[Statins and neuromuscular pathology].

Abstract:

INTRODUCTION:Statins represent a group of pharmaceutical agents with proven effectiveness and scarce side effects; however, their widespread use increases the probability of the appearance of such adverse effects. DEVELOPMENT:We reviewed the articles that have been published on myotoxicity, neurotoxicity and other cases of disorders affecting the peripheral nervous system, both in reviews and in clinical trials and isolated cases. The frequency of appearance, clinical repercussion, proposed physiopathogenetic mechanisms were analysed in order to draw conclusions regarding the therapeutic attitude that should be adopted. CONCLUSIONS:Generally speaking they are safe pharmaceuticals, but the physician must pay attention to the appearance of possible side effects, given their potential reversibility and lower degree of severity if they are diagnosed at an early stage.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Turpin-Fenoll L,Millan-Pascual J,Martin-Estefania C

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

46-51

issue

1

eissn

0210-0010

issn

1576-6578

pii

rn2008230

journal_volume

47

pub_type

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