Incorporation of HLA antigens into the envelope of RNA tumor viruses grown in human cells.

Abstract:

:Virion antigens of feline leukemia virus are associated with HLA antigens in the membrane of human cells infected with the virus. Feline leukemia virus produced by these cells incorporates host membrane antigens into the virion envelope, making the virus susceptible to lysis by antisera directed to HLA or to uninfected cells plus complement.

journal_name

Cancer Res

journal_title

Cancer research

authors

Azocar J,Essex M

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

3388-91

issue

9

eissn

0008-5472

issn

1538-7445

journal_volume

39

pub_type

杂志文章
  • Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP).

    abstract::Latent prostate tumors are commonly found with similar frequency in many countries and ethnic groups. In contrast, aggressive prostate cancer (PC) is significantly less prevalent among Asian men, where the intake of soy products is very high. High consumption of foods containing soy results in high plasma, urine, and ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Mentor-Marcel R,Lamartiniere CA,Eltoum IE,Greenberg NM,Elgavish A

    更新日期:2001-09-15 00:00:00

  • Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.

    abstract::Overexpression of cyclin D1 is believed to endow mammary epithelial cells (MEC) with a proliferative advantage by virtue of its contribution to pRB inactivation. Accordingly, abrogation of the kinase-dependent function of cyclin D1 is sufficient to render mice resistant to breast cancer initiated by ErbB2. Here, we re...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-11-4139

    authors: Brown NE,Jeselsohn R,Bihani T,Hu MG,Foltopoulou P,Kuperwasser C,Hinds PW

    更新日期:2012-12-15 00:00:00

  • Parameters affecting tumor-specific delivery of anti-CD5 antibody-ricin A chain immunotoxins in vivo.

    abstract::The tumor localization of various anti-CD5 immunotoxins (ITs) was studied in vivo in BALB/c nude mice bearing human ascitic Ichikawa tumor cells. Plasma and ascitic clearance of IT as well as the number of intact IT molecules taken up per tumor cell was measured with a highly sensitive immunoenzymometric assay. This a...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Rostaing-Capaillon O,Casellas P

    更新日期:1990-05-15 00:00:00

  • Androgen dependency of a tumor produced by a cell line derived from androgen-responsive Shionogi carcinoma 115.

    abstract::An androgen-dependent tumor (SCC8 tumor) was obtained by inoculating an androgen-responsive cell line derived from the androgen-responsive Shionogi carcinoma 115 (SC115) into mice and then treating the mice with testosterone propionate (TP) at a pharmacological dose (400 micrograms/day). The SCC8 tumor differed in his...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Terada N,Yamamoto R,Uchida N,Takada T,Taniguchi H,Takatsuka D,Sawada M,Tsuji M,Li W,Kitamura Y

    更新日期:1989-02-01 00:00:00

  • Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer.

    abstract::The deregulated expression of cyclin E as measured by the overexpression of its low molecular weight (LMW) isoforms is a powerful predictor of poor outcome in patients with breast cancer. The mechanism by which these LMW forms give tumor cells a growth advantage is not known and is the subject of this article. In this...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.can-03-3672

    authors: Akli S,Zheng PJ,Multani AS,Wingate HF,Pathak S,Zhang N,Tucker SL,Chang S,Keyomarsi K

    更新日期:2004-05-01 00:00:00

  • Expression of the O6-methylguanine-DNA methyltransferase gene MGMT in MER+ and MER- human tumor cells.

    abstract::DNA probes prepared from human O6-methylguanine-DNA methyltransferase complementary DNA were hybridized to mRNA isolated from human liver and fifteen human tumor cell lines proficient (Mer+) or deficient (Mer-) in transferase activity. Liver and Mer+ cells contained levels of transferase-specific mRNA that correlated ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Fornace AJ Jr,Papathanasiou MA,Hollander MC,Yarosh DB

    更新日期:1990-12-15 00:00:00

  • Genetic variants in oxidative stress-related genes predict chemoresistance in primary breast cancer: a prospective observational study and validation.

    abstract::Chemotherapy response in patients with primary breast cancer is difficult to predict and the role of host genetic factors has not been thoroughly investigated. We hypothesized that polymorphisms in oxidative stress (OS)-related genes, including estrogen-quinone metabolizing enzymes NQO2 and GSTM1-5, may influence dise...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-11-2998

    authors: Yu KD,Huang AJ,Fan L,Li WF,Shao ZM

    更新日期:2012-01-15 00:00:00

  • Protein kinase C delta involvement in mammary tumor cell metastasis.

    abstract::Metastasis requires cytoskeletal remodeling for migration, adhesion, and extravasation of metastatic cells. Although protein kinase C (PKC) is involved in tumor promotion/progression and cytoskeletal remodeling, its role in metastasis has not been defined. PKCdelta levels are increased in highly metastatic 13762NF mam...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Kiley SC,Clark KJ,Goodnough M,Welch DR,Jaken S

    更新日期:1999-07-01 00:00:00

  • HER-2/neu amplification predicts poor survival in node-positive breast cancer.

    abstract::HER-2/neu protooncogene amplification and protein expression were analyzed with slot blot and Western blot techniques, respectively, in more than 300 invasive primary breast tumors of all stages. Amplification (2- greater than 30 copies) was found in 17% of these tumors and high expression was seen in 19%. There was a...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Borg A,Tandon AK,Sigurdsson H,Clark GM,Fernö M,Fuqua SA,Killander D,McGuire WL

    更新日期:1990-07-15 00:00:00

  • Antibody microarray profiling reveals individual and combined serum proteins associated with pancreatic cancer.

    abstract::We used antibody microarrays to probe the associations of multiple serum proteins with pancreatic cancer and to explore the use of combined measurements for sample classification. Serum samples from pancreatic cancer patients (n = 61), patients with benign pancreatic disease (n = 31), and healthy control subjects (n =...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-05-1436

    authors: Orchekowski R,Hamelinck D,Li L,Gliwa E,vanBrocklin M,Marrero JA,Vande Woude GF,Feng Z,Brand R,Haab BB

    更新日期:2005-12-01 00:00:00

  • Mimicry of bryostatin 1 induced phosphorylation patterns in HL-60 cells by high-phorbol ester concentrations.

    abstract::The bryostatins are a group of macrocyclic lactones isolated from the marine bryozoan Bugula neritina. Bryostatin 1, like the phorbol esters, activates protein kinase C; however, it partially inhibits the phorbol ester induced differentiation of the human promyelocytic leukemic cell line HL-60. We compared the phospho...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Warren BS,Kamano Y,Pettit GR,Blumberg PM

    更新日期:1988-11-01 00:00:00

  • The effect of exposure to dibutyryl cyclic adenylic acid on the membrane antigenicity of SV40 tumor cells.

    abstract::When SV40 tumor cells (F5-1) in culture were treated with dibutyryl cyclic adenylic acid (DbcAMP),marked alterations occurred in their growth and morphology. Additionally, the incorporation or uptake of labeled thymidine, uridine, phenylalanine, and choline were reduced by this treatment. These modifications with DbcA...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Hannon WH,Anderson NG,Coggin JH Jr

    更新日期:1976-09-01 00:00:00

  • Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line.

    abstract::The regulation of urokinase secretion and receptor display in a well-differentiated colon carcinoma cell line, GEO, adapted to serum-free conditions was examined. In protein-free medium, the cell line secreted 0.8 +/- 0.1 ng/ml/10(6) cells of urokinase in a 3-day period as determined by an enzyme-linked immunosorbent ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Boyd D,Brattain M

    更新日期:1989-04-15 00:00:00

  • The cytotoxicity of gamma-L-glutaminyl-4-hydroxybenzene for cells that contain tyrosinase, a study of melanocytes in the hair follicle of the mouse.

    abstract::The s.c. administration of gamma-L-glutaminyl-4-hydroxybenzene (GHB) to neonatal black mice produced a prompt, generalized, and selective swelling and lysis of the melanocytes of the hair follicles. The findings indicate that this cytotoxic effect was dependent upon the intracellular activation of GHB by tyrosinase. S...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Burger PC,Kemper LA,Vogel FS

    更新日期:1979-05-01 00:00:00

  • Immunohistochemical evidence of urokinase-type plasminogen activator in primary and metastatic tumors of pulmonary adenocarcinoma.

    abstract::The urokinase-type plasminogen activator (u-PA) was used to study 96 cases of lung adenocarcinoma and 49 cases of lymph node metastatic adenocarcinoma. We made use of the immunohistochemistry of paraffinized samples. u-PA was detected in the cytoplasm of tumor cells, and the number of positive cells was higher in pati...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Oka T,Ishida T,Nishino T,Sugimachi K

    更新日期:1991-07-01 00:00:00

  • Aurora-A regulation of nuclear factor-kappaB signaling by phosphorylation of IkappaBalpha.

    abstract::The Aurora-A/STK15 gene encodes a kinase that is frequently amplified in cancer. Overexpression of Aurora-A in mammalian cells leads to centrosome amplification, genetic instability, and transformation. In this study, we show that Aurora-A activates nuclear factor-kappaB (NF-kappaB) via IkappaBalpha phosphorylation. I...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-06-2272

    authors: Briassouli P,Chan F,Savage K,Reis-Filho JS,Linardopoulos S

    更新日期:2007-02-15 00:00:00

  • Boron neutron capture therapy: boron biodistribution and pharmacokinetics of Na2B12H11SH in patients with glioblastoma.

    abstract::Data on biodistribution and pharmacokinetics of Na2B12H11SH are few and lack in standardization. This study comprises a uniform series of 10 patients with glioblastoma administered Na2B12H11SH i.v. 24 h before surgery at a dose level used in earlier therapeutical trials (75 mg/kg body weight). Boron concentrations in ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Haselsberger K,Radner H,Pendl G

    更新日期:1994-12-15 00:00:00

  • Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.

    abstract::5'-Deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine, which are metabolized to the methionine precursor, 5-methylthioribose-1-phosphate, by 5'-deoxy-5'-methylthioadenosine phosphorylase and purine nucleoside phosphorylase, respectively, can serve as sources of methionine for cultured HL-60 promyelocytic l...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Savarese TM,Ghoda LY,Dexter DL,Parks RE Jr

    更新日期:1983-10-01 00:00:00

  • Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.

    abstract::The effects of tumor-promoting phorbol diesters on ornithine decarboxyalse (ODC) activity and DNA synthesis in normal and chemically transformed hamster embryo fibroblasts (HEF) in culture were studied. Only those phorbol diesters with promoting activity in mouse skin induced ODC in HEF. ODC was induced in both cell t...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: O'Brien TG,Diamond L

    更新日期:1977-11-01 00:00:00

  • Characterization by molecular hybridization of two viral populations derived from a radiation leukemia virus.

    abstract::Two leukemogenic viral populations were derived from a radiation leukemia virus of the C57BL mouse. One (FB), in which only B-tropic virus could be detected, was obtained in vivo by serial passage of cell-free extract in newborn rats. The second (3C), a complex containing at least B-tropic and xenotropic viruses, was ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Janowski M,Astier T,Guillemain B,Baugnet-Mahieu L,Duplan JF,Maisin JR

    更新日期:1978-10-01 00:00:00

  • Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy.

    abstract::Osteoprotegerin (OPG), a novel, secreted tumor necrosis factor receptor family member that inhibits osteoclast formation and activity was examined for its activity in a syngeneic tumor model of humoral hypercalcemia of malignancy. Normal mice bearing Colon-26 tumors develop increases in both parathyroid hormone-relate...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Capparelli C,Kostenuik PJ,Morony S,Starnes C,Weimann B,Van G,Scully S,Qi M,Lacey DL,Dunstan CR

    更新日期:2000-02-15 00:00:00

  • The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells.

    abstract::The clinically relevant polyamine analogue N(1),N(11)-diethylnorspermine (DENSPM) inhibits cell growth by down-regulating polyamine biosynthesis, up-regulating polyamine catabolism at the level of spermidine/spermine N(1)-acetyltransferase (SSAT), and depleting intracellular polyamine pools. Among human melanoma cell ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Chen Y,Alm K,Vujcic S,Kramer DL,Kee K,Diegelman P,Porter CW

    更新日期:2003-07-01 00:00:00

  • Expression of endogenous murine leukemia virus in transplantable tumor cells and DNA methylation of the viral sequences.

    abstract::A cell line derived from early passage of a transplantable tumor in athymic mice that initially had been injected with human breast adenocarcinoma cells produced a substantial amount of RNA sequences related to the Kirsten murine leukemia virus. The cell line derived from later passage of transplantation of these tumo...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Kuo MT,Sen S,Teeter L,Cailleau RM,Knesek JE,Bowen J

    更新日期:1984-08-01 00:00:00

  • Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.

    abstract::Genome-wide association studies (GWAS) of bladder cancer have identified a number of susceptibility loci in European populations but have yet to uncover the genetic determinants underlying bladder cancer incidence among other ethnicities. Therefore, we performed the first GWAS in a Chinese cohort comprising 3,406 case...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-15-2564

    authors: Wang M,Li Z,Chu H,Lv Q,Ye D,Ding Q,Xu C,Guo J,Du M,Chen J,Song Z,Yin C,Qin C,Gu C,Zhu Y,Xia G,Liu F,Zhang Z,Yuan L,Fu G,Hu Z,Tong N,Shen J,Liu K,Sun J,Sun Y,Li J,Li X,Shen H,Xu J,Shi Y,Zhang

    更新日期:2016-06-01 00:00:00

  • Nickel distribution and DNA lesions induced in rat tissues by the carcinogen nickel carbonate.

    abstract::DNA lesions in nuclei isolated from rat tissues following i.p. injection of the carcinogen nickel carbonate were measured by the alkaline elution technique. Kidney, liver, lung, and thymus gland nuclei were examined at 3 and 20 hr after treatment for the presence of DNA single-strand breaks and cross-links. Single-str...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Ciccarelli RB,Wetterhahn KE

    更新日期:1982-09-01 00:00:00

  • Heterotopic urinary bladder with a communicating reservoir.

    abstract::A heterotopic bladder attached to an Ommaya reservoir was transplanted to the back of a syngeneic rat. Following transplantation, the mucosa underwent ischemic necrosis. However, it was rapidly reepithelialized in 2 weeks as a result of spreading of the epithelium originating from the ureterotrigonal region. By light ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Oyasu R,Manning DJ,Matsumoto M,Hopp ML

    更新日期:1976-07-01 00:00:00

  • ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells.

    abstract::Pancreatic ductal adenocarcinoma (PDAC) is characterized by therapeutic resistance for which the basis is poorly understood. Here, we report that the DNA and p53-binding protein ATDC/TRIM29, which is highly expressed in PDAC, plays a critical role in DNA damage signaling and radioresistance in pancreatic cancer cells....

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-13-2289

    authors: Wang L,Yang H,Palmbos PL,Ney G,Detzler TA,Coleman D,Leflein J,Davis M,Zhang M,Tang W,Hicks JK,Helchowski CM,Prasad J,Lawrence TS,Xu L,Yu X,Canman CE,Ljungman M,Simeone DM

    更新日期:2014-03-15 00:00:00

  • Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells.

    abstract::Brain invasion by glioblastoma determines prognosis, recurrence, and lethality in patients, but no master factor coordinating the invasive properties of glioblastoma has been identified. Here we report evidence favoring such a role for the noncanonical WNT family member Wnt5a. We found the most invasive gliomas to be ...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-16-1693

    authors: Binda E,Visioli A,Giani F,Trivieri N,Palumbo O,Restelli S,Dezi F,Mazza T,Fusilli C,Legnani F,Carella M,Di Meco F,Duggal R,Vescovi AL

    更新日期:2017-02-15 00:00:00

  • Interaction of benzo(a)pyrene and its dihydrodiol-epoxide derivative with nuclear and mitochondrial DNA in C3H10T 1/2 cell cultures.

    abstract::To analyze the distribution of radioactive carcinogens and [3H]thymidine between nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), we have developed a simple and rapid method for the separation of nDNA and mtDNA using gel electrophoresis of cell lysates. Using this method, we found that, when C3H10T 1/2 cells are expo...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:

    authors: Backer JM,Weinstein IB

    更新日期:1982-07-01 00:00:00

  • Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice.

    abstract::Helicobacter pylori-induced gastritis is the strongest singular risk factor for gastric adenocarcinoma. Matrix metalloproteinase-7 (MMP-7) is a proteolytic enzyme that can modify the intestinal microbial replicative niche as well as affect tumorigenesis, and H. pylori stimulates expression of MMP-7 in gastric epitheli...

    journal_title:Cancer research

    pub_type: 杂志文章

    doi:10.1158/0008-5472.CAN-09-2899

    authors: Ogden SR,Noto JM,Allen SS,Patel DA,Romero-Gallo J,Washington MK,Fingleton B,Israel DA,Lewis ND,Wilson KT,Chaturvedi R,Zhao Z,Shyr Y,Peek RM Jr

    更新日期:2010-01-01 00:00:00