Effects of unilateral stellate ganglion stimulation and ablation on electrophysiologic changes induced by acute myocardial ischemia in dogs.

abstract：:Genetic analysis can be performed to identify the molecular substrate of inherited arrhythmogenic diseases; however, the role of this information in helping the management of patients is still debated. Here, we support the view that the practical value of genetic analysis is different in the various inherited conditio...

journal_title：Circulation

authors： Priori SG,Napolitano C

更新日期：2006-02-28 00:00:00

abstract：BACKGROUND:Patients with chronic stable angina are poorly characterized in terms of biomarkers that help in the assessment of prognosis. We investigated whether plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) may be used as a prognostic marker in patients with chronic stable angina treated with co...

journal_title：Circulation

authors： Ndrepepa G,Braun S,Niemöller K,Mehilli J,von Beckerath N,von Beckerath O,Vogt W,Schömig A,Kastrati A

更新日期：2005-10-04 00:00:00

abstract：BACKGROUND:The contractile dysfunction observed in end-stage myocardial hypertrophy has at its base an abnormality in myocyte function. However, whether depressed contractile function is related to an alteration in contractile protein function is presently unknown. METHODS AND RESULTS:Contractile force, tension, and c...

journal_title：Circulation

authors： Fan D,Wannenburg T,de Tombe PP

更新日期：1997-05-06 00:00:00

abstract：:Using a high-pressure liquid chromatographic assay, we measured serum amiodarone concentrations serially in 122 patients treated with amiodarone for 1.5-53 months (mean 9.3 months) for control of refractory symptomatic atrial or symptomatic and life-threatening ventricular tachyarrhythmias. The atrial tachyarrhythmias...

journal_title：Circulation

authors： Haffajee CI,Love JC,Canada AT,Lesko LJ,Asdourian G,Alpert JS

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Altered composition of the gut microbiota is involved in both the onset and progression of obesity and diabetes mellitus. However, the link between gut microbiota and obesity-related cardiovascular complications has not been explored. The present study was designed to investigate the role of Akkermansia muci...

journal_title：Circulation

authors： Li J,Lin S,Vanhoutte PM,Woo CW,Xu A

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Nafamostat mesilate (FUT-175) is a protease inhibitor inactivating coagulation, fibrinolysis, and platelet aggregation. A prospective, randomized trial was performed to assess the efficacy of FUT-175 in the reduction of postoperative bleeding tendency. METHODS AND RESULTS:FUT-175 was infused at a rate of 40...

journal_title：Circulation

authors： Murase M,Usui A,Tomita Y,Maeda M,Koyama T,Abe T

更新日期：1993-11-01 00:00:00

abstract：:A prospective electrocardiographic study was designed to establish baseline values for electrocardiographic measurements, with specific reference to the QT interval during infancy, and to test the "QT hypothesis" for the sudden infant death syndrome (SIDS). In this ongoing study, ECGs are recorded on the fourth day of...

journal_title：Circulation

authors： Schwartz PJ,Montemerlo M,Facchini M,Salice P,Rosti D,Poggio G,Giorgetti R

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:The biological response to antiplatelet drugs has repeatedly been shown to predict the recurrence of major adverse cardiovascular events (MACEs). However, most studies involved coronary artery disease patients with recent vessel injury shortly after the initiation of antiplatelet therapy. Data on stable card...

journal_title：Circulation

authors： Reny JL,Berdagué P,Poncet A,Barazer I,Nolli S,Fabbro-Peray P,Schved JF,Bounameaux H,Mach F,de Moerloose P,Fontana P,Antiplatelet Drug Resistances and Ischemic Events (ADRIE) Study Group.

更新日期：2012-06-26 00:00:00

abstract：BACKGROUND:Little is known of the prognostic significance of mitral regurgitation (MR) on transcatheter aortic valve replacement (TAVR), the impact of TAVR on MR severity, and the variables associated with possible post-TAVR improvement in MR. We evaluated these issues in a multicenter registry of patients undergoing C...

journal_title：Circulation

authors： Bedogni F,Latib A,De Marco F,Agnifili M,Oreglia J,Pizzocri S,Latini RA,Lanotte S,Petronio AS,De Carlo M,Ettori F,Fiorina C,Poli A,Cirri S,De Servi S,Ramondo A,Tarantini G,Marzocchi A,Fiorilli R,Klugmann S,Ussia GP

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:We have demonstrated that myocardial acceleration during isovolumic contraction (IVA) is a sensitive index of right ventricular contractile function. In this study, we assessed the usefulness of IVA to measure left ventricular (LV) contractile function and force-frequency relationships in an experimental pre...

journal_title：Circulation

authors： Vogel M,Cheung MM,Li J,Kristiansen SB,Schmidt MR,White PA,Sorensen K,Redington AN

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Recent failures of drugs that raised high-density lipoprotein (HDL) cholesterol levels to reduce cardiovascular events in clinical trials have led to increased interest in alternative indices of HDL quality, such as cholesterol efflux capacity, and HDL quantity, such as HDL particle number. However, no studi...

journal_title：Circulation

authors： Khera AV,Demler OV,Adelman SJ,Collins HL,Glynn RJ,Ridker PM,Rader DJ,Mora S

更新日期：2017-06-20 00:00:00

abstract：:Retrograde coronary artery flow was observed angiographically in 43 patients with aortic stenosis and/or regurgitation. In the 24 patients with pure or predominant aortic stenosis, retrograde flow was seen in all 24 during end-systole. In the eight patients with pure aortic regurgitation, retrograde flow was seen main...

journal_title：Circulation

authors： Carroll RJ,Falsetti HL

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Recent studies of beta-adrenergic receptor (beta-AR) subtype signaling in in vitro preparations have raised doubts as to whether the cAMP/protein kinase A (PKA) signaling is activated in the same manner in response to beta2-AR versus beta1-AR stimulation. METHODS AND RESULTS:The present study compared, in t...

journal_title：Circulation

authors： Kuschel M,Zhou YY,Spurgeon HA,Bartel S,Karczewski P,Zhang SJ,Krause EG,Lakatta EG,Xiao RP

更新日期：1999-05-11 00:00:00

abstract：BACKGROUND:The role of angiotensin II receptor subtypes was investigated in focal brain ischemia induced by middle cerebral artery (MCA) occlusion. METHODS AND RESULTS:In Agtr2+ (wild-type) mice, MCA occlusion induced focal ischemia of approximately 20% to 30% of the total area in coronal section of the brain. The isc...

journal_title：Circulation

authors： Iwai M,Liu HW,Chen R,Ide A,Okamoto S,Hata R,Sakanaka M,Shiuchi T,Horiuchi M

更新日期：2004-08-17 00:00:00

abstract：:Although a family history of ischemic heart disease is a well-accepted risk factor for cardiovascular disease, only three prospective studies--all in men--have examined the predictive strength of a positive family history after adjusting for other heart disease risk factors. The present analysis is based on a 9 year f...

journal_title：Circulation

authors： Barrett-Connor E,Khaw K

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) and angiotensin II (Ang II) modulate heart failure in part by provoking the hypertrophic response. Signal transduction pathways of those factors are implicated in reactive oxygen intermediates (ROIs). Therefore, we hypothesized that TNF-alpha and Ang II might cause myo...

journal_title：Circulation

authors： Nakamura K,Fushimi K,Kouchi H,Mihara K,Miyazaki M,Ohe T,Namba M

更新日期：1998-08-25 00:00:00

abstract：:Eight cases of ventricular parasystole are reported. In all these cases, regardless of whether parasystole seems intermittent or "continuous," the presence of second degree entrance block of the Mobitz type I was suggested. Parasystole alternated with concealed extrasystolic bigeminy showing occasional reentrant extra...

journal_title：Circulation

authors： Kinoshita S

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) are a promising source of cells for regenerating myocardium. However, several issues, especially the large-scale preparation of hiPS-CMs and elimination of undifferentiated iPS cells, must be resolved before hiPS cells can be used clinical...

journal_title：Circulation

authors： Kawamura M,Miyagawa S,Miki K,Saito A,Fukushima S,Higuchi T,Kawamura T,Kuratani T,Daimon T,Shimizu T,Okano T,Sawa Y

更新日期：2012-09-11 00:00:00

abstract：:We have previously shown that a brief episode of ischemia slows the rate of ATP depletion during subsequent ischemic episodes. Additionally, intermittent reperfusion may be beneficial to the myocardium by washing out catabolites that have accumulated during ischemia. Thus, we proposed that multiple brief ischemic epis...

journal_title：Circulation

authors： Murry CE,Jennings RB,Reimer KA

更新日期：1986-11-01 00:00:00

abstract：:In patients treated with sulfinpyrazone, an apparent reduction in the incidence of sudden death and presumed ventricular fibrillation has been reported. Using an intact animal model without microcirculatory thrombosis, we studied the effects of sulfinpyrazone on ischemic myocardium in 58 anesthetized dogs divided into...

journal_title：Circulation

authors： Moschos CB,Escobinas AJ,Jorgensen OB Jr,Regan TJ

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Epidemiological findings suggest an association between low-for-age birth weight and the risk to develop coronary heart diseases in adulthood. During pregnancy, an imbalance between fetal demands and supply may result in permanent alterations of neuroendocrine development in the fetus. We evaluated whether c...

journal_title：Circulation

authors： Ruijtenbeek K,le Noble FA,Janssen GM,Kessels CG,Fazzi GE,Blanco CE,De Mey JG

更新日期：2000-12-05 00:00:00

abstract：BACKGROUND:The study was designed to verify the concept of plaques "at risk" and whether inflammation could play a role in plaque rupture and thrombosis. METHODS AND RESULTS:In 20 patients who had died of acute myocardial infarction, the thrombosed coronary artery was identified and the site of plaque rupture was trac...

journal_title：Circulation

authors： van der Wal AC,Becker AE,van der Loos CM,Das PK

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Lymphatic network and chemokine-mediated signals are essential for leukocyte traffic during the proximal steps of alloimmune response. We aimed to determine the role of lymphatic vessels and their principal growth signaling pathway, vascular endothelial growth factor (VEGF)-C/D/VEGFR-3, during acute and chro...

journal_title：Circulation

authors： Nykänen AI,Sandelin H,Krebs R,Keränen MA,Tuuminen R,Kärpänen T,Wu Y,Pytowski B,Koskinen PK,Ylä-Herttuala S,Alitalo K,Lemström KB

更新日期：2010-03-30 00:00:00

abstract：BACKGROUND:We explored the feasibility of measuring regional tracer activity concentrations and flow defects in myocardium of rats with a high spatial resolution small-animal PET system (microPET). METHODS AND RESULTS:Myocardial images were obtained after intravenous (18)F-fluorodeoxyglucose (18FDG) in 11 normal rats ...

journal_title：Circulation

authors： Kudo T,Fukuchi K,Annala AJ,Chatziioannou AF,Allada V,Dahlbom M,Tai YC,Inubushi M,Huang SC,Cherry SR,Phelps ME,Schelbert HR

更新日期：2002-07-02 00:00:00

abstract：:A technique is described to control recurrent or sustained supraventricular tachycardia associated with rapid ventricular rates following open heart surgery. The technique utilizes a pair of temporarily implanted atrial epicardial wire electrodes to pace the heart. In one group of patients with recurrent atrial flutte...

journal_title：Circulation

authors： Waldo AL,MacLean WA,Karp RB,Kouchoukos NT,James TN

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Differences in vascular reactivity to phenylephrine (PE) responsiveness have been largely evidenced in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Because nitric oxide (NO) strongly affects modulation of the vascular tone in response to vasopressor agents, we hypothesized that the ...

journal_title：Circulation

authors： Philip I,Plantefeve G,Vuillaumier-Barrot S,Vicaut E,LeMarie C,Henrion D,Poirier O,Levy BI,Desmonts JM,Durand G,Benessiano J

更新日期：1999-06-22 00:00:00

abstract：BACKGROUND:The use of atherosclerotic cardiovascular disease (ASCVD) risk to personalize systolic blood pressure (SBP) treatment goals is a topic of increasing interest. Therefore, we studied whether coronary artery calcium (CAC) can further guide the allocation of anti-hypertensive treatment intensity. METHODS:We inc...

journal_title：Circulation

authors： McEvoy JW,Martin SS,Dardari ZA,Miedema MD,Sandfort V,Yeboah J,Budoff MJ,Goff DC Jr,Psaty BM,Post WS,Nasir K,Blumenthal RS,Blaha MJ

更新日期：2017-01-10 00:00:00

abstract：:This study was undertaken to provide a better anatomic description of the location and course of the left coronary artery within a commonly used ultrasonic tomographic plane. Twenty-three hearts were excised at autopsy and scanned in vitro. The locations of the left main (LMCA), left anterior descending (LAD), and lef...

journal_title：Circulation

authors： Rogers EW,Feigenbaum H,Weyman AE,Godley RW,Vakili ST

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Direct thrombin inhibitors are a new class of drugs that may offer a more effective and potentially simpler alternative to heparin. Hirulog is a synthetic peptide based on the leech-derived compound hirudin and, like hirudin, is a highly specific, direct inhibitor of free and clot-bound thrombin. METHODS AN...

journal_title：Circulation

authors： Fuchs J,Cannon CP

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Patients with atrial fibrillation (AF) often take multiple medications. METHODS AND RESULTS:We examined characteristics and compared adjusted outcomes between rivaroxaban and warfarin according to number of concomitant baseline medications and the presence of combined cytochrome P450 3A4 and P-glycoprotein ...

journal_title：Circulation

authors： Piccini JP,Hellkamp AS,Washam JB,Becker RC,Breithardt G,Berkowitz SD,Halperin JL,Hankey GJ,Hacke W,Mahaffey KW,Nessel CC,Singer DE,Fox KA,Patel MR

更新日期：2016-01-26 00:00:00