Abstract：
INTRODUCTION:Thymectomy is a surgical procedure which is generally accepted for treatment of myasthenia gravis. OBJECTIVE:To describe the long-term evolution of 217 myasthenic patients who had had thymectomies in the Hospital Clinico Quirurgico Hermanos Ameijeiras in La Habana, Cuba. PATIENTS AND METHODS:We determined the stage of evolution of 217 patients, followed-up periodically, with an average observation time of 83.4 months and an interval of between 5 and 155 months. We also studied the frequency of remission and the influence of a group of variables on this, as well as the mortality and its causes. RESULTS:The clinical state of the patients was: remission 77 (35.4%); pharmacological remission 45 (20.7%); significant improvement 70 (32.2%); the same or worse 5 (2.3%); deaths 11 (5%), and unknown 9 (4.1%). The cases with thymomas had a more unsatisfactory course than the other patients, with fewer remissions and greater mortality. Over the first five years of the evolution of the disease, there was a 30% rate of remission; after five years this rose to 35-40% and after ten years reached 47%. The age of the patient, duration of symptoms, histology of the thymus, age of onset of the disease and duration of follow-up did not have any significant effect (p < 0.05) on the long-term evolution of the thymectomy, in contrast to the gravity of the condition according to Osserman's scale. CONCLUSION:The results of thymectomy, in our study were good and similar to the results reported in the international literature.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Pérez-Nellar J,Negrín A,Llorens JA,Ferrá A,Pardo A,Parisi Nsubject
Has Abstractpub_date
2000-05-01 00:00:00pages
801-6issue
9eissn
0210-0010issn
1576-6578journal_volume
30pub_type
杂志文章abstract：INTRODUCTION:Infantil progressive polydystrophy was described by Alpers in a child with psychomotor retardation, crises which were resistant to treatment and diffuse loss of cortical neurons. OBJECTIVE:The aim of this study was to review the neurophysiological aspects of Alpers syndrome and their clinical correlation....
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
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pub_type： 历史文章,杂志文章,评审
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abstract：INTRODUCTION:Meningitis due to Salmonella is an unusual sign of salmonellosis. Usually Salmonella causes clinical disorders of the digestive tract, but on occasions, especially in babies, may cause focalized infections such as meningitis. Although meningitis due to Salmonella is unusual, it should be remembered because...
journal_title：Revista de neurologia
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更新日期：1998-12-01 00:00:00
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journal_title：Revista de neurologia
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更新日期：2001-05-16 00:00:00
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更新日期：2000-03-16 00:00:00
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更新日期：2002-06-01 00:00:00
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更新日期：2013-09-06 00:00:00
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journal_title：Revista de neurologia
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更新日期：1997-09-01 00:00:00
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更新日期：2003-10-01 00:00:00
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pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
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pub_type： 评论,信件
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更新日期：2012-01-01 00:00:00
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journal_title：Revista de neurologia
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2017-11-01 00:00:00
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doi：
更新日期：2004-10-16 00:00:00
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更新日期：2008-10-01 00:00:00
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doi：
更新日期：2002-02-01 00:00:00
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doi：
更新日期：2010-06-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
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journal_title：Revista de neurologia
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doi：
更新日期：1995-07-01 00:00:00
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更新日期：1998-10-01 00:00:00
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更新日期：2013-10-16 00:00:00
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更新日期：2003-07-01 00:00:00
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pub_type： 杂志文章
doi：10.33588/rn.7002.2019213
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pub_type： 杂志文章,评审
doi：
更新日期：1998-02-01 00:00:00
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doi：
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