Immunosuppressive treatment in primary focal segmental glomerulosclerosis.

abstract：:The newly described endothelium-dependent vasoactive substances, nitric oxide and endothelins, have been the subject of intense investigative interest and have been demonstrated to promote a wide array of autocrine and paracrine functions. Recent data highlight their emerging role as potential important mediators of r...

journal_title：Journal of nephrology

authors： Epstein M,Goligorsky MS

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND AIMS:It has been well documented that gene and DNA alterations occur frequently in benign primary parathyroid adenomas as well as in parathyroid glands with secondary hyperplasia. However, it has not been shown whether a correlation exists between somatic DNA aberrations and clinical data. METHODS:We an...

journal_title：Journal of nephrology

authors： Chudek J,Nagy A,Kokot F,Podwinski A,Wiecek A,Ritz E,Kovacs G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Oxidative stress plays a crucial role in chronic complications of diabetes such as diabetic nephropathy (DN), the main cause of renal failure. In diabetes, whether peroxynitrite (ONOO(-)), generated from inducible nitric oxide synthase (iNOS) induced by tumor necrosis factor alpha (TNF-alpha), plays a primar...

journal_title：Journal of nephrology

authors： Xiao H,Li Y,Qi J,Wang H,Liu K

更新日期：2009-11-01 00:00:00

abstract：:On September 11, 1945, Maria Schafstaat was the first patient who successfully underwent a dialysis treatment for acute kidney injury (AKI). The ingenious design of the first dialysis machine, made of cellophane tubing wrapped around a cylinder that rotated in a bath of fluid, together with the brave determination to ...

journal_title：Journal of nephrology

authors： Kielstein JT,Schiffer M,Hafer C

更新日期：2010-09-01 00:00:00

abstract：:John Allen, a British physician of the eighteenth century, deserves being remembered for a series of inventions, but most importantly -- from a 'medical' point of view -- for his highly praised manuscript, the 'Universae Medicinae Practicae,sive Doctissimorum Virorum de Morbis Eorumque Causis ac Remediis Judicia', whi...

journal_title：Journal of nephrology

authors： Mezzogiorno A,Iorio L,Esposito A,Flamourakis M,Esposito V

更新日期：2006-05-01 00:00:00

abstract：:The origin of the Teutonic Order of Hospitalers St. Mary (Ordo Hospitalis S. Mariae Teutonicorum Hi-erosolymitani) is presented. The St. Mary Hospitaler Teutonic Order arrived in the XIIIth century to Pomezania, then inhabited by pagan Prussian tribes. The Knights of the Order started to Christianize the Prussians, th...

journal_title：Journal of nephrology

authors： Zydowo MM

更新日期：2006-05-01 00:00:00

abstract：:Lupus is now regarded as a syndrome which results from several related auto-immune processes, although the exact mechanisms of how the disease arises in susceptible individuals remain obscure. When the San Carlo meetings began in 1968, much less was known about the pathogenesis of autoimmunity, but the presence of aut...

journal_title：Journal of nephrology

authors： Cameron JS

更新日期：1999-07-01 00:00:00

abstract：:Some antihypertensive drugs may have a renoprotective effect, that is partially independent of their ability to reduce blood pressure. ACE-inhibitors are safe and effective agents that are capable of reducing proteinuria and preventing CRF progression. The results of the AIPRI extension study suggest that they may als...

journal_title：Journal of nephrology

authors： Locatelli F,Del Vecchio L,Marai P,Colzani S

更新日期：1998-11-01 00:00:00

abstract：:Modern nephrology developed in Poland mostly from the internal medicine department chaired in Warsaw by the great internist prof. Witold Orłowski (1874-1966). Three of his pupils Tadeusz Orłowski, Jan Roguski and Jakub Penson independently established the foundations of clinical nephrology and renal replacement therap...

journal_title：Journal of nephrology

authors： Czekalski S,Rutkowski B

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peritonitis is the major cause of peritoneal dialysis (PD) technique failure. Prophylactic topical antibiotics have been reported to reduce peritoneal dialysis catheter exit site infections (ESI) and peritonitis rates. METHODS:We audited the effect of different exit site practices in the 12 P...

journal_title：Journal of nephrology

authors： Davenport A,Pan Thames Renal Audit Peritoneal Dialysis Group.

更新日期：2012-09-01 00:00:00

abstract：:Highly concentrated marine polyunsaturated fatty acids (n-3 PUFA), affecting the lipids and lipophilic drugs metabolism, can interfere with cyclosporine (CyA) pharmacokinetics. This prospective, randomized and placebo-controlled, double-blind study involved 42 kidney graft recipients. From day +1, 21 pts (E) received ...

journal_title：Journal of nephrology

authors： Busnach G,Stragliotto E,Minetti E,Perego A,Brando B,Broggi ML,Civati G

更新日期：1998-03-01 00:00:00

abstract：:The Liber medicine orinalibus (codex 69 Montecassino) of Hermogenes is the first known manuscript to have a Latin translation from the original Greek work of Magnus of Emesa (or Nisibis). The particular text here translated, from the so-called Commentatio, mentions direct transliteration of Greek concepts such as chym...

journal_title：Journal of nephrology

authors： Iorio L,Lamagna M

更新日期：2011-05-01 00:00:00

abstract：:During Fabry disease, progressive glycosphingolipid deposition in the kidney causes gradual deterioration of renal function with proteinuria, uremia and hypertension. This results in end-stage renal disease (ESRD) which is one of the leading causes of morbidity and premature mortality in affected patients. Given the e...

journal_title：Journal of nephrology

authors： Cybulla M,Kurschat C,West M,Nicholls K,Torras J,Sunder-Plassmann G,Feriozzi S

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) and chronic kidney disease (CKD) lead to high morbidity and mortality rates. Traditional and nontraditional risk factors, hypertension, fluid overloading and anemia can lead to myocardial ischemia, chamber hypertrophy and dilatation, and low left ventricular ejection fraction (L...

journal_title：Journal of nephrology

authors： Wu IW,Hung MJ,Chen YC,Hsu HJ,Cherng WJ,Chang CJ,Wu MS

更新日期：2010-03-01 00:00:00

abstract：:Cell-to-cell signal exchange during antigen presentation deeply influences the profile and extent of the immune response. Together with the TCR/MHC-mediated signal, accessory signals are provided to the T cell by the antigen-presenting cell (APC), through specific receptor-ligand interactions that represent indispensa...

journal_title：Journal of nephrology

authors： Biancone L,Deambrosis I,Camussi G

更新日期：2002-01-01 00:00:00

abstract：:The pathogenetic role of adiponectin (ADPN) in kidney failure is not yet elucidated, since in vitro and in vivo studies have demonstrated that ADPN exerts both anti-inflammatory and pro-inflammatory effects. Starting from our previous findings demonstrating that HK-2 cells express and secrete ADPN, in this study we in...

journal_title：Journal of nephrology

authors： Perri A,Vizza D,Lupinacci S,Toteda G,De Amicis F,Leone F,Gigliotti P,Lofaro D,La Russa A,Bonofiglio R

更新日期：2016-04-01 00:00:00

abstract：AIMS:To examine the distribution of bone mineral density (BMD) in different histological groups of renal osteodystrophy. PATIENTS:We prospectively studied 62 patients, 41 men and 21 women, aged 57+/-11.5 years, who had been on hemodialysis for 60+/-55 months. The women had been amenorrheic for 13+/-4 years and 7 patie...

journal_title：Journal of nephrology

authors： Gerakis A,Hadjidakis D,Kokkinakis E,Apostolou T,Raptis S,Billis A

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Plasmin has recently been reported to be associated with renal fibrosis in experimental models, but its role in human renal diseases is unclear. METHODS:Fifty-seven patients with IgA nephropathy (IgAN) were evaluated retrospectively. Plasmin in their renal biopsy tissues was assessed by in situ zymography u...

journal_title：Journal of nephrology

authors： Uchida T,Oda T,Takechi H,Matsubara H,Watanabe A,Yamamoto K,Oshima N,Sakurai Y,Kono T,Shimazaki H,Tamai S,Kumagai H

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Lack of adherence may influence the efficiency of phosphate binders. Our clinical hypothesis was that if lanthanum carbonate (LC) might offer some advantage over sevelamer (S), that that would be in those patients in whom serum phosphate (P) levels were not controlled by S or in those requiring high doses ...

journal_title：Journal of nephrology

authors： Arenas MD,Rebollo P,Malek T,Moledous A,Gil MT,Alvarez-Ude F,Morales A,Cotilla E

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:This study investigated whether modifications of placental expression of endothelin-1 (ET-1), nitric oxide synthase (NOS) and tissue factor (TF) are associated with abnormal Doppler waveforms. METHODS:Fourteen pre-term severe preeclamptic (PE) women with fetal growth restriction (FGR) and 14 normal preg nan...

journal_title：Journal of nephrology

authors： Di Paolo S,Volpe P,Grandaliano G,Stallone G,Schena A,Greco P,Resta L,Selvaggi L,Cincione R,Schena FP,Gesualdo L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Rituximab (RTX) is approved for remission induction in ANCA associated vasculitis (AAV). However, data on use of RTX in patients with severe renal disease is lacking. METHODS:We conducted a retrospective multi-center study to evaluate the efficacy and safety of RTX with glucocorticoids (GC) with and without...

journal_title：Journal of nephrology

authors： Geetha D,Hruskova Z,Segelmark M,Hogan J,Morgan MD,Cavero T,Eriksson P,Seo P,Manno RL,Dale J,Harper L,Tesar V,Jayne DR

更新日期：2016-04-01 00:00:00

abstract：:Membranous glomerulopathy (MGN) is a frequent cause for nephrotic syndrome in adults. In this overview, the basic pathogenic features of Heymann nephritis, a "classical" model of MGN in rats, are compared with those of human MGN. While the pathogenic antigen(s) of rat Heymann nephritis (the polyspecific receptor prote...

journal_title：Journal of nephrology

authors： Kerjaschki D

更新日期：2000-11-01 00:00:00

abstract：:The most common cause of liver disease worldwide is now non-alcoholic fatty liver disease (NAFLD). NAFLD refers to a spectrum of disease ranging from steatosis to non-alcoholic steatohepatitis, causing cirrhosis, and ultimately hepatocellular carcinoma. However, the impact of NAFLD is not limited to the liver. NAFLD h...

journal_title：Journal of nephrology

authors： Kanbay M,Bulbul MC,Copur S,Afsar B,Sag AA,Siriopol D,Kuwabara M,Badarau S,Covic A,Ortiz A

更新日期：2020-05-21 00:00:00

abstract：INTRODUCTION:Contrast-induced acute kidney injury, also referred to as contrast-induced nephropathy (CIN), is a potentially serious renal complication associated with the use of iodinated contrast media (CM) in patients at risk. With the dramatic growth in contrast-enhanced imaging services worldwide, including procedu...

journal_title：Journal of nephrology

authors： Reddan D,Laville M,Garovic VD

更新日期：2009-05-01 00:00:00

abstract：:The metabolic syndrome is a cluster of cardiometabolic alterations at least partly dependent on reduced insulin sensitivity and hyperinsulinemia that can have several renal implications. A systematic review and meta-analysis of studies available in the international literature in English language demonstrates that the...

journal_title：Journal of nephrology

authors： Rendina D,De Filippo G,D'Elia L,Strazzullo P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Severe hyperhomocysteinemia is common in hemodialysis patients, who also present a dramatic increase in plasma concentrations of sulfate, one of the main products of methionine and cysteine catabolism. The aim of this study was to verify the relationship between high plasma sulfate levels and cysteine or hom...

journal_title：Journal of nephrology

authors： Brunetti M,Terracina L,Timio M,Saronio P,Capodicasa E

更新日期：2001-01-01 00:00:00

abstract：:Epicardial adipose tissue (EAT) is localized between the myocardial surface and visceral layer of the pericardium. It is a metabolically active organ that secretes several cytokines which modulate cardiovascular morphology and function. EAT may interact locally with coronary arteries through paracrine secretion mechan...

journal_title：Journal of nephrology

authors： Russo R,Di Iorio B,Di Lullo L,Russo D

更新日期：2018-12-01 00:00:00

abstract：:End-stage renal disease (ESRD) is a significant global health problem that places a considerable burden on health care resources. The leading cause of death in ESRD patients is cardiovascular disease, which is often preceded by changes in cardiac geometry, including left ventricular hypertrophy (LVH). Treatments that ...

journal_title：Journal of nephrology

authors： Culleton BF,Asola MR

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Uremic pruritus as a symptom that affects hemodialysis (HD) patients can decrease the quality of life and increase morbidity in these patients. The aim of this study was to evaluate the effects of turmeric on uremic pruritus in HD patients. SUBJECTS AND METHODS:This was a double-blind placebo-controlled tri...

journal_title：Journal of nephrology

authors： Pakfetrat M,Basiri F,Malekmakan L,Roozbeh J

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that bleeding times have positive predictive values of only 5% for perioperative bleeding in unselected populations. Nevertheless, performing bleeding times prior to all renal biopsies is common in nephrology practice. METHODS:We report complications of 112 renal biopsies done at...

journal_title：Journal of nephrology

authors： Stiles KP,Hill C,LeBrun CJ,Reinmuth B,Yuan CM,Abbott KC

更新日期：2001-07-01 00:00:00