Cardiac autonomic patterns preceding occasional vasovagal reactions in healthy humans.

abstract：:Eight cases of ventricular parasystole are reported. In all these cases, regardless of whether parasystole seems intermittent or "continuous," the presence of second degree entrance block of the Mobitz type I was suggested. Parasystole alternated with concealed extrasystolic bigeminy showing occasional reentrant extra...

journal_title：Circulation

authors： Kinoshita S

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) and interleukin (IL)-6 are important risk factors for atherosclerosis and coronary heart disease. In the present study, we examined serum levels of CRP and IL-6, IL-6 production by monocytes, and the effect of nasal continuous positive airway pressure (nCPAP) in patients with obstruc...

journal_title：Circulation

authors： Yokoe T,Minoguchi K,Matsuo H,Oda N,Minoguchi H,Yoshino G,Hirano T,Adachi M

更新日期：2003-03-04 00:00:00

abstract：BACKGROUND:In patients with heart failure, excessive sympathetic activation during exercise could interfere with exercise performance by impairing arteriolar dilation in working muscle and by adversely altering skeletal muscle metabolic behavior. To test this hypothesis, we examined the effect of sympathoinhibition wit...

journal_title：Circulation

authors： Lang CC,Rayos GH,Chomsky DB,Wood AJ,Wilson JR

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Adolescent metabolic syndrome (MetS) predicts type 2 diabetes mellitus and subclinical atherosclerosis in adulthood. Our aim was to establish the relationship between an infancy-onset dietary intervention and risk of having MetS between 15 and 20 years of age. METHODS AND RESULTS:The Special Turku Coronary ...

journal_title：Circulation

authors： Nupponen M,Pahkala K,Juonala M,Magnussen CG,Niinikoski H,Rönnemaa T,Viikari JS,Saarinen M,Lagström H,Jula A,Simell O,Raitakari OT

更新日期：2015-02-17 00:00:00

abstract：BACKGROUND:We sought to separately examine the effects of either weight loss or diets varying in protein content and glycemic index without further changes in body weight on cardiovascular risk factors within the Diet, Obesity, and Genes study (DiOGenes). METHODS AND RESULTS:DiOGenes is a pan-European controlled dieta...

journal_title：Circulation

authors： Gögebakan O,Kohl A,Osterhoff MA,van Baak MA,Jebb SA,Papadaki A,Martinez JA,Handjieva-Darlenska T,Hlavaty P,Weickert MO,Holst C,Saris WH,Astrup A,Pfeiffer AF,DiOGenes.

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Morbidity and mortality after conventional repair of thoracoabdominal aneurysms remain high. Alternative techniques have been proposed and are the subject of this report. METHODS AND RESULTS:Endovascular grafts that have a means of incorporating the visceral vessels into the aortic repair were divided into ...

journal_title：Circulation

authors： Greenberg RK,Lytle B

更新日期：2008-04-29 00:00:00

abstract：BACKGROUND:Tenascin is a large extracellular matrix glycoprotein generally found in adult tissues undergoing active remodeling such as healing wounds and tumors. To determine the potential role of tenascin-C (TN-C) in the pathophysiology of atherosclerosis, we investigated the pattern of expression of TN-C in human cor...

journal_title：Circulation

authors： Wallner K,Li C,Shah PK,Fishbein MC,Forrester JS,Kaul S,Sharifi BG

更新日期：1999-03-16 00:00:00

abstract：BACKGROUND:We have previously suggested that the primary arterial switch operation is a feasible strategy for patients with transposition of the great arteries and intact ventricular septum (TGA-IVS) up to age 2 months. This study reports our current results with this approach and examines whether this policy could be ...

journal_title：Circulation

authors： Kang N,de Leval MR,Elliott M,Tsang V,Kocyildirim E,Sehic I,Foran J,Sullivan I

更新日期：2004-09-14 00:00:00

abstract：BACKGROUND:The regulation of the cardiac neutral endopeptidase (EC 24.10, NEP) that degrades bradykinin and natriuretic peptides has been investigated in human cardiac hypertrophy and heart failure. Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies f...

journal_title：Circulation

authors： Fielitz J,Dendorfer A,Pregla R,Ehler E,Zurbrügg HR,Bartunek J,Hetzer R,Regitz-Zagrosek V

更新日期：2002-01-22 00:00:00

abstract：:To determine the evolution of amyloid heart disease, 28 patients with familial amyloid polyneuropathy (FAP) were studied by echocardiography. The incidence and degree of the abnormalities were correlated with the neurologic disabilities, duration of the illness, and age in cross-sectional studies. Serial studies were ...

journal_title：Circulation

authors： Hongo M,Ikeda S

更新日期：1986-02-01 00:00:00

abstract：:It is generally agreed that the conditions leading to myocardial ischemia occur when the oxygen demands of the myocardium exceed the oxygen supply. The major limitations of oxygen supply to the myocardium are atherogenic disease and vasospasm of the coronary arteries. The major hemodynamic determinants of myocardial o...

journal_title：Circulation

authors： Frishman WH

更新日期：1983-06-01 00:00:00

abstract：:A 28-year-old female undergoing elective total hip replacement experienced an anaphylactic reaction to succinylcholine. Hemodynamics, plasma histamine and catecholamines were measured. The tachycardia experienced during the reaction appeared to be secondary to the sympathoadrenal response rather than a direct chronotr...

journal_title：Circulation

authors： Moss J,Fahmy NR,Sunder N,Beaven MA

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Iron overload has an increasing worldwide prevalence and is associated with significant cardiovascular morbidity and mortality. Elevated iron levels in the myocardium lead to impaired systolic and diastolic function and elevated oxidative stress. Taurine accounts for 25% to 50% of the amino acid pool in myoc...

journal_title：Circulation

authors： Oudit GY,Trivieri MG,Khaper N,Husain T,Wilson GJ,Liu P,Sole MJ,Backx PH

更新日期：2004-04-20 00:00:00

abstract：BACKGROUND:The purpose of this investigation was to establish normal values of RR variability for middle-aged persons and compare them with values found in patients early and late after myocardial infarction. We hypothesized that presence or absence of coronary heart disease, age, and sex (in this order of importance) ...

journal_title：Circulation

authors： Bigger JT Jr,Fleiss JL,Steinman RC,Rolnitzky LM,Schneider WJ,Stein PK

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:A family history of coronary heart disease (CHD) is an independent risk factor for cardiovascular events. However, the mechanisms underlying this susceptibility have not been fully elucidated. We hypothesized that an important mediator of the familial predisposition to CHD is subclinical atherosclerosis, whi...

journal_title：Circulation

authors： Wang TJ,Nam BH,D'Agostino RB,Wolf PA,Lloyd-Jones DM,MacRae CA,Wilson PW,Polak JF,O'Donnell CJ

更新日期：2003-08-05 00:00:00

abstract：:Serial electrophysiologic testing of multiple drugs was performed in 21 patients with recurrent atrioventricular (AV) nodal reentrant paroxysmal supraventricular tachycardia (PSVT). All patients had reproducible sustained PSVT induced before drug administration. Serial daily PSVT induction was attempted after administ...

journal_title：Circulation

authors： Bauernfeind RA,Wyndham CR,Dhingra RC,Swiryn SP,Palileo E,Strasberg B,Rosen KM

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:During ischemia, the intracellular calcium and inorganic phosphate (P(i)) concentrations rise and pH falls. We investigated the effects of these changes on force development in donor and failing human hearts to determine if altered contractile protein composition during heart failure changes the myocardial r...

journal_title：Circulation

authors： van Der Velden J,Klein LJ,Zaremba R,Boontje NM,Huybregts MA,Stooker W,Eijsman L,de Jong JW,Visser CA,Visser FC,Stienen GJ

更新日期：2001-09-04 00:00:00

abstract：:The present study was performed to determine whether positron emission tomography (PET) performed after i.v. 11C-palmitate permits detection and characterization of nontransmural myocardial infarction. PET was performed after the i.v. injection of 11C-palmitate in 10 normal subjects, 24 patients with initial nontransm...

journal_title：Circulation

authors： Geltman EM,Biello D,Welch MJ,Ter-Pogossian MM,Roberts R,Sobel BE

更新日期：1982-04-01 00:00:00

abstract：:Expansion (regional dilatation and thinning) of acutely infarcted myocardium in man has been shown to correlate with overall cardiac dilatation and rupture. We studied gross and histopathologic features and the time course of expansion in rats. Infarcts were produced in 84 rats by ligation of the left coronary artery ...

journal_title：Circulation

authors： Hochman JS,Bulkley BH

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Arterial grafts for CABG have been used increasingly, and the radial artery (RA) has become a preferable graft, secondary to the internal mammary artery (IMA). In the present study, we investigated and compared NO release and endothelium-derived hyperpolarizing factor (EDHF)-mediated hyperpolarization for IM...

journal_title：Circulation

authors： He GW,Liu ZG

更新日期：2001-09-18 00:00:00

abstract：:Valve-related complications after Björk-Shiley mitral valve implantation (n = 475), aortic valve implantation (n = 424), or mitral-aortic valve implantation (n = 119) were compared with those after St. Jude Medical mitral valve replacement (n = 173), aortic valve replacement (n = 152), or mitral-aortic valve replaceme...

journal_title：Circulation

authors： Horstkotte D,Körfer R,Seipel L,Bircks W,Loogen F

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Little information is available regarding the occurrence of perioperative and late cardiac events in women with vascular disease. The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value o...

journal_title：Circulation

authors： Hendel RC,Chen MH,L'Italien GJ,Newell JB,Paul SD,Eagle KA,Leppo JA

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:Impaired endothelium-dependent vasodilation is an early sign of atherosclerosis in hypercholesterolemic patients. We hypothesized that lipid-lowering therapy can improve endothelial function and that this effect is mainly mediated by increased bioavailability of nitric oxide (NO). METHODS AND RESULTS:In a r...

journal_title：Circulation

authors： John S,Schlaich M,Langenfeld M,Weihprecht H,Schmitz G,Weidinger G,Schmieder RE

更新日期：1998-07-21 00:00:00

abstract：BACKGROUND:Biological pacemakers (BPM) implanted in canine left bundle branch function competitively with electronic pacemakers (EPM). We hypothesized that BPM engineered with the use of mE324A mutant murine HCN2 (mHCN2) genes would improve function over mHCN2 and that BPM/EPM tandems confer advantage over either appro...

journal_title：Circulation

authors： Bucchi A,Plotnikov AN,Shlapakova I,Danilo P Jr,Kryukova Y,Qu J,Lu Z,Liu H,Pan Z,Potapova I,KenKnight B,Girouard S,Cohen IS,Brink PR,Robinson RB,Rosen MR

更新日期：2006-09-05 00:00:00

abstract：BACKGROUND:The aim of this study was to compare the risk conferred by white-coat versus sustained mild hypertension for the development of cardiovascular disease. METHODS AND RESULTS:Patients (n=479) who underwent 24-hour intra-arterial ambulatory blood pressure monitoring on the basis of a persistently elevated clini...

journal_title：Circulation

authors： Khattar RS,Senior R,Lahiri A

更新日期：1998-11-03 00:00:00

abstract：:Recent molecular studies have suggested that viral myocarditis frequently underlies human congestive cardiomyopathy; however, only moderately sensitive and specific techniques were used. Polymerase chain reaction (PCR) gene amplification is a sensitive, specific technique ideally suited for the diagnosis of viral dise...

journal_title：Circulation

authors： Jin O,Sole MJ,Butany JW,Chia WK,McLaughlin PR,Liu P,Liew CC

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Single-site ventricular pacing in patients with heart failure, atrial fibrillation, and severe atrioventricular (AV) nodal block risks the generation of discoordinate contraction. Whether altering the site of stimulation can offset this detrimental effect and what role sequential right ventricular-left ventr...

journal_title：Circulation

authors： Hay I,Melenovsky V,Fetics BJ,Judge DP,Kramer A,Spinelli J,Reister C,Kass DA,Berger RD

更新日期：2004-11-30 00:00:00

abstract：BACKGROUND:Hypercholesterolemic mice lacking factors required for activation of CD4+ T cells are characterized by reduced development of atherosclerosis. Consequently, it has been assumed that atherosclerosis involves loss of tolerance against modified self-antigens generated in response to hypercholesterolemia and tha...

journal_title：Circulation

authors： Wigren M,Rattik S,Yao Mattisson I,Tomas L,Grönberg C,Söderberg I,Alm R,Sundius L,Ljungcrantz I,Björkbacka H,Fredrikson GN,Nilsson J

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:The use of molecular biological techniques has demonstrated the importance of enteroviral infection of the myocardium in the pathogenesis of myocarditis and dilated cardiomyopathy in adults and adenovirus and enterovirus infection in children. The aim of this study was to determine the frequency of adenovira...

journal_title：Circulation

authors： Pauschinger M,Bowles NE,Fuentes-Garcia FJ,Pham V,Kühl U,Schwimmbeck PL,Schultheiss HP,Towbin JA

更新日期：1999-03-16 00:00:00

abstract：BACKGROUND:Higher carotid intimal-medial thickness (IMT) is associated with cardiovascular risk factors and is predictive of coronary artery disease and stroke in older adults. Carotid IMT was measured in young and middle-aged adults to determine its relationship with risk factors measured (1) in childhood, (2) current...

journal_title：Circulation

authors： Davis PH,Dawson JD,Riley WA,Lauer RM

更新日期：2001-12-04 00:00:00