Abstract:
INTRODUCTION:Statins represent a group of pharmaceutical agents with proven effectiveness and scarce side effects; however, their widespread use increases the probability of the appearance of such adverse effects. DEVELOPMENT:We reviewed the articles that have been published on myotoxicity, neurotoxicity and other cases of disorders affecting the peripheral nervous system, both in reviews and in clinical trials and isolated cases. The frequency of appearance, clinical repercussion, proposed physiopathogenetic mechanisms were analysed in order to draw conclusions regarding the therapeutic attitude that should be adopted. CONCLUSIONS:Generally speaking they are safe pharmaceuticals, but the physician must pay attention to the appearance of possible side effects, given their potential reversibility and lower degree of severity if they are diagnosed at an early stage.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Turpin-Fenoll L,Millan-Pascual J,Martin-Estefania Csubject
Has Abstractpub_date
2008-07-01 00:00:00pages
46-51issue
1eissn
0210-0010issn
1576-6578pii
rn2008230journal_volume
47pub_type
杂志文章,评审abstract:INTRODUCTION:«Man-in-the-barrel» syndrome refers to diplegia of the upper extremities in which mobility of the head and lower limbs is preserved. Brachial plexitis that presents as «man-in-the-barrel» syndrome is an unusual manifestation of giant cell arteritis. We report a case of C5-C6 plexitis as part of the clinica...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract::Neuroinflammation is a key process in the neuropathogenesis of AIDS virus since as a result of the aberrant activation of the chemokine receptors (CXCR4, CX3CR1 and CR5) produces proinflammatory cytokine release by infected cells, increases microglial neurotoxicity and generates lipoperoxides and reactive oxygen speci...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2011-01-16 00:00:00
abstract:INTRODUCTION:The retina is a neuronal membrane that covers the posterior part of the eye chamber and is formed by several layers. The retinal function can be synthesize as the light translation into nervous impulses in the optic nerve. MATERIAL AND METHODS:The ERG is the expression of the changes of the electrical pot...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract:TITLE:Actos reiterativos y ensayo-error. : ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:The exploration of neurocognition in neurology departments has gone a long way from the traditional psychometric tests to the present day use of high technology methods in cognitive neurophysiology, as is the case of event related potentials. Given the increased sensitivity of these procedures, it...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract:INTRODUCTION:There is now growing evidence that essential tremor and Parkinson's disease are related. AIM:To present the main findings from epidemiologic, genetic, clinical, imaging and pathologic studies, contrasting evidences for and against an association between essential tremor and Parkinson's disease. DEVELOPME...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-10-16 00:00:00
abstract:INTRODUCTION:Stroke is a leading cause of mortality and disability. Policosanol has been effective in brain ischemia models. The aim of this study is to investigate whether policosanol, added to aspirin therapy within 30 days of stroke onset, is better than placebo + aspirine for the long-term recovery of non-cardioemb...
journal_title:Revista de neurologia
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2017-02-16 00:00:00
abstract:INTRODUCTION:The spinocerebellar ataxia type 2 has a prevalence of 43 per 100,000 inhabitants in Holguín province, which is the highest one reported worldwide. It is due to an intergenerational CAG repeat expansion contained in the first exon of disease causing gene, and it is characterized by a high variability in its...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-12-16 00:00:00
abstract:AIMS:To evaluate the presence of epileptiform discharges and the organisation of nocturnal sleep of autistic children without nocturnal polysomnographic epileptic seizures. SUBJECTS AND METHODS:Cross section analysis. SUBJECTS:21 boys and girls with autistic spectrum using DSM IV criteria between the ages of 4 and 12...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-06-16 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:The paraneoplastic neurological syndromes are alterations associated with neoplasias. However, they are not caused by metastases or complications such as infections, vascular disorders, metabolic or nutritional alterations or secondary effect of treatment. The paraneoplastic syndromes are o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-12-16 00:00:00
abstract:AIM:To describe the training process of the neuropediatrician in the 21st century in accordance with the clinical and scientific characteristics required by society at a time when there is an explosion of knowledge in neurosciences. DEVELOPMENT:The neuropediatrician of the 21st century, knowing the lack of future prof...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Based on the interrelation between science and philosophy, this article addresses the impact of neurosciences on the philosophical issues posed by today's society, especially those related with epistemology and the philosophy of science. To do so, the different approaches in the cognitive sciences are taken into accou...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2013-03-16 00:00:00
abstract:INTRODUCTION:Restless legs is an unpleasant sensation in the calves that occurs when the individual is sitting or laying down, with an irresistible urge to move the legs. It has been know as a cause of insomnia. We have been using various drugs with a variety of effectiveness. Levodopa is now considered the drug of cho...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-05-16 00:00:00
abstract:INTRODUCTION:The search for variables that mediate in the shift from mild cognitive impairment (MCI) to dementia is currently a very active field of research. In this area, the term cognitive plasticity or modifiability can be of great interest. Proof of the existence of plasticity in the elderly with MCI and its possi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract:INTRODUCTION:Progressive cerebral polidystrophy or Alpers syndrome is a clinico-pathological picture, with no specific biological marker, characterized by involvement mainly of the cerebral grey matter and which shows clinically as a rapidly progressive encephalopathy with intractable seizures, usually myoclonic. The t...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:INTRODUCTION:The cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations of the Notch3 gene in the chromosome 19p13.1. and is characterized by small-vessel disease of the cerebral. The clinical feature consists of migraine, recurrent strokes, mood chan...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-11-16 00:00:00
abstract:INTRODUCTION:Non-communicating hydrocephalus is defined as a blockade of the physiological cerebrospinal fluid (CSF) flow from the choroid plexus to the subarachnoid space. Usually, a ventricle peritoneal shunt with a valve is employed as treatment but this does not provide a physiological restoration on the CSF flow. ...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract:INTRODUCTION:Restless legs syndrome (RLS) is a usual neurologic disorder, often undiagnosed and treatable, usually associated with sleep disturbance. Our goal was to study prevalence of RLS in our practice. PATIENTS AND METHODS:Descriptive, cross-sectional study, in a Primary care center. 283 patients 50 years old or ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:The motor control deficits after stroke affect the gait pattern. There is a significant variability between subjects. AIMS:To analyse, by using a capture motion system, the gait pattern in stroke patients with different levels of motor function, and to establish, despite the participants heterogeneity, wh...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-11-16 00:00:00
abstract:INTRODUCTION:'Sword stroke' linear scleroderma, which is better known as linear scleroderma en coup de sabre (LSCS), is a rare disease with an uncertain causation that is characterised by progressive craniofacial focal atrophy and is, at least in part, different from Parry-Romberg syndrome (PRS). CASE REPORTS:Here, we...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract:INTRODUCTION:We describe a series of 10 children with intracranial hypertension complicating fulminant hepatic failure submitted to intracranial pressure (ICP) monitoring for intensive care and transplantation management. PATIENTS AND METHODS:Information from pediatrics patients acute liver failure admitted to our hos...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION:Congenital hydrocephalus or ventriculomegaly is a disorder that now can be diagnosed in uterus with ultrasonography, this gives the chance of being able to give a treatment the earliest as possible. DEVELOPMENT:The clinical manifestations are reviewed, the diagnosis, the frequent treatment and causes of c...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-10 00:00:00
abstract:INTRODUCTION:Encephalitis due to NMDA receptors antibodies is a relatively common condition but it was under diagnosed until recently. It courses predictably and similarly in adults and children, although there are some differences, still less its association with tumours. CASE REPORT:A 3 years-old girl who was admitt...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-11-16 00:00:00
abstract:INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a neuropathy that affects sensory and motor nerves. The most common CMT subtype is CMT1A due to a PMP22 duplication of a 1.5 Mb fragment on the 17p11.2-p12. The development of a specific molecular technique that detects the PMP22 duplication is necessary for the diagnos...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:The history of prion diseases is one of the most exciting chapters of the story of medicine in the twentieth century. It began in the nineteen twenties when Creutzfeldt (in one patient) and Jakob (in five patients) described a clinically polymorphic cerebral syndrome with a subacute or chro...
journal_title:Revista de neurologia
pub_type: 历史文章,杂志文章
doi:
更新日期:2000-07-16 00:00:00
abstract:INTRODUCTION:Diverse evidences have shown that the process of natural aging causes a decline in different cognitive functions, including among them the attentional process. AIM:To determine how the healthy aging affects to the different attentional networks. SUBJECTS AND METHODS:Two groups: young subjects (32.5 ± 9.7...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Opsoclonus myoclonus is a rare neurological syndrome affecting children and adults, and which is characterised by a sudden onset of chaotic eye movements and myoclonias. In children it generally appears before the age of three as a parainfectious or paraneoplasic process; the type of tumour most frequently...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-08-16 00:00:00
abstract:INTRODUCTION:Alzheimer's disease is 1.5 to 3 times more frequent in women than in men. This fact can be biased as women as a group have more long life survival. Semantic memory and naming are more frequently and severely impaired in women. DEVELOPMENT:Both genetic and environmental factors can contribute when one dete...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2001-06-16 00:00:00
abstract::In this paper we review the relation between epilepsy and the law, more precisely with regard to penal and civil law. Since the new Spanish penal code came into effect in 1996, and especially in view of recent advances in medical knowledge, it is important for doctors and lawyers to make an effort to develop a languag...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-03-16 00:00:00
abstract:AIM:To present seven tumors of the cerebral hemispheres in 6 children with neurofibromatosis type 1 (NF1). PATIENTS AND METHODS:Six patients (three males and three females) of 600 cases of a series with NF1 showed features of cerebral hemispheres tumor (seizures, headache and hemiparesis). They were studied neurologic...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2010-04-16 00:00:00