Expression of endogenous murine leukemia virus in transplantable tumor cells and DNA methylation of the viral sequences.

Abstract:

:A cell line derived from early passage of a transplantable tumor in athymic mice that initially had been injected with human breast adenocarcinoma cells produced a substantial amount of RNA sequences related to the Kirsten murine leukemia virus. The cell line derived from later passage of transplantation of these tumors diminished viral RNA production. Expression of the viral RNA sequences in these cell lines is inversely correlated with the level of viral DNA methylation in the mouse genome.

journal_name

Cancer Res

journal_title

Cancer research

authors

Kuo MT,Sen S,Teeter L,Cailleau RM,Knesek JE,Bowen J

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

3518-21

issue

8

eissn

0008-5472

issn

1538-7445

journal_volume

44

pub_type

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