Abstract：
:Episodic memory is a polygenic behavioral trait with substantial heritability estimates. Despite its complexity, recent empirical evidence supports the notion that behavioral genetic studies of episodic memory might successfully identify trait-associated molecules and pathways. The development of high-throughput genotyping methods, of elaborated statistical analyses and of phenotypic assessment methods at the neural systems level will facilitate the reliable identification of novel memory-related genes. Importantly, a necessary crosstalk between behavioral genetic studies and investigation of causality by molecular genetic studies will ultimately pave the way towards the identification of biologically important, and hopefully druggable, genes and molecular pathways related to human episodic memory.
journal_name
Trends Cogn Scijournal_title
Trends in cognitive sciencesauthors
Papassotiropoulos A,de Quervain DJdoi
10.1016/j.tics.2011.07.005subject
Has Abstractpub_date
2011-09-01 00:00:00pages
381-7issue
9eissn
1364-6613issn
1879-307Xpii
S1364-6613(11)00147-1journal_volume
15pub_type
杂志文章,评审abstract：:The brain during healthy aging exhibits gradual deterioration of structure but maintains a high level of cognitive ability. These structural changes are often accompanied by reorganization of functional brain networks. Existing neurocognitive theories of aging have argued that such changes are either beneficial or det...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2017.04.007
更新日期：2017-07-01 00:00:00
abstract：:Fifteen years ago, Passingham and colleagues proposed that brain areas can be described in terms of their unique pattern of input and output connections with the rest of the brain, and that these connections are a crucial determinant of their function. We explore how the advent of neuroimaging of connectivity has allo...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2018.08.009
更新日期：2018-11-01 00:00:00
abstract：:Increasingly, online platforms are being used to deliver psychotherapy. This, along with the growth in computational psychiatry, provides scientists with new opportunities to quantify how patient-therapist relationships relate to treatment outcomes. We argue that it is necessary to investigate markers and mechanisms t...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2020.10.001
更新日期：2021-01-01 00:00:00
abstract：:The inaugural Australian workshop in Artificial Life took place on the 11th of December 2001 at Adelaide University in South Australia. ...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/s1364-6613(00)01855-6
更新日期：2002-03-01 00:00:00
abstract：:Artificial life provides important theoretical and methodological tools for the investigation of Piaget's developmental theory. This new method uses artificial neural networks to simulate living phenomena in a computer. A recent study by Parisi and Schlesinger suggests that artificial life might reinvigorate the Piage...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/s1364-6613(03)00034-2
更新日期：2003-04-01 00:00:00
abstract：:It is argued here that cognitive science currently neglects an important source of insight into the human mind: the effects created by magicians. Over the centuries, magicians have learned how to perform acts that are perceived as defying the laws of nature, and that induce a strong sense of wonder. This article argue...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2008.05.008
更新日期：2008-09-01 00:00:00
abstract：:Self-control refers to the mental processes that allow people to override thoughts and emotions, thus enabling behavior to vary adaptively from moment to moment. Dominating contemporary research on this topic is the viewpoint that self-control relies upon a limited resource, such that engaging in acts of restraint dep...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2013.12.009
更新日期：2014-03-01 00:00:00
abstract：:In this Opinion article we describe a theory that the brain mechanisms underlying working memory for novel information include a buffer in parahippocampal cortices. Computational modeling indicates that mechanisms for maintaining novel information in working memory could differ from mechanisms for maintaining familiar...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2006.09.005
更新日期：2006-11-01 00:00:00
abstract：:The development of decoding skills has traditionally been viewed as a stage-like process during which children's reading strategies change as a consequence of the acquisition of phonological awareness. More explicit accounts of the mechanisms involved in learning to read are provided by recent connectionist models in ...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/S1364-6613(97)89053-5
更新日期：1997-06-01 00:00:00
abstract：:We describe two merging lines of empirical inquiry: entire false memories for autobiographical events and false confessions. A recent study showed that people can be led to remember, and confess to, perpetrating serious crimes that never occurred when confronted with suggestive interview tactics commonly used in polic...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2015.08.014
更新日期：2015-12-01 00:00:00
abstract：:Psychiatric and neurological disorders have historically provided key insights into the structure-function relationships that subserve human social cognition and behavior, informing the concept of the 'social brain'. In this review, we take stock of the current status of this concept, retaining a focus on disorders th...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2012.09.006
更新日期：2012-11-01 00:00:00
abstract：:Computational models of human collective behavior offer promise in providing quantitative and empirically verifiable accounts of how individual decisions lead to the emergence of group-level organizations. Agent-based models (ABMs) describe interactions among individual agents and their environment, and provide a proc...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2005.07.009
更新日期：2005-09-01 00:00:00
abstract：:Since its inception, the contextual cueing (CC) paradigm has generated considerable interest in various fields of cognitive sciences because it constitutes an elegant approach to understanding how statistical learning (SL) mechanisms can detect contextual regularities during a visual search. In this article we review ...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2015.07.009
更新日期：2015-09-01 00:00:00
abstract：:Perceptual learning can be defined as practice-induced improvement in the ability to perform specific perceptual tasks. We previously proposed the Reverse Hierarchy Theory as a unifying concept that links behavioral findings of visual learning with physiological and anatomical data. Essentially, it asserts that learni...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2004.08.011
更新日期：2004-10-01 00:00:00
abstract：:The perirhinal cortex is known to play a role in recognition memory and visual perception of objects. A recent single-unit recording study adds to our understanding of perirhinal cortex function, suggesting that it may also play a role in evaluating the significance of objects in a context-dependent manner. ...
journal_title：Trends in cognitive sciences
pub_type： 评论,杂志文章
doi：10.1016/j.tics.2015.04.008
更新日期：2015-06-01 00:00:00
abstract：:Recent discoveries about the neural system and cellular mechanisms in pathways mediating classical fear conditioning have provided a foundation for pursuing concurrent connectionist models of this form of emotional learning. The models described are constrained by the known anatomy underlying the behavior being simula...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/S1364-6613(97)01007-3
更新日期：1997-04-01 00:00:00
abstract：:In cognitive neuroscience, brain-behaviour relationships are usually mapped onto a 2D cortical sheet. Cortical layers are a critical but often ignored third dimension of human cortical function. Improved resolution has put us on the threshold of beginning to image human cognition in three dimensions. ...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2018.08.010
更新日期：2018-12-01 00:00:00
abstract：:Recent claims of culture in great apes have provoked fervent argument about the 'true' definition of culture, most of which has been unhelpful. Instead, a range of definitions should be used to explore different aspects of the cognitive processes that together result in human culture, many of which can be productively...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2004.06.002
更新日期：2004-08-01 00:00:00
abstract：:The comparative study of infant development and animal cognition brings to cognitive science the promise of insights into the nature and origins of cognitive skills. In this article, I review a recent wave of comparative studies conducted with similar methodologies and similar theoretical frameworks on how two core co...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2005.01.004
更新日期：2005-03-01 00:00:00
abstract：:The notion of a level of consciousness is a key construct in the science of consciousness. Not only is the term employed to describe the global states of consciousness that are associated with post-comatose disorders, epileptic absence seizures, anaesthesia, and sleep, it plays an increasingly influential role in theo...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2016.03.009
更新日期：2016-06-01 00:00:00
abstract：:'Toward a Science of Consciousness' was held in Skövde, Sweden, from 6-11 August 2001. The meeting was hosted by the University of Skövde, and the theme of this year's conference was 'Consciousness and its Place in Nature'. ...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/s1364-6613(00)01797-6
更新日期：2001-11-01 00:00:00
abstract：:How do the anatomically consistent functional selectivities of the brain emerge? A new study by Bola and colleagues reveals task selectivity in auditory rhythm-selective areas in congenitally deaf adults perceiving visual rhythm sequences. Here, we contextualize this result with accumulating evidence from animal and h...
journal_title：Trends in cognitive sciences
pub_type： 评论,杂志文章
doi：10.1016/j.tics.2017.03.007
更新日期：2017-05-01 00:00:00
abstract：:Music and speech share many acoustic cues but not all are equally important. For example, harmonic pitch is essential for music but not for speech. When birds communicate is their song more like speech or music? A new study contrasting pitch and spectral patterns shows that birds perceive their song more like humans p...
journal_title：Trends in cognitive sciences
pub_type： 评论,杂志文章
doi：10.1016/j.tics.2016.02.004
更新日期：2016-04-01 00:00:00
abstract：:"Executive function" is an umbrella term for functions such as planning, working memory, impulse control, inhibition and mental flexibility, as well as for the initiation and monitoring of action. The primacy of executive dysfunction in autism is a topic of much debate, as are recent attempts to examine subtypes of ex...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2003.11.003
更新日期：2004-01-01 00:00:00
abstract：:A new brain imaging study demonstrates that patients with autism have a strikingly different pattern of brain activity compared with control subjects. During cognitive tasks, cortical areas known as the "default state" network--areas that have been implicated in both self-referential processing and processing of socia...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2006.08.002
更新日期：2006-10-01 00:00:00
abstract：:Understanding a sentence requires a working memory of the partial products of comprehension, so that linguistic relations between temporally distal parts of the sentence can be rapidly computed. We describe an emerging theoretical framework for this working memory system that incorporates several independently motivat...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2006.08.007
更新日期：2006-10-01 00:00:00
abstract：:The manner by which the human brain learns and recognizes stimuli is a matter of ongoing investigation. Through examination of meta-analyses of task-based functional MRI and resting state functional connectivity MRI, we identified a novel network strongly related to learning and memory. Activity within this network at...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2015.07.004
更新日期：2015-09-01 00:00:00
abstract：:From the noisy information bombarding our senses, our brains must construct percepts that are veridical - reflecting the true state of the world - and informative - conveying what we did not already know. Influential theories suggest that both challenges are met through mechanisms that use expectations about the likel...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2019.11.003
更新日期：2020-01-01 00:00:00
abstract：:Neural coding by brain oscillations is a major focus in neuroscience, with important implications for dyslexia research. Here, I argue that an oscillatory 'temporal sampling' framework enables diverse data from developmental dyslexia to be drawn into an integrated theoretical framework. The core deficit in dyslexia is...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章
doi：10.1016/j.tics.2010.10.001
更新日期：2011-01-01 00:00:00
abstract：:Brain evolution has often been correlated with the cognitive demands of social life. Further progress depends on our ability to link cognitive processes to corresponding brain part sizes and structures, and, ultimately, to demonstrate causality. Recent research suggests that fishes are suitable to test general hypothe...
journal_title：Trends in cognitive sciences
pub_type： 杂志文章,评审
doi：10.1016/j.tics.2014.04.005
更新日期：2014-09-01 00:00:00
