Abstract:
:Anaplasma phagocytophilum, the causative agent of human granulocytic anaplasmosis, is an obligate intra-cellular bacterium that survives in neutrophils by delaying apoptosis. The human promyelocytic leukemia cell line HL-60 has been the ultimate choice for culturing Anaplasma in vitro. In this study, we assessed the various events of drug-induced apoptosis in A. phagocytophilum-infected HL-60 cells. Anaplasma infection reduced the cell viability and increased the apoptosis in HL-60 cells and staurosporine or etoposide-induced apoptosis was further exacerbated with Anaplasma infection. Altogether our results suggest that A. phagocytophilum infection is proapoptotic in HL-60 cells unlike in neutrophils where it is antiapoptotic.
journal_name
World J Microbiol Biotechnoljournal_title
World journal of microbiology & biotechnologyauthors
Karki P,Ijdo JWdoi
10.1007/s11274-011-0745-zsubject
Has Abstractpub_date
2011-11-01 00:00:00pages
2741-2746issue
11eissn
0959-3993issn
1573-0972journal_volume
27pub_type
杂志文章abstract::Drotaverine [1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline] hydrochloride, an antispasmodic drug derived from benzylisoquinoline was evaluated for its biodegradability using a bacterial strain Rhodococcus rhodochrous IEGM 608. The experiments were performed under aerobic conditions with rhodo...
journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/BF00383067
更新日期:1993-05-01 00:00:00
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/BF00361025
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/s11274-013-1594-8
更新日期:2014-06-01 00:00:00
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
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更新日期:2014-05-01 00:00:00
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
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abstract::Adhesion ability is a primary criterion for the selection of probiotic microorganisms. Lactic acid bacteria contribute the majority of microorganisms with probiotic properties. They have several important mechanisms for intestinal epithelial cell adhesion. In order to adhere to the intestinal cells, they generally use...
journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章,评审
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journal_title:World journal of microbiology & biotechnology
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/s11274-020-02989-x
更新日期:2021-01-11 00:00:00
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/BF01200938
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/s11274-017-2389-0
更新日期:2017-12-18 00:00:00
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journal_title:World journal of microbiology & biotechnology
pub_type: 杂志文章
doi:10.1007/s11274-005-9028-x
更新日期:2006-03-01 00:00:00
abstract::A strain of Pleurotus ostreatus was grown in tomato pomace as sole carbon source for production of laccase. The culture of P. ostreatus revealed a peak of laccase activity (147 U/L of fermentation broth) on the 4th day of culture with a specific activity of 2.8 U/mg protein. Differential chromatographic behaviour of l...
journal_title:World journal of microbiology & biotechnology
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