Abstract：
:Menstrual bleeding patterns are considered relevant indicators of reproductive health, though few studies have evaluated patterns among regularly menstruating premenopausal women. The authors evaluated self-reported bleeding patterns, incidence of spotting, and associations with reproductive hormones among 201 women in the BioCycle Study (2005-2007) with 2 consecutive cycles. Bleeding patterns were assessed by using daily questionnaires and pictograms. Marginal structural models were used to evaluate associations between endogenous hormone concentrations and subsequent total reported blood loss and bleeding length by weighted linear mixed-effects models and weighted parametric survival analysis models. Women bled for a median of 5 days (standard deviation: 1.5) during menstruation, with heavier bleeding during the first 3 days. Only 4.8% of women experienced midcycle bleeding. Increased levels of follicle-stimulating hormone (β = 0.20, 95% confidence interval: 0.13, 0.27) and progesterone (β = 0.06, 95% confidence interval: 0.03, 0.09) throughout the cycle were associated with heavier menstrual bleeding, and higher follicle-stimulating hormone levels were associated with longer menses. Bleeding duration and volume were reduced after anovulatory compared with ovulatory cycles (geometric mean blood loss: 29.6 vs. 47.2 mL; P = 0.07). Study findings suggest that detailed characterizations of bleeding patterns may provide more insight than previously thought as noninvasive markers for endocrine status in a given cycle.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Dasharathy SS,Mumford SL,Pollack AZ,Perkins NJ,Mattison DR,Wactawski-Wende J,Schisterman EFdoi
10.1093/aje/kwr356subject
Has Abstractpub_date
2012-03-15 00:00:00pages
536-45issue
6eissn
0002-9262issn
1476-6256pii
kwr356journal_volume
175pub_type
杂志文章abstract：:To examine the interrelationships of cigarette smoking, relative weight, and the occurrence of natural menopause, the authors prospectively evaluated the experience of 66,663 female US registered nurses who were premenopausal in 1976. Over a two-year period, 5004 women became post-menopausal. Current smokers were more...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113598
更新日期：1983-06-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1093/aje/kwi295
更新日期：2005-11-01 00:00:00
abstract：:One frequently analyzes a subset of the data collected in a survey when interest focuses on individuals in a certain subpopulation of the sampled population. Although it may seem natural to eliminate from the data set all data from individuals outside the subpopulation before analysis, this procedure may yield incorre...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008847
更新日期：1996-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/152.9.874
更新日期：2000-11-01 00:00:00
abstract：:Because of the high prevalence of prescription drug use and the incomplete understanding of drug effects at the time of licensing, ongoing epidemiologic monitoring is required to provide information for clinical and regulatory decisions. Data produced through the administration of Medicaid programs have been considere...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115198
更新日期：1989-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/153.4.332
更新日期：2001-02-15 00:00:00
abstract：:Experiencing discrimination is associated with poor mental health, but how cumulative experiences of perceived interpersonal discrimination across attributes, domains, and time are associated with mental disorders is still unknown. Using data from the Study of Women's Health Across the Nation (1996-2008), we applied l...
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pub_type： 杂志文章,多中心研究
doi：10.1093/aje/kwx326
更新日期：2018-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116024
更新日期：1991-11-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 历史文章,杂志文章
doi：10.1093/aje/kwr306
更新日期：2011-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1093/aje/153.1.11
更新日期：2001-01-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114269
更新日期：1986-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwp458
更新日期：2010-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115728
更新日期：1990-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009914
更新日期：1999-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114535
更新日期：1987-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu204
更新日期：2014-10-15 00:00:00
abstract：:The patterns of change in blood lipids, diastolic blood pressure, body mass index, smoking and drinking behaviors, and exercise were examined in an ongoing longitudinal study from 1991 to 1995 of 150 middle-aged Melbourne, Australia, women as they passed through menopause. Changes in risk factors over time were examin...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a010246
更新日期：2000-03-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh316
更新日期：2004-12-01 00:00:00
abstract：:The authors have investigated the effects of parental smoking patterns on the pulmonary function of children in East Boston, Massachusetts. A crude inverse dose-response relationship was observed between the level of FEF25--75% predicted of children who never smoked and the number of smoking parents in the household. ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112783
更新日期：1979-07-01 00:00:00
abstract：:Previous cross-sectional and longitudinal studies assessing the association between age and drinking are inconsistent. Evaluating 15,425 Black and White men and women from four communities, this study sought to determine whether there was a consistent relation between age and drinking in cross-sectional and longitudin...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/153.11.1102
更新日期：2001-06-01 00:00:00
abstract：:A five-year intervention study of the effectiveness of the "Know Your Body" program in reducing coronary heart disease risk factors among black students in the District of Columbia, who were in grades 4-6 at baseline, was begun in 1983. Nine schools were stratified on socioeconomic status and randomly assigned to cont...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1989-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-07-08 00:00:00
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更新日期：2004-09-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
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更新日期：2009-11-01 00:00:00
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更新日期：2016-01-15 00:00:00
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pub_type： 杂志文章
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更新日期：1989-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2001-08-15 00:00:00
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pub_type： 杂志文章
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更新日期：2002-03-15 00:00:00
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更新日期：2009-03-15 00:00:00
abstract：:The association between standardized cancer mortality rate ratios from 1969-1978 and dietary practices was examined in an ecologic study of the 24 counties of Sweden by means of several independent data sources. The study supports the hypothesis that a high intake of cereal fiber protects against colorectal cancer (r ...
journal_title：American journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1093/oxfordjournals.aje.a114789
更新日期：1988-01-01 00:00:00
