[Diagnostic validity of attention deficit/hyperactivity disorder: from phenomenology to neurobiology (II)].

Abstract:

:The diagnostic criteria for the attention deficit/hyperactivity disorder (ADHD) were defined by the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders, fourth version. ADHD is a neuro-psychiatric disorder associated with impairments in everyday life and behavioral dysregulation (i.e. inattention, hyper-activity and impulsivity), and it has showed empirical evidence from clinical, pharmacological, and psychometric studies. Nevertheless, the role of neurobiological impairments in the presentation of the symptoms remains unclear. For this paper, the authors reviewed Spanish and English literature that support the neurobiological validity of the disorder, aimed to present evidence associated with its cognitive and behavioral phenotype (e.g. in: neuropsychology, electrophysiology, structural and functional magnetic resonance imaging, neurochemistry and genetics). Additionally, an integrative theoretical clinical and scientific proposal is presented. Finally, the introduction of neurobiological marker as part of the definitive diagnosis is suggested, as a started point for the identification of therapeutic targets.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Trujillo-Orrego N,Ibáñez A,Pineda DA

subject

Has Abstract

pub_date

2012-03-16 00:00:00

pages

367-79

issue

6

eissn

0210-0010

issn

1576-6578

pii

rn2011145

journal_volume

54

pub_type

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