Abstract：
:Placentas from karyotypically abnormal fetuses (18 to 23 weeks' gestation) were analyzed prospectively at the light microscopic level. Group I consisted of 14 control placentas. Group II consisted of 14 placentas from fetuses with an abnormal karyotype. Secondary and tertiary stem villi counts, small muscular artery counts, and total vessel counts were determined per 100 x field. There were no differences in secondary and tertiary stem villi counts between groups. A significant decrease in small muscular artery counts (p less than 0.01) and total vessel counts (p less than 0.01) was noted in group II. Placental and fetal weights were comparable between groups. This undervascularization may represent placental immaturity as a result of arrested or delayed angiopoiesis. It appears that this abnormality is established before the third trimester and may be enhanced by late vascular obliteration as reported by others. These data substantiate the concept that the structure and function of the placenta is determined to a great degree by fetal karyotype and may help explain the morbidity and mortality seen in these fetuses.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Kuhlmann RS,Werner AL,Abramowicz J,Warsof SL,Arrington J,Levy DLdoi
10.1016/0002-9378(90)90704-bsubject
Has Abstractpub_date
1990-10-01 00:00:00pages
1264-70issue
4 Pt 1eissn
0002-9378issn
1097-6868pii
0002-9378(90)90704-Bjournal_volume
163pub_type
杂志文章abstract：:The possibility of dispersing viral deoxyribonucleic acid during carbon dioxide laser treatment of human papillomavirus-containing genital infections has been investigated with a commercially available dot blot hybridization technique. The viral ribonucleic acid probes were specific for groups of human papillomavirus ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90705-c
更新日期：1990-10-01 00:00:00
abstract：OBJECTIVE:The objective of this prospective observational study was to determine whether the preanalytical management of maternal plasma glucose samples had a significant effect on glucose measurements in obese pregnant women. STUDY DESIGN:Based on the accurate calculation of body mass index in the first trimester, ob...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2015.03.022
更新日期：2015-07-01 00:00:00
abstract：:The mechanisms responsible for twinning and disorders of twin gestations have been the subject of considerable interest by physicians and scientists, and cases of atypical twinning have called for a reexamination of the fundamental theories invoked to explain twin gestations. This article presents a review of the lite...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2015.10.930
更新日期：2016-02-01 00:00:00
abstract：:In an effort to develop guidelines for the management of acute genital injuries in prepubertal girls, we categorized 32 cases by the object that allegedly caused the injury: straddle injuries, nonpenetrating injuries, penetrating injuries, and torque injuries. Using these categories and the anatomic features of symmet...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91620-p
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:We evaluated four oral combinations of conjugated estrogens (Premarin) and medroxyprogesterone acetate in preventing endometrial hyperplasia, which can occur with conjugated estrogens alone. STUDY DESIGN:This was a 1-year prospective, double-blind, randomized, multicenter study in 1724 postmenopausal women. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0002-9378(94)70129-6
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:We sought to test the hypothesis that elective delivery of infants diagnosed with macrosomia by ultrasonographic studies in diabetic women will significantly reduce the rate of shoulder dystocia without significantly increasing cesarean section rate. STUDY DESIGN:In a prospective study diabetic women with ul...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(98)70524-1
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:Our purpose was to study the effects of isradipine, a dihydropyridine calcium channel blocker, on mother and fetus in the treatment of hypertensive disorders of pregnancy. STUDY DESIGN:The investigation was performed as a two-group, parallel, double-blind multicenter study of isradipine versus placebo. Fifty...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-9378(95)90357-7
更新日期：1995-09-01 00:00:00
abstract：:There were 153 oral prostaglandin (PG) E2 inductions attempted in 149 patients. For various reasons nine cases were dropped from the study. Of the remaining 144 induction attempts, 96 were judged successful, with a success rate of 67 per cent. Details of these inductions are presented, including summaries of three pat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(78)90857-8
更新日期：1978-11-15 00:00:00
abstract：:This study was undertaken to evaluate the catecholamine response of the fetal rat to insulin-induced hypoglycemia in the mother. Twenty-four Sprague-Dawley rats at day 21 of gestation were used. Hypoglycemia was induced with regular insulin; then at timed intervals, the rats were anesthetized with pentobarbital. When ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(81)90317-3
更新日期：1981-02-15 00:00:00
abstract：OBJECTIVE:The purpose of this study was to estimate the frequency at which laparoscopic surgery is performed to treat female pelvic pain. STUDY DESIGN:Using the National Survey of Ambulatory Surgery, we performed a retrospective, cross-sectional study of women who had been diagnosed with abdominal or pelvic pain who u...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2005.09.001
更新日期：2006-03-01 00:00:00
abstract：:Reanalysis of data on the ovulation method of natural family planning collected by the World Health Organization yields the following conclusions. The method is effective during perfect (correct and consistent) use, with a first-year probability of failure of 3.4%. However, it is extremely unforgiving of imperfect use...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)90581-x
更新日期：1991-12-01 00:00:00
abstract：:Fifty-one patients with granulosa-cell tumors and nine patients with Sertoli-Leydig-cell tumors have been treated at the M. D. Anderson Hospital. The most important prognostic finding was the stage of the tumor when first seen. Conservative surgery was utilized in young patients with lesions confined to one ovary. Mor...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90577-9
更新日期：1976-06-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to investigate whether performing an amniocentesis increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 (MTCT). STUDY DESIGN:We studied HIV -1 infected mothers and their children enrolled in the multicenter French Perinatal HIV Cohort from 1985 to 2006...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2008.08.049
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to identify the external funding status of the most frequently cited obstetrical publications (citation classics) and to assess trends in funded vs nonfunded manuscripts as well as each publication's type of external funding. STUDY DESIGN:For the first objective, the citation c...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2013.05.021
更新日期：2013-08-01 00:00:00
abstract：:We describe a patient who had abnormal sonographic findings of the liver 24 hours before signs and symptoms of severe preeclampsia and HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). The abnormal sonographic appearance of the liver prompted further investigation and was instrumental in the ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(85)80047-8
更新日期：1985-07-15 00:00:00
abstract：OBJECTIVE:This study examined the effects of the chemopreventive agents 4-(N-hydroxyphenyl)retinamide (4-HPR) and alpha-difluoromethylornithine (DFMO) on leiomyoma growth. STUDY DESIGN:Primary cultures of human uterine leiomyomas and matched normal myometrium were established from hysterectomy specimens. After treatme...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2003.09.048
更新日期：2004-03-01 00:00:00
abstract：:Platelet-poor plasma from 13 nonpregnant, 33 normally pregnant, and eight preeclamptic women was incubated with prostacyclin. The ability of platelet-poor plasma to diminish the antiaggregatory effect of prostacyclin was assessed by measuring this effect on arachidonic acid-induced platelet aggregation. Platelet aggre...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(87)90370-x
更新日期：1987-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine risk factors for trocar implantation metastasis after diagnostic laparoscopy in patients with primary or recurrent advanced ovarian cancer. STUDY DESIGN:Eighty-three women with primary advanced ovarian cancer and 21 women with recurrent ovarian cancer undergoing a l...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(99)70489-8
更新日期：1999-09-01 00:00:00
abstract：:The influence of caffeine and cigarette consumption on fetal growth during pregnancy was studied retrospectively in 913 newborn infants. Analysis of variance was adjusted for length of gestation and sex. A significant caffeine-cigarette interaction was found on birth weight (F = 85.4, p less than 0.01). Among women sm...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80301-0
更新日期：1987-11-01 00:00:00
abstract：:The prophylactic use of oral terbutaline was studied in 28 normal, healthy, low-risk women with twin gestations. The mean birth weights were significantly increased over those in a similar group of control patients. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(86)90481-3
更新日期：1986-04-01 00:00:00
abstract：:Previous studies in our laboratory have suggested that measurement of methylumbelliferylguanidinobenzoate (MUGB) reactive proteases in midtrimester amniotic fluid is potentially of value for the intrauterine detection of cystic fibrosis. Thirty-nine pregnancies of obligate heterozygotes of cystic fibrosis and 12 cases...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(16)32679-5
更新日期：1981-12-15 00:00:00
abstract：OBJECTIVE:Maternal floor infarction of the placenta is characterized by gross placental abnormalities and histologic evidence of X-cell proliferation. Previously, pregnancy-associated major basic protein has been localized to the placental X cell and identified at elevated levels in serum and amniotic fluid in all norm...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)91716-5
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine how closely the surgically induced sheep myelomeningocele (MMC) model resembles the central nervous system derangements seen in human disease, and identify which aspects of MMC are the result of the early neuronal developmental defect, and which are secondary to the ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2005.02.110
更新日期：2005-10-01 00:00:00
abstract：:To determine if the activity of the adrenocorticotropic hormonal-adrenal axis is modulated in part by estrogens and progestins, we have compared pituitary and adrenal responses to corticotrophin-releasing hormone in normal women during the early follicular, late follicular, and midluteal phases of the menstrual cycle ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80229-6
更新日期：1987-12-01 00:00:00
abstract：:The effect of menstrual cycle phases on the indexes of magnesium and zinc status was assessed in five normally menstruating women. Plasma concentrations of magnesium and zinc and the magnesium and zinc content of red blood cells and peripheral blood mononuclear cells were measured for 3 or 5 days per week during three...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80096-0
更新日期：1987-10-01 00:00:00
abstract：OBJECTIVE:Our purpose was to study the fetal central venous pressure waveform recorded noninvasively from the inferior vena cava in normal and complicated pregnancies by means of newly developed equipment to follow the vessel lumen diameter. STUDY DESIGN:A paired ultrasonic phase-locked loop echo tracking system with ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90083-7
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to test the hypothesis that infusion of the oxytocin antagonist atosiban results in decreased preterm uterine activity in the human. STUDY DESIGN:A randomized, double-blind, placebo-controlled trial was performed. One hundred twenty women from 20 to 36 weeks' gestation with a co...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0002-9378(94)70214-4
更新日期：1994-02-01 00:00:00
abstract：:Seventeen human fetal and neonatal pituitary glands were removed at necropsy, and analyzed for oxytocin content by a specific and sensitive radioimmunoassay, after homogenization in 0.4M acetic acid. Serial dilution of the pituitary extract showed parallelism with the oxytocin standard curve on the radioimmunoassay. C...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(84)90719-1
更新日期：1984-02-15 00:00:00
abstract：OBJECTIVES:The study was undertaken to compare Hispanic birth outcomes with those of white and African American women in North Carolina and to examine variables associated with adverse birth outcomes among Hispanic women. STUDY DESIGN:Retrospective comparison of birth outcomes by ethnicity/race, from linked birth/infa...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.348
更新日期：2003-05-01 00:00:00
abstract：:Phencyclidine, a frequently abused drug, has been shown to cross the placenta and may cause harmful effects in the fetus. Therefore, a prospective study was undertaken to determine the extent of phencyclidine use during pregnancy. Two thousand three hundred twenty-seven pregnant women were screened for phencyclidine u...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(84)80063-0
更新日期：1984-02-01 00:00:00
