Abstract:
OBJECTIVES:The aim of the study was the short term test-retest-reliability of electrophyisiological correlates of simple processes of the motor control, i.e. the execution (go) and the inhibition (no go) of a prepared motor response, evoked during the Continuous Performance Test (CPT). Our interest was centered in the reliability of the topographical P300-parameters described in previous studies, i.e. the localizations of the go and no go centroids and the no go anteriorization (NGA), which is the difference between the two centroid locations. A sufficient reliability is a basic requirement for the application of these new topographical parameters for the investigation of different psychiatric illnesses with suspected dysfunctions of prefrontal motor control, e.g. schizophrenias and affective illnesses, obsessive-compulsive disorders, personality disorders with deficits in impulse control, and in children with attention deficit hyperactivity disorder. PATIENTS AND METHODS:We examined 23 healthy subjects who executed two versions of the CPT with an interval of 30 minutes. After averaging the obtained evoked potentials of each subject, we determined the latencies, amplitudes and positive centroids, at the moment of the peak of the Global Field Power in a P300 time window. RESULTS:Statistical analysis revealed sufficient test-retest-reliabilities in comparison to other electrophysiological paradigms, mainly for the localizations of the go (r = 0.93; p = 10(-10)) and no go centroid (r = 0.85; p = 10(-4)), as well as for the no go anteriorization (r = 0.63; p = 10(-3)). CONCLUSION:These results are a prerequisite for the application of these topographical parameters as measures of the prefrontal motor control in different healthy and psychiatric populations.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Aranda D,Bartsch AJ,Herrmann MJ,Eisenack S,Morínigo JC,Fallgatter AJsubject
Has Abstractpub_date
2001-01-01 00:00:00pages
10-4issue
1eissn
0210-0010issn
1576-6578journal_volume
32pub_type
杂志文章abstract:INTRODUCTION:Cavernous angiomas are angiographically occult vascular malformations that are present in 0.4% of people, and represent 5 13% of all cerebrovascular malformations. They can be alone or multiple, and sporadic or familial. The presence of multiple lesions is more frequent in familial cavernomatosis. OBJECTI...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:Previous epidemiologic studies have shown that around 5% of the population will suffer a tonic clonic seizure during their life. The aim of this study is to know how many and which of these people will suffer a second seizure and become epileptic. PATIENTS AND METHODS:175 patients seen in the emergency depar...
journal_title:Revista de neurologia
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更新日期:2002-05-16 00:00:00
abstract:INTRODUCTION:Congenital malformations of the brain often are complex disorders which display a wide spectrum of neurological manifestations. The presence of this diversity makes it difficult to correlate clinical findings with neuropathological abnormalities or through neuroimaging studies. DEVELOPMENT:Furthermore, th...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:1999-01-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Perinatal asphyxia (PA) and its neurologic manifestations are the most important cause of brain injury and neurologic sequelae in full-term infants. The objective of this study is to analyze the perinatal risk factors of neurologic sequelae in asphyctic term newborns. PATIENTS AND METHODS:One hundred and ...
journal_title:Revista de neurologia
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更新日期:2001-02-01 00:00:00
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journal_title:Revista de neurologia
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journal_title:Revista de neurologia
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journal_title:Revista de neurologia
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更新日期:2017-04-01 00:00:00
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journal_title:Revista de neurologia
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更新日期:2005-09-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2006-04-10 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2001-01-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2002-04-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2017-11-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.6808.2018497
更新日期:2019-04-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-07-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-07-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
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更新日期:2014-02-24 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
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journal_title:Revista de neurologia
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doi:
更新日期:1997-01-01 00:00:00
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journal_title:Revista de neurologia
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doi:
更新日期:2004-06-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2001-06-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-01-15 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.6806.2018242
更新日期:2019-03-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-09-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2020-08-01 00:00:00
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journal_title:Revista de neurologia
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更新日期:2018-02-16 00:00:00
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journal_title:Revista de neurologia
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更新日期:2001-09-01 00:00:00