Abstract：
:Strain improvement by genetic manipulation or optimization of fermentation conditions for overproduction of vitamin B(12) has a drawback due to feed back inhibition. To resist the feed back inhibition by analogues of vitamin B(12) in Propionibacterium freudenrechii subsps. shermanii (OLP-5), we have tested with microbially separated B(12) analogues from three different strains. Microbial analogues were differentiated from commercially available vitamin B(12) by high pressure liquid chromatography and spectrophotometric method. An analogue isolated from NRRL-B-4327 was shown to increase vitamin B(12) concentration from 18.53 ± 0.15 to 31.67 ± 0.58 mg/l in OLP-5 strain. The presence of chemical analogue (ICH(2) Co(DH)(2) (H(2)Py)(4)) increased vitamin B(12) production from 16.13 ± 0.15 to 18.53 ± 0.15 mg/l in OLP-5. These findings revealed that addition of B(12) analogues in fermentation media have developed strain resistance to feed back inhibition by vitamin B(12).
journal_name
World J Microbiol Biotechnoljournal_title
World journal of microbiology & biotechnologyauthors
Thirupathaiah Y,Swarupa Rani C,Sudhakara Reddy M,Venkateswar Rao Ldoi
10.1007/s11274-012-1011-8subject
Has Abstractpub_date
2012-05-01 00:00:00pages
2267-71issue
5eissn
0959-3993issn
1573-0972journal_volume
28pub_type
杂志文章abstract：:Endophytes are recognised as potential sources of novel secondary metabolites, including enzymes and drugs, with applications in medicine, agriculture and industry. There is a growing need for new enzymes, including proteases, for use in industry that can function under a variety of conditions. In this study, three fu...
journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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更新日期：2017-08-01 00:00:00
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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更新日期：2012-03-01 00:00:00
abstract：:The capacity of different naphthoquinones to inhibit and eradicate Yersinia enterocolitica biofilm was investigated and possible mechanisms of action were evaluated. Inhibition of biofilm formation and cell viability, quorum sensing (QS) inhibition and oxidative stress generation of 23 naphthoquinones were assayed aga...
journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
doi：10.1007/s11274-020-02971-7
更新日期：2021-01-18 00:00:00
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journal_title：World journal of microbiology & biotechnology
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doi：10.1007/BF01201871
更新日期：1992-05-01 00:00:00
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journal_title：World journal of microbiology & biotechnology
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更新日期：2020-07-06 00:00:00
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
doi：10.1007/s11274-017-2399-y
更新日期：2018-02-15 00:00:00
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
abstract：:The extensive exploitation and usage of lead compounds result in severe lead(II) pollution in water and soil environments, even in agricultural land, threatening the health of animals and humans via food chains. The recovery and remediation of lead(II) from water and soil environments have been intensively concerned i...
journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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abstract：:The biomass degrading enzymatic potential of 101 thermophilic bacterial strains isolated from a volcanic environment (Santorini, Aegean Sea, Greece) was assessed. 80 % of the strains showed xylanolytic activity in Congo Red plates, while only eight could simultaneously hydrolyze cellulose. Fifteen isolates were select...
journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
doi：10.1007/s11274-015-1810-9
更新日期：2015-04-01 00:00:00
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章,评审
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journal_title：World journal of microbiology & biotechnology
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journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章,评审
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更新日期：2017-03-01 00:00:00
abstract：:Silver nanoparticles (SNPs) are extensively used in many industrial and medical applications; however, the impact of their release in the environment is still considered an understudied field. In the present work, SNPs present in aqueous lab waste water (average size of 30 nm) were used to determine their impact on mi...
journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
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更新日期：2014-06-01 00:00:00
abstract：:When 50MM FeSO4 was added to cow dung and poultry litter waste which had been processed in daily-fed batch digesters, digesters subsequently unfed showed a faster conversion of substrate and overloaded digesters stabilized within 48 h. Early stabilization of digesters was achieved by adding 20 or 50MM FeSO4 though the...
journal_title：World journal of microbiology & biotechnology
pub_type： 杂志文章
doi：10.1007/BF00360890
更新日期：1994-03-01 00:00:00
