Abstract：
PURPOSE:This study aimed to determine the effect of acute exercise on the proliferation and expression of activation markers on T-lymphocytes. METHODS:Seventeen well-trained male endurance runners completed 60 min of treadmill running at 95% of ventilatory threshold and a resting, no exercise, control session at the same time of day. Five blood samples were collected at each session: before exercise, mid-exercise, immediately after exercise, and 30 min and 60 min after exercise. Isolated peripheral blood mononuclear cells (PBMC) were stimulated with the mitogen PHA. Activation was measured using the expression of CD69 (assessed by three-color flow-cytometry), and cellular proliferation was assessed using 3-(4,5-dimethlthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye uptake. RESULTS:At all sampling points, there was a significant difference (P < 0.05) in the percentage of CD4 and CD8 cells that became activated (CD69+) after mitogen stimulation (68% of CD4 compared with 45% of CD8 cells). Exercise had no effect on the percentage of cells that became activated in response to mitogen. There was a significant exercise-induced decrease in lymphocyte proliferation of PBMC, but when expressed per-T-cell (CD3+), there was no difference between the exercise and control condition. CONCLUSION:This study indicated that on an individual cell basis 1 h of exercise at 95% of ventilatory threshold did not alter the ability of T-lymphocytes (CD3+) or T-lymphocyte subsets (CD3+CD4+ and CD3+CD8+) to become activated and did not alter the ability of T-lymphocytes to proliferate.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Green KJ,Rowbottom DG,Mackinnon LTdoi
10.1249/01.MSS.0000058361.82096.26subject
Has Abstractpub_date
2003-04-01 00:00:00pages
582-8issue
4eissn
0195-9131issn
1530-0315journal_volume
35pub_type
杂志文章abstract：PURPOSE:High school cross-country runners have a high incidence of injury, particularly at the shin and knee. An increased step rate during running has been shown to reduce impact forces and loading of the lower extremity joints. The purpose of this prospective study was to examine step rate as a risk factor for injury...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000890
更新日期：2016-07-01 00:00:00
abstract：:In "normal" conditions (e.g., normoxia, absence of pathological conditions) convective and diffusive O(2) delivery to skeletal muscle fibers do not seem to represent important determinants for the kinetics of adjustment of oxidative phosphorylation following increases in metabolic demand. Whereas a limiting role by PD...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/01.mss.0000177472.67419.0a
更新日期：2005-09-01 00:00:00
abstract：:This paper introduces the terminology and application of parameter estimation techniques for clarifying models of pulmonary gas-exchange control dynamics. Results are given of modeled first-order systems, and the extension of such models to higher orders is discussed with examples. It is emphasized that justification ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：PURPOSE:The purposes of this study were to assess a) the effectiveness of Masai Barefoot Technology (MBT) shoe in reducing knee pain in persons with knee osteoarthritis (OA) and (b) changes in balance, ankle and knee ROM, and ankle strength compared with a high-end walking shoe for 12 wk. METHODS:The research design w...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/01.mss.0000228364.93703.53
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:The aim was to determine the feasibility of a 6-wk speed-based exercise program that could be used to initiate new exercise behaviors and to improve rapid movement in older adults approaching frailty. METHODS:The intervention group included 14 older adults (3 males and 11 females; mean ± SD, age = 70 ± 7.6 yr,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001069
更新日期：2017-01-01 00:00:00
abstract：:This report demonstrates the effect of voluntary exercise in attenuating increases in heart rate (HR) caused by chronic stress in an animal model of stress-induced hypertension, the borderline hypertensive rat (BHR). Exercise training also protected against the hypertensive effects of stress in 16-wk-old, but not 10-w...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：PURPOSE:To evaluate the impact of applying seven calibration equations (CE) in the estimation of free-living total energy expenditure (TEE) over 2-3 d in seven boys (mean +/- SD age 9.4+/-0.4 yr) by the Flex heart rate (HR) method. METHODS:HR and oxygen consumption were measured simultaneously for eight activities (ly...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200008000-00022
更新日期：2000-08-01 00:00:00
abstract：PURPOSE:This study aimed to quantify the frequency, magnitude, and location of head impacts sustained by male and female collegiate ice hockey players during two seasons of play. METHODS:During two seasons, 88 collegiate athletes (51 females, 37 males) on two female and male National Collegiate Athletic Association va...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31822b0ab4
更新日期：2012-02-01 00:00:00
abstract：:A decrease in hepatic lactate dehydrogenase (LDH) activity following endurance training has been a consistent observation. In the present study, we sought to determine whether the training-induced decrease in hepatic LDH activity (pyruvate = substrate) was associated with a shift in the isoenzyme profile and/or altera...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：PURPOSE:Elevated rates of cardiometabolic diseases have been observed in former American football players. The current study sought to determine whether change in body mass index (ΔBMI) after retirement influences the prevalence of CHD, diabetes, or high blood pressure (HBP) in former professional football players. ME...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001492
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics is frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001201
更新日期：2017-06-01 00:00:00
abstract：:The effects of steady state exercise on the power spectrum of heart rate variability were studied in 19 healthy subjects. Continuous ECG signals were recorded during 1) 15 min of rest in the supine state, 2) 10 min of standing, 3) 10 min of steady state exercise at 50% of maximum predicted power output on a cycle ergo...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：PURPOSE:To compare the cardiovascular reactivity response to mental challenge of aerobically trained and untrained preadolescent boys. METHODS:Heart rate (HR) and blood pressure, as well as stroke volume, total peripheral resistance, rate pressure product, and cardiac contractility response in 15 aerobically trained (...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1249/01.MSS.0000078935.78895.8E
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:The study's purpose was to relate body mass index (BMI) to body fat percentage as measured by dual-energy x-ray absorptiometry in female elite athletes from different sports and nonathletic controls and to investigate what characterizes the athletes with unhealthy low and high body fat values. METHODS:This stu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31823fe4ef
更新日期：2012-05-01 00:00:00
abstract：:The ventilatory stimulating effects of hypoxia occurring at carotid bodies are potentiated by exercise. However, hypoxia also has central ventilatory depressive effects; the potential interactions between this hypoxic depression and exercise have not been studied. We examined the ventilatory response to a 20 min perio...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:To inform the development of bone-specific physical activity (PA) assessment methods and contribute to bone-specific PA guidelines, accelerometer outcomes that provide the most valid estimates of skeletal loading in adults must be identified. PURPOSE:The aims of this project were two-fold. First, to assess the concur...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002562
更新日期：2020-11-07 00:00:00
abstract：:To test whether strenuous exercise with and without caloric restriction alters LH secretion, and whether these changes are apparent in the immediate post-exercise period, LH pulse parameters were studied in four moderately trained eumenorrheic women over three successive menstrual cycles. Blood samples were obtained 5...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-10-01 00:00:00
abstract：PURPOSE:High-throughput profiling of metabolic status (metabolomics) allows for the assessment of small-molecule metabolites that may participate in exercise-induced biochemical pathways and corresponding cardiometabolic risk modification. We sought to describe the changes in a diverse set of plasma metabolite profiles...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001594
更新日期：2018-07-01 00:00:00
abstract：PURPOSE:This study aimed to determine whether competitive intermittent exercise in the heat affects recovery, aggravates markers of muscle fiber damage, and delays the recovery of performance and muscle glycogen stores. METHODS:Plasma creatine kinase, serum myoglobin, muscle glycogen, and performance parameters (sprin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31827ded04
更新日期：2013-05-01 00:00:00
abstract：:The purpose of this study was to determine the validity and evaluate the accuracy of a portable telemetric oxygen uptake analyzer (K2). Two experiments were carried out: a) using a mechanical lung, the accuracy of the K2 to measure oxygen fractions and minute ventilation following 10 and 60 min of warm-up was determin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:Above a given exercise intensity, rapid muscle fatigue will occur. We explored the possibility of assessing torque threshold for peripheral fatigue during single-legged repetitive isometric knee extensor exercise. We hypothesized this fatigue threshold to be related to the general aerobic fitness level and the ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318249d701
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:The midfoot is instrumental to foot function; however, quantifying its roles in human movement has been difficult. A forceful dynamic activity like landing may help elucidate the midfoot's contribution to foot energetics and function. The main purpose of this study was to measure midtarsal joint kinematics and ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001765
更新日期：2019-01-01 00:00:00
abstract：:Although no conclusive evidence exists to suggest that vitamin supplementation improves athletic performance in nutritionally adequate individuals, exercise may increase requirements for certain vitamins in individuals with marginal vitamin stores. This review summarizes results from recent research studies of vitamin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:The purpose of this study was to extend our knowledge of running related injuries by determining whether relationships exist between selected anthropometric, biomechanical, muscular strength and endurance, and training variables and runners afflicted with patellofemoral pain (PFP). Specifically, the objectives of this...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:The purpose of this experiment was to determine whether reflexive, or more broadly, automatic hamstrings excitation could be elicited during isometric, maximum effort, step increases in knee extension torque. Eight healthy subjects without lower extremity dysfunction or injury performed maximum effort isometric knee e...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：PURPOSES:To validate the energy expenditure estimated from The Minnesota Leisure Time Physical Activity Questionnaire (MLTPAQ) with total energy expenditure (TEE) measured by doubly labeled water (DLW), and to present and examine the validity of an extended version of the MLTPAQ with additional questions about inactivi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000093608.95629.85
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate neuromuscular characteristics and muscle power as determinants of distance running performance. METHODS:Seventeen male endurance athletes performed a 5-km time trial (5K) that included three separate constant-velocity 200-m laps during the course and a maximal 20-m ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199901000-00020
更新日期：1999-01-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to validate a parent proxy record of children's physical activity with CSA Model 7164 accelerometers. METHODS:A parent proxy record was developed to record children's activity after school on weekdays and all day long on weekends for 7 d. Parents recorded both duration and in...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000174906.38722.2e
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:Physical activity plays an important role in the prevention of many serious diseases. To develop targeted strategies that encourage physical activity, knowledge of stability of physical activity levels over time is essential. The aim of this study was to examine tracking of leisure time physical activity in adu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182084562
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:This study examined the validity of the assumption of lower-extremity kinematic parameter reproducibility and symmetry during running with different velocities and stride frequencies. METHODS:Each of 12 female long-distance runners ran on a treadmill in combinations of three different velocities (2.5, 3.0, and...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000069337.49567.F0
更新日期：2003-06-01 00:00:00
