Abstract:
BACKGROUND:Health-related quality of life instruments are typically developed and validated for use in developed countries by patients who can read and write. Little is known about the feasibility of using adaptations of validated instruments in situations where literacy rates are low. OBJECTIVE:We aimed to translate, culturally adapt, and test an oral version of Skindex-16 in Runyankore, the predominant language in Mbarara, Uganda, for use in dermatologic research. METHODS:Skindex-16 was forward- and back-translated to Runyankore. The Runyankore version was administered orally to 47 dermatology patients and 47 random hospital visitors. Additional questions regarding duration, dyspigmentation, concealment status of the skin problem, and overall quality of life effect were also asked. RESULTS:Oral delivery was feasible; ≤ 10 minutes per subject. High Cronbach α values (0.86, 0.88, and 0.85 for symptoms, emotions, and functioning subscales, respectively) demonstrated internal consistency reliability. As hypothesized, subjects with reported skin problems, dyspigmentation, and difficulty in concealment had higher mean Skindex scores. A total of 72.4% of responses to the open-ended question were addressed in Skindex-16, indicating content validity. CONCLUSION:The orally delivered Runyankore version of Skindex-16 is reliable, with construct and content validity, and feasible for use in dermatology research in Mbarara, Uganda. Orally administered quality of life instruments have potential for use in low literacy groups worldwide.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Chua SL,Maurer T,Chren MMdoi
10.1111/j.1365-4632.2011.04894.xsubject
Has Abstractpub_date
2011-10-01 00:00:00pages
1249-54issue
10eissn
0011-9059issn
1365-4632journal_volume
50pub_type
杂志文章abstract::Alopecia areata is a T cell mediated disease with which many disorders may be associated. There are few studies reporting ocular findings in alopecia areata. The aim of the study is to assess tear function and ocular surface pathologies in alopecia areata. Thirty-two patients with alopecia areata and 20 age- and sex-m...
journal_title:International journal of dermatology
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abstract:BACKGROUND:Herpes simplex virus (HSV) infections are usually chronically recurrent in the normal population and represent a significant cause of morbidity in immunocompromised patients. Acyclovir (ACV) is widely used for the treatment and prophylaxis of HSV infections. The emergence of ACV-resistant strains has been fr...
journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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abstract:BACKGROUND:In this study, we have investigated the chemotherapeutic potential of a purple violet pigment (PVP), which was isolated from a previously undescribed Antarctic Janthinobacterium sp. (Ant5-2), against murine UV-induced 2237 fibrosarcoma and B16F10 melanoma cells. METHODS:The 2237, B16F10, C50, and NIH3T3 cel...
journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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doi:10.1111/j.1365-4362.1992.tb03947.x
更新日期:1992-05-01 00:00:00
abstract::Currently available treatment options for melasma include prevention of UV radiation, topical lightening agents, chemical peels, and light-based and laser therapies. However, none have shown effective and sustained results, with incomplete clearance and frequent recurrences. There has been increasing interest recently...
journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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abstract:BACKGROUND:CD4+ CD25+ T-regulatory (Treg) cells play critical roles in maintaining peripheral tolerance and preventing autoimmunity. As characteristics of Treg cells have not been precisely investigated in chronic urticaria (CU) yet, this study was performed. OBJECTIVE:To determine the frequencies of circulating CD4+ ...
journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:1994-04-01 00:00:00
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journal_title:International journal of dermatology
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更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:International journal of dermatology
pub_type: 杂志文章
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journal_title:International journal of dermatology
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abstract::Overproduction of sweat, sweaty skin, and body malodors are felt unpleasant by many people in diverse social groups. This review summarizes the functional aspects of the eccrine, apocrine, and apoeccrine sweat glands as encountered in health and disease. A series of measuring methods are conveniently used to explore a...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
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更新日期:2012-06-01 00:00:00