Short communication: new HIV infections at Southern New England academic institutions: implications for prevention.

abstract：:Monitoring HIV subtype distribution is important for understanding transmission dynamics. Subtype B has historically been dominant in Australia, but in recent years new clades have appeared. Since 2000, clade data have been collected as part of HIV surveillance in South Australia. The aim of this study was to evaluate...

journal_title：AIDS research and human retroviruses

authors： Hawke KG,Waddell RG,Gordon DL,Ratcliff RM,Ward PR,Kaldor JM

更新日期：2013-02-01 00:00:00

abstract：:Despite the availability of antiretroviral therapy (ART), HIV-infected drug users, particularly crack cocaine users, continue to have high HIV-related morbidity and mortality. We conducted a cross-sectional analysis of the baseline data for hospitalized HIV-infected crack cocaine users recruited for Project HOPE (Hosp...

journal_title：AIDS research and human retroviruses

authors： Doshi RK,Vogenthaler NS,Lewis S,Rodriguez A,Metsch L,del Rio C

更新日期：2012-09-01 00:00:00

abstract：:Direct evidence confirming the hypothesis that a dysfunction of the mitochondrial respiratory chain (MRC) underlies the pathogenesis of hyperlactatemia associated with highly active antiretroviral therapy (HAART) is scarce. We studied mitochondrial DNA (mtDNA) content and MRC function in the skeletal muscle of an HIV-...

journal_title：AIDS research and human retroviruses

authors： Miró O,López S,Martínez E,Rodríguez-Santiago B,Blanco JL,Milinkovic A,Miró JM,Nunes V,Casademont J,Gatell JM,Cardellach F

更新日期：2003-11-01 00:00:00

abstract：:HLA is one of the genetic factors that influence the clinical course of HIV-1 infection, and patients with HLA-B35 are prone to rapid disease progression. Nine viral epitopes that are recognized by cytotoxic T lymphocytes (CTLs) in an HLA-B35-restricted manner were determined. To examine how HIV-1 sequences are select...

journal_title：AIDS research and human retroviruses

authors： Kawana A,Tomiyama H,Takiguchi M,Shioda T,Nakamura T,Iwamoto A

更新日期：1999-08-10 00:00:00

abstract：:Membrane-interactive phospholipids (PLs), previously evaluated for activity against HIV-1 in vitro, are known to affect late steps in viral replication. Studies were done to determine the effects of PL analogs on post-translational processing of HIV-1 proteins, binding of viral surface gp160/gp120 to CD4 receptor, and...

journal_title：AIDS research and human retroviruses

authors： Krugner-Higby L,Goff D,Edwards T,Iyer N,Neufeld J,Kute T,Morris-Natschke S,Ishaq K,Piantadosi C,Kucera LS

更新日期：1995-06-01 00:00:00

abstract：:Enrolling and tracking cohorts for HIV vaccine efficacy trials requires that participants disclose behaviors that place them at risk for exposure to HIV. Brief screening procedures have been suggested for this purpose. In a previous study gay and bisexual men in three U.S. cities reported unprotected anal intercourse ...

journal_title：AIDS research and human retroviruses

authors： McKirnan DJ,Doetsch J,Vanable P,Buchbinder S,Douglas JM,Judson F

更新日期：1994-01-01 00:00:00

abstract：:We studied the ability of several polyionic compounds, previously shown to have activity in vitro against human immunodeficiency virus (anti-HIV) to block binding of anti-CD4 and recombinant HIV gp120 to the CD4 receptor on human lymphocytes. We found that Evans blue and aurin tricarboxylic acid could completely inhib...

journal_title：AIDS research and human retroviruses

authors： Weaver JL,Gergely P,Pine PS,Patzer E,Aszalos A

更新日期：1990-09-01 00:00:00

abstract：:HIV antigens were detected by immunoelectron microscopy at the surface of human and simian T4 lymphocytes that had been infected in vitro. HIV antigens were detected at the surface of cells exhibiting viral particles but also at the surface of cells before the release of virions. The latter cells may be considered imm...

journal_title：AIDS research and human retroviruses

authors： Desportes I,Bonnet D,Nicol I,Snart R,Sarin P

更新日期：1989-02-01 00:00:00

abstract：:The incidence of anal cancer is increased in HIV-infected patients compared with the general population. Risk factors associated with the anal cancer precursor, high-grade squamous intraepithelial lesion (HSIL), have not been extensively studied in an urban black population with late-stage HIV disease. We performed a ...

journal_title：AIDS research and human retroviruses

authors： Frank M,Lahiri CD,Nguyen ML,Mehta CC,Mosunjac M,Flowers L

更新日期：2018-07-01 00:00:00

abstract：:HIV prevalence in the Limpopo Province has increased rapidly within the past 10 years, as in other parts of South Africa. Little is known about the genetic and biological properties of HIV circulating in this region including the baseline drug resistance profiles. We therefore collected blood samples from 42 HIV-1-inf...

journal_title：AIDS research and human retroviruses

authors： Bessong PO,Larry Obi C,Cilliers T,Choge I,Phoswa M,Pillay C,Papathanasopoulos M,Morris L

更新日期：2005-01-01 00:00:00

abstract：:In this study, HIV strains circulating among military personnel were characterized, in Malabo, the capital city of Equatorial Guinea. One sample was found to be HIV-2 group A while a high degree of genetic diversity was recorded in the pol region of 41 HIV-1-positive samples. CRF02_AG accounted for 53.7% of the strain...

journal_title：AIDS research and human retroviruses

authors： Djoko CF,Wolfe ND,Vidal N,Tamoufe U,Montavon C,LeBreton M,Pike BL,Fair J,Mbacham WF,Benito A,Rimoin AW,Saylors K,Mpoudi-Ngole E,Grillo MP,Peeters M

更新日期：2010-09-01 00:00:00

abstract：:We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥20...

journal_title：AIDS research and human retroviruses

authors： Roca B,Spanish VACH Cohort Group.

更新日期：2020-11-01 00:00:00

abstract：:We studied the phylogeny of HIV-1 subtype F viruses from children and adults in Romania in order to (1) clarify whether the Romanian subtype F epidemic was caused by one or several virus introductions and (2) gain insight into the route of spread of the HIV-1 subtype F virus among children and adults in Romania. env (...

journal_title：AIDS research and human retroviruses

authors： Op De Coul E,van den Burg R,Asjö B,Goudsmit J,Cupsa A,Pascu R,Usein C,Cornelissen M

更新日期：2000-03-01 00:00:00

abstract：:All-trans-retinoic acid (RA) has been shown either to activate or repress human immunodeficiency virus type 1 (HIV-1) replication in primary monocyte-derived-macrophages (MDMs). We systematically investigated the contribution that cell donor and virus differences make to this variability. We found that the effect of R...

journal_title：AIDS research and human retroviruses

authors： Brown XQ,Hanley TM,Viglianti GA

更新日期：2002-06-10 00:00:00

abstract：:We have used a panel of anti-gp160 MAbs to construct anti-HIV immunotoxins by coupling antibodies to ricin A chain (RAC). The ability of the immunotoxins to kill HIV-1-infected cells and halt the spread of infection was tested in tissue culture on persistently and acutely infected cell lines and primary lymphocyte cul...

journal_title：AIDS research and human retroviruses

authors： Pincus SH,Wehrly K,Cole R,Fang H,Lewis GK,McClure J,Conley AJ,Wahren B,Posner MR,Notkins AL,Tilley SA,Pinter A,Eiden L,Teintze M,Dorward D,Tolstikov VV

更新日期：1996-07-20 00:00:00

abstract：:Interferon-α (IFN-α) plays a vital role in combating viral infections especially in the early control after infection. However, the HIV infection has shown substantial level of suppression of IFN-α secretion during initial phase of infection. The reasons behind this impairment are still obscure. As plasmacytoid dendri...

journal_title：AIDS research and human retroviruses

authors： Dhamanage AS,Thakar MR,Paranjape RS

更新日期：2019-01-01 00:00:00

abstract：:Mucosal candidiasis is a common complication of HIV infection and HIV-positive women may develop both oropharyngeal and vaginal disease. Colonization with Candida albicans and related species at either site is a common preceding event in asymptomatic women. To examine the molecular epidemiology of colonizing yeast str...

journal_title：AIDS research and human retroviruses

authors： Dahl KM,Keath EJ,Fraser VJ,Powderly WG

更新日期：1997-04-10 00:00:00

abstract：:Maraviroc (MVC) is licensed in clinical practice for patients with R5 virus and virological failure; however, in anecdotal reports, dual/mixed viruses were also inhibited. We retrospectively evaluated the evolution of HIV-1 coreceptor tropism in plasma and peripheral blood mononuclear cells (PBMCs) of an infected adol...

journal_title：AIDS research and human retroviruses

authors： Cavarelli M,Mainetti L,Pignataro AR,Bigoloni A,Tolazzi M,Galli A,Nozza S,Castagna A,Sampaolo M,Boeri E,Scarlatti G

更新日期：2014-12-01 00:00:00

abstract：:The full-length RNA of human immunodeficiency virus type 1 (HIV-1) serves both as a messenger (mRNA) to direct the translation of Pr55(gag) proteins and as genomic or viral particle RNA (vpRNA) to be packaged into virions. In this study, we have assessed a putative cis-acting effect of Pr55(gag) translation on HIV-1 R...

journal_title：AIDS research and human retroviruses

authors： Liang C,Hu J,Russell RS,Wainberg MA

更新日期：2002-10-10 00:00:00

abstract：:We have studied a woman with transfusion-acquired HIV who appears to have contained infectious virus to consistently undetectable levels over a 13-year period without antiviral treatment. She received the infected transfusion for intra- and postpartum blood loss immediately after delivery of her second child in 1981. ...

journal_title：AIDS research and human retroviruses

authors： Schwartz D,Sharma U,Busch M,Weinhold K,Matthews T,Lieberman J,Birx D,Farzedagen H,Margolick J,Quinn T

更新日期：1994-12-01 00:00:00

abstract：:Infection with human T lymphotropic virus (HTLV), although asymptomatic in most cases, can lead to severe illnesses, such as adult T cell leukemia/lymphoma or myelopathy/tropical spastic paraparesis. HTLV can be transmitted by whole-blood (WB) transfusion. The prevalence of HTLV among blood donor populations has not b...

journal_title：AIDS research and human retroviruses

authors： Pham D,Nguyen D,Nguyen TA,Tran C,Tran L,Devare S,Tran A,Bhatnagar S

更新日期：2019-04-01 00:00:00

abstract：:In order to further characterize the interaction of human immunodeficiency viruses (HIV) with the CD4 receptor at the molecular level, a binding test was performed using iodine-labeled glycoproteins, 125I-gp160 from HIV-1 and 125I-gp140 from HIV-2, to bind to lymphoid cells expressing the CD4 receptor. The inhibition ...

journal_title：AIDS research and human retroviruses

authors： Bahraoui E,Benjouad A,Guetard D,Kolbe H,Gluckman JC,Montagnier L

更新日期：1992-05-01 00:00:00

abstract：:Older HIV-positive patients may experience reduced benefit and increased toxicities from combination antiretroviral therapies (cART) due to late diagnosis, weakened immune systems, and other age-related physiological changes. This study investigates the effect of age on time to virologic suppression and CD4 cell count...

journal_title：AIDS research and human retroviruses

authors： Szadkowski L,Tseng A,Walmsley SL,Salit I,Raboud JM

更新日期：2012-12-01 00:00:00

abstract：:The aim of this study was to compare the extent of resistance to antiretroviral (ARV) drugs among the population in Mexico before and after 2005. The mutations and drug resistance database of Stanford University were used for analyzing drug resistance tests that had been performed on HIV treatment-naive patients. The ...

journal_title：AIDS research and human retroviruses

authors： Escoto-Delgadillo M,Torres-Mendoza BM,Flores-Soto M,Vazquez-Valls E

更新日期：2016-12-01 00:00:00

abstract：:A sharp increase in the number of people living with HIV has been documented in the Philippines. In response, the government has instituted antiretroviral therapy (ART) nationwide through HIV treatment hubs. However, no data presently exist on the status of ART drug-resistance-associated mutations (DRMs). In this stud...

journal_title：AIDS research and human retroviruses

authors： SahBandar IN,Samonte G,Telan E,Siripong N,Belcaid M,Schanzenbach D,Leano S,Chagan-Yasutan H,Hattori T,Shikuma CM,Ndhlovu LC

更新日期：2017-11-01 00:00:00

abstract：:Jurkat cells stably expressing high levels of the HIV-1 Tat protein were generated after transfection with an Epstein-Barr virus-based episomal replicon and selection in hygromycin B. The Jurkat Tat transfectants exhibited a longer doubling time when compared to Jurkat cells or Jurkat cells transfected with the contro...

journal_title：AIDS research and human retroviruses

authors： Purvis SF,Jacobberger JW,Sramkoski RM,Patki AH,Lederman MM

更新日期：1995-04-01 00:00:00

abstract：:Sequences from the nef/LTR overlap region of the human immunodeficiency virus type 2 (HIV-2) genome were amplified from uncultured peripheral blood mononuclear cells (PBMCs) from 40 HIV-2-infected individuals in The Gambia, West Africa. Additional sequences from the plasma of three blood donors were also derived. Anal...

journal_title：AIDS research and human retroviruses

authors： Berry N,Ariyoshi K,Balfe P,Tedder R,Whittle H

更新日期：2001-02-10 00:00:00

abstract：:Studies of HIV molecular evolution and pathogenesis have relied on the polymerase chain reaction (PCR) to provide sequence information from infected tissues. Until recently, studies have been constrained by the limited length of fragments that can be reliably amplified. The addition of a thermostable 3'-exonuclease ac...

journal_title：AIDS research and human retroviruses

authors： Yang YL,Wang G,Dorman K,Kaplan AH

更新日期：1996-03-01 00:00:00

abstract：:DNA of a recently described fifth exogenous retrovirus (HRV-5) has been found in blood samples from patients with autoimmune diseases and lymphoma. We analyzed HRV-5 sequence in DNA extracted from whole blood of 17 patients with T cell non-Hodgkin's lymphoma (NHL) and 186 patients with hematological malignancies other...

journal_title：AIDS research and human retroviruses

authors： Kozireva S,Lejniece S,Blomberg J,Murovska M

更新日期：2001-07-01 00:00:00

abstract：:Given the rising HIV incidence in men who have sex with men (MSM) despite repeatedly proven effectiveness of oral HIV pre-exposure prophylaxis, behaviorally congruent periodic dosing strategies, such as dosing microbicides as lubricants, are now in demand. Rectal microbicide gel studies largely administer gels using v...

journal_title：AIDS research and human retroviruses

authors： Shieh EC,Weld ED,Fuchs EJ,Hiruy H,Buckheit KW,Buckheit RW Jr,Breakey J,Hendrix CW

更新日期：2017-08-01 00:00:00