Abstract:
:The relationship between food restriction and subsequent dysregulation of food intake is complex, variable and long-lasting. The present study investigated in rats whether repeated cycles of food restriction and binge feeding opportunities may alter regulation of food intake by employing a test for sensory-specific satiety. Rats that experienced repeated food restriction-binge cycles maintained heavier body weights compared to rats that remained on continuous food restriction. In contrast to the control subjects, rats that alternated between food restriction and binge feeding failed to display sensory-specific satiety. During the first meal, there was a gradual decrease in the amount of food intake over a 40 min period. When presented with a second meal of the same food, these rats responded to the familiar food in a manner similar as to a novel food (i.e., comparable quantities of both types of food were consumed). Food restriction-binge feeding cycles may be considered as a form of stress, which in turn is associated with cross-sensitization to numerous behavioral responses. Therefore, we propose that stress-induced disruption of sensory-specific satiety reflects a sensitized response to food, in which the interaction between sensory and satiety factors are no longer the key regulators of food choice and meal cessation. Furthermore, a role for sensory-specific satiety in terminating food intake appeared to decline with the progression of the cycles, thereby contributing to a steady increase in body weight of rats that experienced restriction with bouts of binge feeding opportunities.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Ahn S,Phillips AGdoi
10.1016/j.bbr.2012.02.017subject
Has Abstractpub_date
2012-06-01 00:00:00pages
279-85issue
2eissn
0166-4328issn
1872-7549pii
S0166-4328(12)00115-5journal_volume
231pub_type
杂志文章abstract:BACKGROUND:Iron deficiency anemia (IDA) has been associated with altered cognitive, motor, and social-emotional outcomes in human infants. We recently reported that rats with chronic perinatal IDA, had altered regional brain iron, monoamines, and sensorimotor skill emergence during early development. OBJECTIVE:To exam...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.04.001
更新日期:2006-08-10 00:00:00
abstract::The effects of bilateral radiofrequency lesions in the region of the entorhinal and piriform cortex (ENT/PIR cortex) on pup-retrieving and ultrasound-elicited pup-searching behavior were investigated in ovariectomized estrogen-treated female mice, which were sensitized to pups by co-caring for a litter for 5 days toge...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(05)80044-0
更新日期:1991-01-31 00:00:00
abstract::Spatial navigation is achieved through both egocentric (body-centered) and allocentric (externally-centered) strategies but decline with age, especially allocentric strategies. A better understanding of the neurobiological mechanisms underlying these strategies would allow the development of new treatments to mitigate...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.12.006
更新日期:2017-03-01 00:00:00
abstract::Although exposure to acute stress has been shown to reinstate extinguished responding for a wide variety of drugs, no studies have investigated stress-induced reinstatement in animals with a history of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) self-administration. Thus, rats were trained to press a lever for M...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.07.056
更新日期:2015-11-01 00:00:00
abstract::The temporoparietal junction (TPJ), along with the anterior insula (AI) and the extrastriate body area (EBA), play a major part in embodiment and self-awareness. However, these connections also appear to be frequently engaged in arousal and attentional processing of external events. Considering that these networks may...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112880
更新日期:2021-01-01 00:00:00
abstract::Pavlovian conditioning of drug effects is generally acknowledged to be a critical factor in the development and persistence of drug addiction. In drug conditioning the focus has essentially been on one type of Pavlovian conditioning, namely, delay conditioning in which the CS and drug UCS overlap and are temporally co...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2014.08.053
更新日期:2014-12-15 00:00:00
abstract::Research into object recognition memory has been galvanised by the introduction of spontaneous preference tests for rodents. The standard task, however, contains a number of inherent shortcomings that reduce its power. Particular issues include the problem that individual trials are time consuming, so limiting the tot...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2014.07.049
更新日期:2015-05-15 00:00:00
abstract::Sleep deprivation (SD) has been reported to induce transient cognitive impairment in functional domains commonly affected in dementia, including memory. Indeed, sleep disturbance has been proposed as an early marker for Alzheimer's disease (AD). SD emulates many aging-related modifications, including important memory ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.112066
更新日期:2019-11-05 00:00:00
abstract::It is known that animals decerebrated at the premammillary level are capable of standing and walking without losing balance, in contrast to postmammillary ones which do not exhibit such behavior. The main goals of the present study were, first, to characterize the postural performance in premammillary rabbits, and, se...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.02.011
更新日期:2008-06-26 00:00:00
abstract::An enriched environment has been shown to influence brain plasticity and function by involving the action of brain-derived neurotrophic factor (BDNF). BDNF, which is synthesized as a precursor molecule (proBDNF) that undergoes proteolytic cleavage, plays an important role in synaptic plasticity and contributes to seve...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.02.022
更新日期:2014-05-15 00:00:00
abstract::Orexinergic system is involved in primary rewards; the neural circuit of the ventral tegmental area (VTA), nucleus accumbens (NAc), prefrontal cortex and amygdala represents overlapping elements mediating the rewarding effects of drugs and stressful experiences. The NAc integrates reward-related information from the V...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.08.021
更新日期:2019-01-01 00:00:00
abstract::Recent work has found that behaviorally inhibited (BI) individuals exhibit enhanced eyeblink conditioning in omission and yoked training as well as with schedules of partial reinforcement. We hypothesized that spacing CS-US paired trials over a longer period of time by extending and varying the inter-trial interval (I...
journal_title:Behavioural brain research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bbr.2016.02.007
更新日期:2016-05-01 00:00:00
abstract::Recent investigations report a higher risk of motor symptoms in females with the FMR1 premutation (PM-carriers) than has hitherto been appreciated. Here we examined basic sensorimotor and postural control under different sensory and attentional dual-task demands. Physiological performance and postural sway measures fr...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.07.033
更新日期:2013-09-15 00:00:00
abstract::Both humans and non-humans discount the value of rewards that are delayed or uncertain, and individuals that discount delayed rewards at a relatively high rate are considered impulsive. To investigate the neural mechanisms that mediate delay discounting, the present study examined the effects of excitotoxic lesions of...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.06.024
更新日期:2006-10-16 00:00:00
abstract::The Morris water maze and the object displacement task are two popular tools used to investigate spatial learning and memory. Research has focused mainly on the acquisition of spatial tasks while little attention has been given to the retention phase. We examined the effects of different training procedures on retenti...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00270-x
更新日期:2003-02-17 00:00:00
abstract::Previous studies suggest an interaction between the level of physical activity and diet preference. However, this relationship has not been well characterized for sex differences that may exist. The present study examined the influence of sex on diet preference in male and female Wistar rats that were housed under eit...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.07.018
更新日期:2017-09-15 00:00:00
abstract::We have developed an adaptive training method which considerably reduces the total time required to train cats to threshold in an orientation discrimination task. During training, the animals are given greater exposure in time to the positive stimulus compared to the negative one. Therefore, this method has been coine...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(90)90153-6
更新日期:1990-01-01 00:00:00
abstract::The immediate early genes (IEGs) have been suggested to be implicated in mechanisms of addiction, as well as in learning and memory processes. fosB, which belongs to IEG, has been reported to have pleiotropic impact on response to psychoactive drugs, as well as motivational and stress-related behaviours. In the presen...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.02.040
更新日期:2008-07-19 00:00:00
abstract:PURPOSE:To explore the effect of vagal nerve stimulation (VNS) on spontaneous brain activity in patients with drug-resistant epilepsy (DRE). METHODS:15 patients and eight healthy controls (HC) were enrolled and scanned by resting-state functional MRI to investigate changes in the fractional amplitude of low-frequency ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112709
更新日期:2020-08-17 00:00:00
abstract::The aim of this study was to investigate the effects of Ginkgo biloba extract (GBE) on cognitive functions as well as oxidative stress and brain-derived neurotrophic factor (BDNF) levels in aged female rats. Rats were divided into 4 groups according to age (young vs. aged) and treatment (GBE vs. vehicle). GBE or vehic...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.10.032
更新日期:2015-02-01 00:00:00
abstract::We used microneurography to characterize stimulus-encoding properties of low-threshold mechanoreceptive afferents in human orofacial tissues. Signals were recorded from single afferents in the infraorbital, lingual and inferior alveolar nerves while localized, controlled, mechanical stimuli were delivered to the facia...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/s0166-4328(02)00151-1
更新日期:2002-09-20 00:00:00
abstract::Enhanced anxiety is a salient feature of a number of psychiatric disorders including anxiety disorders, trauma-related disorders and depression. Although aberrant expression of various genes has been detected in patients suffering from persistent high anxiety as well as in high anxiety rodent models, the molecular mec...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.05.036
更新日期:2016-09-15 00:00:00
abstract::The effects of negative energy balance on self-stimulation are a matter of considerable disagreement. This disagreement undoubtedly reflects the inadequacies of the continuous reinforcement self-stimulation procedures used in this type of experimentation. The present experiment uses a new fixed-interval reinforcement ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(82)90048-1
更新日期:1982-06-01 00:00:00
abstract::The MAM-E17 model is one of the most accepted schizophrenia rat models, which follows the neurodevelopmental theory of the disease. While symptoms of MAM-E17 rats were studied extensively, their examinations were usually restricted to adulthood and in a few cases to prepuberty. It is well known, however, that schizoph...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.05.065
更新日期:2017-08-14 00:00:00
abstract::BALB/cJ and C57BL/6J inbred mouse strains have been proposed as useful models of low and high levels of sociability (tendency to seek social interaction), respectively, based primarily on behaviors of ∼30-day-old mice in the Social Approach Test (SAT). In the SAT, approach and sniffing behaviors of a test mouse toward...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.08.051
更新日期:2013-01-15 00:00:00
abstract::Previous research in humans and animals suggests that prior exposure to stress alters responsivity to drugs of abuse, including psychostimulants. Male rats show an augmented striatal dopamine response to methamphetamine following exposure to chronic unpredictable stress (CUS). Compared to males, female rats have been ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.112176
更新日期:2019-12-30 00:00:00
abstract::Depression, a common mood disorder, involves anhedonia and defects in reward circuits and mesolimbic dopamine transmission in the striatum and nucleus accumbens (NAc). Active vitamin-D, (1,25-(OH)2 vitamin-D3), exerts protective and regulatory effects on the brain dopamine system. In this study, key depression-like sy...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.08.020
更新日期:2019-01-01 00:00:00
abstract::The involvement of the motor system in action language comprehension is a hotly debated topic in cognitive neuroscience and psychology. Recent studies suggest that primary motor cortex (M1) response to action language is context-sensitive rather than automatic and necessary. Specifically, semantic polarity (i.e. affir...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.09.019
更新日期:2018-01-15 00:00:00
abstract::Probabilistic learning is a fundamental cognitive ability that extracts and represents regularities of our environment enabling predictive processing during perception and acquisition of perceptual, motor, cognitive, and social skills. Previous studies show competition between neural networks related to executive func...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2020.112733
更新日期:2020-09-01 00:00:00
abstract::Prenatal exposure to polyriboinosinic-polyribocytidylic acid (poly I:C) results in psychotic-like behavior in mature rat offspring as well as enduring modifications of glutamatergic excitatory synaptic transmission. However, little is known about the dynamic behavioral and glutamate N-methyl-D-aspartate (NMDA) recepto...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.111946
更新日期:2019-09-16 00:00:00