training providing alternatives to moderate-intensity exercise. METHODS:This study randomly assigned 53 healthy middle-age adults (age, 62 ± 6 yr) to complete 24 sessions (8 wk; 3 d·wk) of exercise training, using either high-intensity double-leg cycling (n = 17; HITDL), high-intensity single-leg cycling (n = 18; HITSL), or moderate-intensity double-leg cycling (n = 18; MCTDL). Biomarkers of cardiovascular risk (total cholesterol, triglycerides, HDL-c, LDL-c, apo-B48, and glucose), anthropometry measures (body mass, body mass index, waist circumference, and waist-to-hip ratio), resting blood pressure, and aerobic capacity were assessed pre- and postintervention. RESULTS:Total work completed was greater (P < 0.01) in MCTDL (5938 ± 1462 kJ) compared with the HITDL (3462 ± 1063 kJ) and HITSL (4423 ± 1875 kJ). Pre- to posttraining differences were observed for waist-to-hip ratio (0.84 ± 0.09 vs 0.83 ± 0.09; P < 0.01), resting systolic blood pressure (129 ± 11 vs 124 ± 12 mm Hg; P < 0.01), total cholesterol (5.87 ± 1.17 vs 5.55 ± 0.98 mmol·L; P < 0.01), and LDL-c (3.70 ± 1.04 vs 3.44 ± 0.84 mmol·L; P < 0.01), with no differences between conditions. In addition, aerobic capacity increased after training (22.3 ± 6.4 vs 24.9 ± 7.6 mL·kg·min; P < 0.01), with no differences between conditions. CONCLUSION:These findings suggest that all three modes of exercise can be prescribed to achieve cardiovascular risk reduction in an aging population.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Gordon N,Abbiss CR,Maiorana AJ,James AP,Clark K,Marston KJ,Peiffer JJdoi
10.1249/MSS.0000000000002053subject
Has Abstractpub_date
2019-11-01 00:00:00pages
2234-2242issue
11eissn
0195-9131issn
1530-0315journal_volume
51pub_type
杂志文章,多中心研究,随机对照试验abstract：PURPOSE:This study aimed to examine the effects of footwear and neuromuscular fatigue induced by short distance trail running (TR) on running economy (RE) and biomechanics in well-trained and traditionally shod runners. METHODS:RE, vertical and leg stiffness (Kvert and Kleg), as well as foot strike angle were measured...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000981
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:Orienteering athletes must adapt to running on various surfaces, with biomechanics likely contributing to performance. Here, our aims were to identify the effect of athletic status and of surface on the running biomechanics of orienteers. METHODS:Seven elite and seven amateur male orienteers ran 20 m on road, ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000413
更新日期：2015-02-01 00:00:00
abstract：PURPOSE:The importance of the brain in sports was recently confirmed by the negative effect of mental fatigue (MF) on sport-specific psychomotor skills. Creatine supplementation improves strength but can also improve cognitive functioning. To explore the role of creatine in combating MF, we evaluated whether creatine s...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000002122
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:Loud sounds can decrease reaction time (RT) and increase force generated during voluntary contractions. Accordingly, we hypothesized that the loud starter's pistol at the Olympic Games allows runners closer to the starter to react sooner and stronger than runners farther away. METHODS:RT for the 100/110 m...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31816770e1
更新日期：2008-06-01 00:00:00
abstract：:A group of 103 female weight lifters (WL) and 92 control (C) women answered a survey concerning eating behavior and attitudes (including the Eating Disorder Inventory) and menstrual function. The incidence of menstrual dysfunction, defined as oligomenorrhea plus amenorrhea, was significantly higher for the WL (30%) th...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：PURPOSE:We aimed to evaluate in a longitudinal study the effect of intensive training on cardiac autonomic control in athletes using 24-h heart rate variability analysis. METHODS:Time and frequency domain measures of heart rate variability were calculated from 24-h Holter monitoring in 15 high level bicyclists (mean a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199805000-00008
更新日期：1998-05-01 00:00:00
abstract：INTRODUCTION:Oral beta2-agonist administration improves muscle function in persons without asthma. We performed a double-blind, randomized, controlled crossover study to assess whether acute inhaled salbutamol administration improves muscle strength and fatigability in healthy moderately trained subjects. METHODS:Quad...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31816b87aa
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:Neural adaptations to strength training have long been recognized, but knowledge of mechanisms remains incomplete. Using novel techniques and a design which limited experimental bias, this study examined if 4 wk of strength training alters voluntary activation and corticospinal transmission. METHODS:Twenty-one...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001367
更新日期：2017-11-01 00:00:00
abstract：INTRODUCTION:Androgen deprivation therapy (ADT) is associated with significant bone loss and an increase in fracture risk among prostate cancer survivors (PCS). We investigated whether impact + resistance training could stop ADT-related declines in bone mineral density (BMD) among PCS on ADT. METHODS:We randomized 51 ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000265
更新日期：2014-08-01 00:00:00
abstract：:The purpose of the present investigation was to examine the wet suit effect on 8 swimmers and 8 triathletes. For swimmers, the performances of a 400-m swim with and without wet suit were not statistically different (4 min 12.5 +/- 8 s vs 4 min 13.9 +/- 4 s) while for triathletes the swim times were reduced by 19 s (4 ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：INTRODUCTION:Alternative high school (AHS) students are an underserved population of youth at greater risk for poor health behaviors and outcomes. Little is known about their physical activity patterns. PURPOSE:: The purpose of this study was to describe 1) physical activity levels of students attending alternative hi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318182092b
更新日期：2008-12-01 00:00:00
abstract：:The purpose of this study was to determine the validity and evaluate the accuracy of a portable telemetric oxygen uptake analyzer (K2). Two experiments were carried out: a) using a mechanical lung, the accuracy of the K2 to measure oxygen fractions and minute ventilation following 10 and 60 min of warm-up was determin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:This study, theoretically based on the Exercise Self-Esteem Model, EXSEM, examined effects of exercise modality on physical and global self-esteem (PSE, GSE) in breast cancer survivors. The EXSEM posits GSE at the apex with PSE feeding into GSE. PSE has three subdomains: physical condition (PC), attractive body...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31822cb5f2
更新日期：2012-02-01 00:00:00
abstract：:We present a computer simulation of a two-compartment model of the systemic circulation which demonstrates how this model can be used to understand the mechanism(s) for the maximal exercise cardiac output (Q). The model consists of two parallel vascular channels, the splanchnic channel (all blood draining through the ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:Although many studies have attempted to examine the effect of hypohydration on strength, power, and high-intensity endurance, few have successfully isolated changes in total body water from other variables that alter performance (e.g., increased core temperature), and none have documented the influence of hypoh...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/mss.0b013e3180de5f22
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To examine whether normalized quadriceps and hamstring strength would predict quadriceps and hamstring muscle activation amplitudes and whether these neuromuscular factors would predict knee kinematics and kinetics during a drop jump task. METHODS:Thirty-nine females and 39 males were measured for isometric qu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e3b3f
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare architectural characteristics of leg muscles of sprinters and distance runners. METHODS:Skeletal muscle architectural characteristics were studied in 23 elite male 100-m sprinters (SPR, 10.0-10.9 s for 100 m), 24 elite male distance runners (DR, 13.5-14.5 min for 5000 m...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200006000-00014
更新日期：2000-06-01 00:00:00
abstract：PURPOSE:To date, no study has examined the synergistic effects of a nutrition and combination of aerobic and strength training (CAST) on both adiposity and metabolic parameters in overweight Latina adolescent females. The goal was to assess if a 16-wk nutrition plus CAST pilot study had stronger effects on reducing adi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31819b6aea
更新日期：2009-07-01 00:00:00
abstract：:The purpose of this study was to compare gastric emptying (GE) responses during intense, prolonged cycling and running. It is important to discern whether gastric emptying (GE) responses are exercise-mode specific, since the findings of cycling and running studies are often compared and applied to one another. Ten mal...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：PURPOSE:Prolonged sitting time (ST) is associated with higher mortality. However, previous studies used only a single measure of ST at baseline, so they could not directly assess the effect of continued exposure to high ST, or of changes in ST, on mortality. We prospectively assessed the association of continued sedent...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182897e87
更新日期：2013-08-01 00:00:00
abstract：:Sprint-trained athletes demonstrate a remarkable ability to perform exercise which results in fatigue quickly. However, the mechanisms for these enhanced performance capabilities have not been fully elucidated. Elevation in glycolytic enzymes and increased fast-twitch fiber compositions which would result in an enhanc...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1984-08-01 00:00:00
abstract：PURPOSE:Despite endorsement by various health organizations, there is a lack of research on the effectiveness of perceptually regulated exercise training (PRET) as a method of exercise intensity prescription. The purpose of this study was to confirm the efficacy of an 8-wk PRET program clamped at RPE13 to improve aerob...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31824d266e
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Recent work has identified deficits in dual-task gait balance control for up to 2 months after adolescent concussion; however, how resumption of preinjury physical activities affects recovery is unknown. PURPOSE:The objective of this study is to examine how return to activity (RTA) affects recovery from con...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000462
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:Caffeine is an exercise performance enhancer widely used by individuals engaged in training or competition under heat-stressed conditions. Caffeine ingestion during exercise in the heat is believed to be safe, since it does not greatly affect body temperature responses, heart rate or body fluid status. How...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002537
更新日期：2020-10-07 00:00:00
abstract：PURPOSE:Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics is frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001201
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:Highly trained endurance athletes train and race at relatively high intensities and are often confronted with challenges throughout a running event. The purpose of this study was to examine the effects of the anticipation of a proposed challenge on effort sense, heart rate (HR), ventilation ([dotVE), and ventil...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199910000-00016
更新日期：1999-10-01 00:00:00
abstract：:Studies using wearable sensors to measure posture, physical activity (PA), and sedentary behavior typically use a single sensor worn on the ankle, thigh, wrist, or hip. Although the use of single sensors may be convenient, using multiple sensors is becoming more practical as sensors miniaturize. PURPOSE:We evaluated ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002306
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:High school cross-country runners have a high incidence of injury, particularly at the shin and knee. An increased step rate during running has been shown to reduce impact forces and loading of the lower extremity joints. The purpose of this prospective study was to examine step rate as a risk factor for injury...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000890
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:Physical exercise or hypoxic exposure influences hemorheology and acid-base homeostasis. Band 3 protein in erythrocytes modulates cells' rheological properties and anion transport ability. This study investigated how cycling aerobic interval training (AIT) and moderate continuous training (MCT) affect the rheol...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000730
更新日期：2016-01-01 00:00:00
abstract：:Many experimental studies have utilized the activity of dopamine-beta-hydroxylase (DBH) as an index of sympathetic activity, since this enzyme is not submitted to uptake mechanisms or to enzymatic metabolism as are the circulating catecholamines norepinephrine (NE) and epinephrine (E). However, large discrepancies hav...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198512000-00011
更新日期：1985-12-01 00:00:00
