Abstract:
:In this Perspective, we summarize some of the most contentious issues surrounding diagnosis and treatment of myeloma. We outline how a fundamental clash of philosophies, cure versus control, may be at the heart of many of the controversies. From the very definition of the disease to risk stratification to the validity of current clinical trial endpoints, we highlight the major areas of debate and provide alternative viewpoints that have implications for trial design and interpretation, as well as clinical practice.
journal_name
Bloodjournal_title
Bloodauthors
Rajkumar SV,Gahrton G,Bergsagel PLdoi
10.1182/blood-2011-06-297853subject
Has Abstractpub_date
2011-09-22 00:00:00pages
3205-11issue
12eissn
0006-4971issn
1528-0020pii
blood-2011-06-297853journal_volume
118pub_type
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