Abstract：
:Optical coherence tomography (OCT) is a non-invasive imaging technique that allows the different layers of the retina to be visualised in vivo. One of them is the so-called retinal nervous fibre layer (RNFL), which is made up of amyelinic axons from the ganglionic cells, and therefore part of the central nervous system. Recent studies have begun to examine possible applications of OCT in the field of neurology and, more specifically, the usefulness of measuring the thickness of the RNFL in multiple sclerosis (MS). In both cross-sectional and longitudinal studies it has been shown that a decrease in the RNFL is produced in eyes that are affected and unaffected by optic neuritis in MS patients, compared with controls. Several studies have found evidence of an inverse relation between the thickness of the nerve fibre layer and the neurological disability or cerebral atrophy parameters in magnetic resonance imaging of the brain in these same patients. The correlations are, however, weak and sometimes contradictory. Although there are still many doubts that need settling, the role OCT may play in gaining a better understanding of the disease and its follow-up and monitoring seems promising. A review of the different studies published on the thickness of the RNFL in patients with MS will also be conducted.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Vidal-Jordana Á,Sastre-Garriga J,Montalban Xsubject
Has Abstractpub_date
2012-05-01 00:00:00pages
556-63issue
9eissn
0210-0010issn
1576-6578pii
rn2011694journal_volume
54pub_type
杂志文章,评审abstract：:The cognitive effects of the most commonly used antiepileptic drugs (AEDs) are reviewed, discussing both the absolute effects (the effects compared to no treatment) and the relative effects (the comparison of one AED with an other). The cognitive profile per AED is given, based on a literature database, consisting of ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
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更新日期：2002-05-01 00:00:00
abstract：INTRODUCTION:The implementation of an on-call neurology service at our hospital prompted us to analyse the health care it offers. PATIENTS AND METHODS:We conducted a retrospective descriptive study by reviewing the status report of the on-call services performed between 15 April 2002 and 14 April 2003. The data collec...
journal_title：Revista de neurologia
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更新日期：2004-07-16 00:00:00
abstract：:It has been stated that findings in neonatal neurological examinations can play a role as a pointer to adverse developmental outcome. The description of the examinations, and their presence or absence differed among authors without clear reference to their physiological variability ranges. We approached the study of s...
journal_title：Revista de neurologia
pub_type： 杂志文章
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更新日期：2002-03-01 00:00:00
abstract：INTRODUCTION:The research group from Willmes and colleagues is one of the most advanced research groups in cognitive neuroscience. The use and nature of the numeric magnitude representation constitutes one of the study objects of the mentioned research group. This mental representation provokes a great controversy amon...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
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更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinical, electro-encephalographic and evolutionary characteristics of a series of patients diagnosed as having benign neonatal sleep myoclonus (BNSM). MATERIAL AND METHODS:The clinical histories of 21 patients with BNSM were analyzed. Criteria for inclusion in the study were: neonates who ha...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：INTRODUCTION:Pressure is a thermodynamic variable that, like temperature, affects the states of matter. High pressure is an environmental characteristic of the deep sea. Immersion to depth brings about an increase in pressure of 0.1 MPa (1 atm) for each 10 m of seawater. Humans exposed to high pressure, mostly professi...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-11-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
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更新日期：1996-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-08-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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更新日期：2020-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：AIMS:The aim of this study was to determine whether the introduction of generic formulations of antiepileptic drugs (AED) would lead to an economic saving for the public health service. DEVELOPMENT:The narrow therapeutic index, low solubility and non-linear pharmacokinetics of some AED mean that the ranges of bioequiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-03-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-06-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-04-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-07-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-06-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-07-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:Valproic acid (VPA) is an antiepileptic drug widely used in paediatrics. In spite of being a safe and effective anticonvulsant, VPA has been involved in the onset of changes in the metabolism of ammonia and carnitine, although few prospective studies have been made of this. OBJECTIVES:To evaluate the effe...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：INTRODUCTION:The progress made in perinatal health care in recent years has changed the epidemiology of neurological diseases during the neonatal period. The reduction in neonatal mortality has been accompanied by an increasingly large number of patients suffering from disabling diseases or with a risk of suffering fro...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2010-03-16 00:00:00
abstract：:The assessment of memory functions related to medial temporal lobe has become one of the most important issues on current neuropsychology. On this communication, we review the results which our research group has achieved using two functional magnetic resonance Image procedures to assess memory function: Hometown wal...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-02-01 00:00:00
