Effects of brief coronary occlusion and reperfusion on porcine coronary artery reactivity.

abstract：BACKGROUND:To explore roles of endogenous atrial natriuretic peptide (ANP) in blood pressure and volume regulation, we examined the effects of a newly developed ANP antagonist, HS-142-1 (HS) in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. METHODS AND RESULTS:We examined 1) the effects of HS on ANP- or br...

journal_title：Circulation

authors： Hirata Y,Matsuoka H,Suzuki E,Hayakawa H,Sugimoto T,Matsuda Y,Morishita Y,Kangawa K,Minamino N,Matsuo H

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the left ventricle. This study aimed to evaluate whether left ventricular unloading in patients with cardiogenic shock treated wit...

journal_title：Circulation

authors： Schrage B,Becher PM,Bernhardt A,Bezerra H,Blankenberg S,Brunner S,Colson P,Cudemus Deseda G,Dabboura S,Eckner D,Eden M,Eitel I,Frank D,Frey N,Funamoto M,Goßling A,Graf T,Hagl C,Kirchhof P,Kupka D,Landmesser U,Li

更新日期：2020-12-01 00:00:00

abstract：:Background: In ISCHEMIA, an initial invasive strategy did not significantly reduce rates of cardiovascular events or all-cause mortality compared with a conservative strategy in patients with stable ischemic heart disease and moderate/severe myocardial ischemia. The most frequent component of composite cardiovascular ...

journal_title：Circulation

authors： Chaitman BR,Alexander KP,Cyr DD,Berger JS,Reynolds HR,Bangalore S,Boden WE,Lopes RD,Demkow M,Perna GP,Riezebos RK,McFalls EO,Banerjee S,Bagai A,Gosselin G,O'Brien SM,Rockhold FW,Waters DD,Thygesen KA,Stone GW,Whit

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:The wide range of clinical presentation of orthostatic vasovagal syncope suggests different underlying changes in the cardiac autonomic modulation. METHODS AND RESULTS:To evaluate the beat-by-beat modifications in the neural control of heart period preceding a syncopal event, we studied RR interval variabil...

journal_title：Circulation

authors： Furlan R,Piazza S,Dell'Orto S,Barbic F,Bianchi A,Mainardi L,Cerutti S,Pagani M,Malliani A

更新日期：1998-10-27 00:00:00

abstract：:The Academic Research Consortium (ARC)-2 initiative revisited the clinical and angiographic end point definitions in coronary device trials, proposed in 2007, to make them more suitable for use in clinical trials that include increasingly complex lesion and patient populations and incorporate novel devices such as bio...

journal_title：Circulation

authors： Garcia-Garcia HM,McFadden EP,Farb A,Mehran R,Stone GW,Spertus J,Onuma Y,Morel MA,van Es GA,Zuckerman B,Fearon WF,Taggart D,Kappetein AP,Krucoff MW,Vranckx P,Windecker S,Cutlip D,Serruys PW,Academic Research Consortium

更新日期：2018-06-12 00:00:00

abstract：BACKGROUND:Identification of genes that are specifically activated in restenosis lesions after percutaneous transluminal angioplasty represents a necessary step toward molecular manipulation designed to inhibit cellular proliferation responsible for such lesions. Whereas quiescent smooth muscle cells (contractile pheno...

journal_title：Circulation

authors： Leclerc G,Isner JM,Kearney M,Simons M,Safian RD,Baim DS,Weir L

更新日期：1992-02-01 00:00:00

abstract：:We assessed the reversibility of functional and morphological changes of arterialized vein segments by returning them to the venous circulation. Thirteen dogs underwent right carotid and femoral veno-arterial grafting. After 12 weeks, veno-arterial grafts were removed for contractility (norepinephrine [NE] and 5-hydro...

journal_title：Circulation

authors： Fann JI,Sokoloff MH,Sarris GE,Yun KL,Kosek JC,Miller DC

更新日期：1990-11-01 00:00:00

abstract：:The aim of this policy statement is to provide a comprehensive review of the scientific evidence evaluating the use of telemedicine in cardiovascular and stroke care and to provide consensus policy suggestions. We evaluate the effectiveness of telehealth in advancing healthcare quality, identify legal and regulatory b...

journal_title：Circulation

authors： Schwamm LH,Chumbler N,Brown E,Fonarow GC,Berube D,Nystrom K,Suter R,Zavala M,Polsky D,Radhakrishnan K,Lacktman N,Horton K,Malcarney MB,Halamka J,Tiner AC,American Heart Association Advocacy Coordinating Committee.

更新日期：2017-02-14 00:00:00

abstract：:We recorded direct-current extracellular electrograms simultaneously from 60 left ventricular epicardial sites in 38 alpha-chloralose-anesthetized dogs during repeated, 5 min coronary arterial occlusions. In each dog recordings made during control occlusions were compared with those made in occlusions after, or during...

journal_title：Circulation

authors： Janse MJ,Schwartz PJ,Wilms-Schopman F,Peters RJ,Durrer D

更新日期：1985-09-01 00:00:00

abstract：:In patients with atrioventricular (A-V) nodal re-entrant paroxysmal supraventricular tachycardia (PSVT), atrial extrastimulus technique frequently reveals discontinuous A1-A2, H1-H2 curves suggestive of dual A-V nodal pathways. To further test the hypothesis that these curves in fact reflect dual A-V nodal pathways, a...

journal_title：Circulation

authors： Wu D,Denes P,Wyndham C,Amat-y-Leon F,Dhingra RC,Rosen KM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Clinical and experimental studies have demonstrated a major role of the renin-angiotensin system in the functional and structural changes of the large arteries in hypertension. Because genetic studies may help us to understand the mechanisms underlying the involvement of this system in arterial regulation, t...

journal_title：Circulation

authors： Benetos A,Gautier S,Ricard S,Topouchian J,Asmar R,Poirier O,Larosa E,Guize L,Safar M,Soubrier F,Cambien F

更新日期：1996-08-15 00:00:00

abstract：:A case history of a 46-year-old Negro male was presented with rheumatic aortic insufficiency, angina pectoris, and possible subacute bacterial endocarditis. While hospitalized, the patient developed angina pectoris associated with micturition. This was not accompanied by a change in blood pressure, pulse, or increase ...

journal_title：Circulation

authors： Morris JJ,McIntosh HD

更新日期：1963-01-01 00:00:00

abstract：BACKGROUND:Human salusins, related bioactive polypeptides with mitogenic effects on vascular smooth muscle cells and fibroblasts and roles in hemodynamic homeostasis, may be involved in the origin of coronary atherosclerosis. Macrophage foam cell formation, characterized by cholesterol ester accumulation, is modulated ...

journal_title：Circulation

authors： Watanabe T,Nishio K,Kanome T,Matsuyama TA,Koba S,Sakai T,Sato K,Hongo S,Nose K,Ota H,Kobayashi Y,Katagiri T,Shichiri M,Miyazaki A

更新日期：2008-02-05 00:00:00

abstract：BACKGROUND:Recent data from this laboratory indicate that pretreatment with adenosine can protect the heart against infarction via A1-receptors, but because of systemic hypotension, adenosine had to be given into the coronary circulation. METHODS AND RESULTS:In this study, we tested whether the protection could be ach...

journal_title：Circulation

authors： Thornton JD,Liu GS,Olsson RA,Downey JM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Although patients with heart failure express elevated circulating levels of tumor necrosis factor-alpha (TNF-alpha) in their peripheral circulation, the structural and functional effects of circulating levels of pathophysiologically relevant concentrations of TNF-alpha on the heart are not known. METHODS AN...

journal_title：Circulation

authors： Bozkurt B,Kribbs SB,Clubb FJ Jr,Michael LH,Didenko VV,Hornsby PJ,Seta Y,Oral H,Spinale FG,Mann DL

更新日期：1998-04-14 00:00:00

abstract：BACKGROUND:Venous coronary artery bypass grafts (CABGs) are prone to accelerated atherosclerosis. In atherosclerotic diseases, serum C-reactive protein (CRP) levels have become an important diagnostic and prognostic marker. The origin of CRP in this setting remains to be elucidated. METHODS AND RESULTS:Monoclonal anti...

journal_title：Circulation

authors： Jabs WJ,Theissing E,Nitschke M,Bechtel JF,Duchrow M,Mohamed S,Jahrbeck B,Sievers HH,Steinhoff J,Bartels C

更新日期：2003-09-23 00:00:00

abstract：BACKGROUND:Left ventricular (LV) reconstruction surgery leads to early improvement in LV function in ischemic cardiomyopathy (ICM) patients. This study was designed to evaluate the impact of mitral valve (MV) repair associated with LV reconstruction on LV function 1-year after surgery in ICM patients assessed by real-t...

journal_title：Circulation

authors： Qin JX,Shiota T,McCarthy PM,Asher CR,Hail M,Agler DA,Popović ZB,Greenberg NL,Smedira NG,Starling RC,Young JB,Thomas JD

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:Women receive less evidence-based medical care than men and have higher rates of death after acute myocardial infarction (AMI). It is unclear whether efforts undertaken to improve AMI care have mitigated these sex disparities in the current era. METHODS AND RESULTS:Using the Get With the Guidelines-Coronary...

journal_title：Circulation

authors： Jneid H,Fonarow GC,Cannon CP,Hernandez AF,Palacios IF,Maree AO,Wells Q,Bozkurt B,Labresh KA,Liang L,Hong Y,Newby LK,Fletcher G,Peterson E,Wexler L,Get With the Guidelines Steering Committee and Investigators.

更新日期：2008-12-16 00:00:00

abstract：:Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and...

journal_title：Circulation

authors： Hayes SN,Kim ESH,Saw J,Adlam D,Arslanian-Engoren C,Economy KE,Ganesh SK,Gulati R,Lindsay ME,Mieres JH,Naderi S,Shah S,Thaler DE,Tweet MS,Wood MJ,American Heart Association Council on Peripheral Vascular Disease; Council on

更新日期：2018-05-08 00:00:00

abstract：BACKGROUND:Atrial fibrillation is common in advanced heart failure, but its prognostic significance is controversial. METHODS AND RESULTS:We evaluated the relation of atrial rhythm to overall survival and sudden death in 390 consecutive advanced heart failure patients. Etiology of heart failure was coronary artery dis...

journal_title：Circulation

authors： Middlekauff HR,Stevenson WG,Stevenson LW

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:We have demonstrated that brain natriuretic peptide (BNP) is a cardiac hormone predominantly synthesized in and secreted from the ventricle. We have also reported that, compared with atrial natriuretic peptide (ANP), the plasma concentration of BNP is increased to a greater degree in patients with congestive...

journal_title：Circulation

authors： Hama N,Itoh H,Shirakami G,Nakagawa O,Suga S,Ogawa Y,Masuda I,Nakanishi K,Yoshimasa T,Hashimoto Y

更新日期：1995-09-15 00:00:00

abstract：BACKGROUND:Although metabolomic profiling offers promise for the prediction of coronary heart disease (CHD), and metabolic risk factors are more strongly associated with CHD in women than men, limited data are available for women. METHODS:We applied a liquid chromatography-tandem mass spectrometry metabolomics platfor...

journal_title：Circulation

authors： Paynter NP,Balasubramanian R,Giulianini F,Wang DD,Tinker LF,Gopal S,Deik AA,Bullock K,Pierce KA,Scott J,Martínez-González MA,Estruch R,Manson JE,Cook NR,Albert CM,Clish CB,Rexrode KM

更新日期：2018-02-20 00:00:00

abstract：:Atherosclerotic coronary artery disease is the major cause of late cardiac transplant failure secondary to silent ischemia and infarction. To increase the longevity of cardiac homografts, we performed percutaneous transluminal coronary angioplasty (PTCA) in five male patients (aged 45 +/- 7 years, mean +/- SEM); 17 le...

journal_title：Circulation

authors： Vetrovec GW,Cowley MJ,Newton CM,Lewis SA,DiSciascio G,Thompson JA,Hastillo A,Lower R,Hess M

更新日期：1988-11-01 00:00:00

abstract：:Fibrinopeptide A, platelet factor 4, beta-thromboglobulin, thromboxane B2, and 6-keto-prostaglandin F1 alpha were estimated by radioimmunoassay on venous plasma samples taken within 48 hr of admission from 16 consecutive patients with unstable angina and 15 patients with stable angina matched for clinical variables. T...

journal_title：Circulation

authors： Théroux P,Latour JG,Léger-Gauthier C,De Lara J

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The effects of lysophosphatidylcholine (LPC) on electrophysiological activities and intracellular Ca2+ concentration ([Ca2+]i) were investigated in coronary arterial smooth muscle cells (CASMCs). METHODS AND RESULTS:The patch clamp techniques and Ca2+ measurements were applied to cultured rabbit CASMCs. The...

journal_title：Circulation

authors： Terasawa K,Nakajima T,Iida H,Iwasawa K,Oonuma H,Jo T,Morita T,Nakamura F,Fujimori Y,Toyo-oka T,Nagai R

更新日期：2002-12-10 00:00:00

abstract：BACKGROUND:Little is known of the prognostic significance of mitral regurgitation (MR) on transcatheter aortic valve replacement (TAVR), the impact of TAVR on MR severity, and the variables associated with possible post-TAVR improvement in MR. We evaluated these issues in a multicenter registry of patients undergoing C...

journal_title：Circulation

authors： Bedogni F,Latib A,De Marco F,Agnifili M,Oreglia J,Pizzocri S,Latini RA,Lanotte S,Petronio AS,De Carlo M,Ettori F,Fiorina C,Poli A,Cirri S,De Servi S,Ramondo A,Tarantini G,Marzocchi A,Fiorilli R,Klugmann S,Ussia GP

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:We recently reported that sodium channel block can produce opposite effects on action potential duration (APD) and refractoriness in epicardial versus endocardial tissues of the canine ventricle. In addition, strong sodium channel current inhibition was found to cause loss of the action potential dome in epi...

journal_title：Circulation

authors： Krishnan SC,Antzelevitch C

更新日期：1993-02-01 00:00:00

abstract：:Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients wit...

journal_title：Circulation

authors： Ralston MA,Murnane MR,Kelley RE,Altschuld RA,Unverferth DV,Leier CV

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Clinical trials have demonstrated that, compared with placebo, intensive statin therapy reduces ischemia in patients with acute coronary syndromes and in patients with stable coronary artery disease. However, no studies to date have assessed intensive versus moderate statin therapy in older patients with sta...

journal_title：Circulation

authors： Deedwania P,Stone PH,Bairey Merz CN,Cosin-Aguilar J,Koylan N,Luo D,Ouyang P,Piotrowicz R,Schenck-Gustafsson K,Sellier P,Stein JH,Thompson PL,Tzivoni D

更新日期：2007-02-13 00:00:00

abstract：BACKGROUND:Sudden cardiac death (SCD) is a major cause of mortality in adults with congenital heart disease (CHD). The aim of this study was to determine the adult CHD population at risk of SCD and the clinical parameters associated with SCD. METHODS AND RESULTS:We performed a multicenter case-control study. Patients ...

journal_title：Circulation

authors： Koyak Z,Harris L,de Groot JR,Silversides CK,Oechslin EN,Bouma BJ,Budts W,Zwinderman AH,Van Gelder IC,Mulder BJ

更新日期：2012-10-16 00:00:00