A method for estimating vaccine-preventable pediatric influenza pneumonia hospitalizations in developing countries: Thailand as a case study.

abstract：BACKGROUND:Streptococcus pyogenes (group A Streptococcus, Strep A) is a widespread pathogen that continues to pose a significant threat to human health. The development of a Strep A vaccine remains an unmet global health need. One of the major vaccine strategies is the use of M protein, which is a primary virulence det...

journal_title：Vaccine

authors： Pastural É,McNeil SA,MacKinnon-Cameron D,Ye L,Langley JM,Stewart R,Martin LH,Hurley GJ,Salehi S,Penfound TA,Halperin S,Dale JB

更新日期：2020-02-05 00:00:00

abstract：:Mucosal but not parenteral vaccination with whole Leishmania amazonensis promastigotes antigens (LaAg) is known to increase host resistance to infection by an as yet unknown immune mechanism. Since early immune responses are critical for infection establishment, in the present study the differential responses elicited...

journal_title：Vaccine

authors： Pereira Silva Bezerra I,Amaral Abib M,Rossi-Bergmann B

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:This study examined the transmissibility between young children of an intranasally administered live attenuated human parainfluenza virus type 3 (HPIV3)-cp45 vaccine candidate. METHODS:Eighty subjects were enrolled in playgroups among whom there was at least one infected vaccinee in close contact with a ser...

journal_title：Vaccine

authors： Madhi SA,Cutland C,Zhu Y,Hackell JG,Newman F,Blackburn N,Murphy BR,Belshe RB,Karron RA,Deatly AM,Gruber WC,Bernstein DI,Wright PF

更新日期：2006-03-20 00:00:00

abstract：:Our current knowledge allows the generation of transgenic plants that efficiently produce heterologous proteins from plant, bacterial, fungal or animal origin. Among all types of recombinant proteins, antibodies are particularly attractive because of their ability to specifically recognize and bind virtually any type ...

journal_title：Vaccine

authors： Peeters K,De Wilde C,De Jaeger G,Angenon G,Depicker A

更新日期：2001-03-21 00:00:00

abstract：:Bovine tuberculosis (bTB) is increasing in incidence in the UK. Effective control strategies could involve vaccination; BCG, either alone or in prime-boost strategies, remains the most effective vaccine against bovine tuberculosis. However, BCG vaccination of cattle would require development of diagnostic tests able t...

journal_title：Vaccine

authors： Sopp P,Coad M,Hewinson G,Howard CJ,Cheallaigh CN,Keane J,Harris J,Hope JC

更新日期：2008-10-09 00:00:00

abstract：:Pseudomonas aeruginosa antimicrobial resistance is a major therapeutic challenge. DNA vaccination is an attractive approach for antigen-specific immunotherapy against P. aeruginosa. We explored the feasibility of employing Herpes simplex virus type 1 tegument protein, VP22, as a molecular tool to enhance the immunogen...

journal_title：Vaccine

authors： Yu X,Wang Y,Xia Y,Zhang L,Yang Q,Lei J

更新日期：2016-08-17 00:00:00

abstract：:A randomized, double-blind, controlled clinical trial was conducted to evaluate the efficacy and safety of CJ-50300, a newly developed cell culture-derived smallpox vaccine, and to determine its minimum effective dose. The overall rates of cutaneous "take" reaction and humoral and cellular immunogenicity in CJ-50300 v...

journal_title：Vaccine

authors： Jang HC,Kim CJ,Kim KH,Lee KH,Byun YH,Seong BL,Saletti G,Czerkinsky C,Park WB,Park SW,Kim HB,Kim NJ,Oh MD

更新日期：2010-08-16 00:00:00

abstract：BACKGROUND:Implementation of 7-valent pneumococcal conjugate vaccine (PCV7) in the Dutch national immunization program for infants led to a shift from vaccine to non-vaccine serotypes in invasive pneumococcal disease (IPD) in all age groups. We studied the impact of the serotype shift on clinical syndromes and outcomes...

journal_title：Vaccine

authors： Wagenvoort GH,Sanders EA,Vlaminckx BJ,Elberse KE,de Melker HE,van der Ende A,Knol MJ

更新日期：2016-02-17 00:00:00

abstract：:Mycobacterium w (Mw), is a cultivable, non-pathogenic mycobacterium and has been tried extensively as an immunomodulator in leprosy. This has been found to be safe and has shown beneficial immunoprophylactic effect in population based, double blind placebo controlled trials in North India. These effects were also obse...

journal_title：Vaccine

authors： Katoch K,Singh P,Adhikari T,Benara SK,Singh HB,Chauhan DS,Sharma VD,Lavania M,Sachan AS,Katoch VM

更新日期：2008-02-26 00:00:00

abstract：:The goal of the present study was to evaluate the influence of the influenza A H1N1/2009 vaccine on dermatomyositis/polymyositis (DM/PM) disease parameters and the potential deleterious effect of therapy on immune response. Thirty-seven DM and 21 PM patients (Bohan and Peter's criteria) were gender- and age-matched to...

journal_title：Vaccine

authors： Shinjo SK,de Moraes JC,Levy-Neto M,Aikawa NE,de Medeiros Ribeiro AC,Schahin Saad CG,Precioso A,Silva CA,Bonfá E

更新日期：2012-12-17 00:00:00

abstract：:Varied doses of Taishan Pinus massoniana pollen polysaccharide (TPPPS) and Astragalus polysaccharide (APS) extracted by hot water extraction and ethanol precipitation method were added to the vaccine in order to prepare polysaccharide-rabbit haemorrhagic disease (RHD) tissue inactivated vaccine. The purpose was to stu...

journal_title：Vaccine

authors： Wei K,Sun Z,Yan Z,Tan Y,Wang H,Zhu X,Wang X,Sheng P,Zhu R

更新日期：2011-03-21 00:00:00

abstract：:In Japan, trivalent inactivated influenza vaccine is the only approved influenza vaccine. It is typically administrated by hypodermic injection, and children under 13 years of age are recommended to be vaccinated two times during each winter season. Live-attenuated influenza vaccine (LAIV) is administered by a thimero...

journal_title：Vaccine

authors： Shono A,Kondo M

更新日期：2014-09-03 00:00:00

abstract：:Since vaccination against human papillomavirus (HPV) became available, awareness of HPV has dramatically increased. Implementation of a vaccine program varies internationally yet no studies have explored the influence this has on the public's knowledge of HPV. The present study aimed to explore differences in awarenes...

journal_title：Vaccine

authors： Marlow LA,Zimet GD,McCaffery KJ,Ostini R,Waller J

更新日期：2013-01-21 00:00:00

abstract：:Pertussis vaccine development has mainly focused on Bordetella pertussis, and consequently these vaccines contain B. pertussis antigens only. However, the related species Bordetella parapertussis can also cause pertussis, although symptoms associated with the disease are generally considered to be milder. Recent field...

journal_title：Vaccine

authors： David S,van Furth R,Mooi FR

更新日期：2004-05-07 00:00:00

abstract：:It is of paramount importance to know the vaccination status in internationally adopted children, so that they can be correctly immunized. This study ascertains the seroprotection rate for vaccine-preventable diseases and the validity of the immunization cards in 637 adopted children. The absence of the immunization c...

journal_title：Vaccine

authors： Cilleruelo MJ,de Ory F,Ruiz-Contreras J,González-González R,Mellado MJ,García-Hortelano M,Villota J,García-Ascaso M,Piñeiro R,Martín-Fontelos P,Herruzo R

更新日期：2008-10-29 00:00:00

abstract：:We have demonstrated that vaccination of turkeys with an unformulated DNA vaccine induces significant protection against Chlamydophila (Cp.) psittaci infections. Nevertheless, the immunogenicity of the DNA vaccine can still be improved by increasing translation and transfection efficiency. Therefore, the ompA codon wa...

journal_title：Vaccine

authors： Verminnen K,Beeckman DS,Sanders NN,De Smedt S,Vanrompay DC

更新日期：2010-04-19 00:00:00

abstract：:Experimental whole-parasite immunization through concurrent administration of infectious Plasmodium sporozoites with drugs that prevent pathogenic blood-stage infection represents the current benchmark in malaria vaccine development. Key questions concerning translation remain, including the requirement for single-dos...

journal_title：Vaccine

authors： Pfeil J,Sepp KJ,Heiss K,Meister M,Mueller AK,Borrmann S

更新日期：2014-10-14 00:00:00

abstract：:Live, attenuated hepatitis A vaccines are used widely in China but there is uncertainty regarding the persistence of vaccine-induced anti-HAV antibodies after single dose and booster dose administrated at month 12. A large scale clinical trial to evaluate the live, attenuated hepatitis A vaccine was conducted in Hebei...

journal_title：Vaccine

authors： Wang XY,Xu ZY,Ma JC,von Seidlein L,Zhang Y,Hao ZY,Han OP,Zhang YL,Tian MY,Ouyang PY,Zhang ZY,Han CQ,Xing ZC,Chen JC

更新日期：2007-01-05 00:00:00

abstract：:We constructed double deletion (ΔcydCΔcydD and ΔcydCΔpurD) mutants from virulent Brucella abortus biovar 1 field isolate (BA15) by deleting the genes encoding an ATP-binding cassette-type transporter (cydC and cydD genes) and a phosphoribosylamine-glycine ligase (purD). Both BA15ΔcydCΔcydD and BA15ΔcydCΔpurD double-mu...

journal_title：Vaccine

authors： Truong QL,Cho Y,Park S,Kim K,Hahn TW

更新日期：2016-01-04 00:00:00

abstract：:The effect of sublethal gamma-ray irradiation on the protection conferred by a nasal influenza vaccine was investigated in BALB/c mice. A radiation dose of 7 Gy was selected as the sublethal dose as this caused exacerbation of the influenza but was not lethal in the mouse model. Mice were irradiated 7 days before, on ...

journal_title：Vaccine

authors： Hasegawa H,Kadowaki S,Takahashi H,Iwasaki T,Tamura S,Kurata T

更新日期：2000-05-22 00:00:00

abstract：:Livestock production is a fundamental source of revenue and nutrition, wherein cattle-farming constitutes one of the major agricultural industries. Vectors and vector-borne diseases constitute one of the major factors that decrease the livelihood of all farming communities, more so in resource-poor communities and dev...

journal_title：Vaccine

authors： Robbertse L,Richards SA,Stutzer C,Olivier NA,Leisewitz AL,Crafford JE,Maritz-Olivier C

更新日期：2020-10-14 00:00:00

abstract：:For infants immunized with Haemophilus influenzae type b conjugate vaccines, booster immunization is usually recommended in the second year of life, typically between 12 and 18 months. This study assessed the effect of age at booster immunization on pre-immunization antibody trough levels and on subsequent responses, ...

journal_title：Vaccine

authors： Scheifele DW,Guasparini R,Lavigne P

更新日期：1999-02-12 00:00:00

abstract：:This commentary is a response to a systematic review, recently published in Vaccine, which investigates the effectiveness of educational interventions in increasing uptake of the human papillomavirus vaccine. The systematic review by Fu et al. (2014) enhances the field's understanding of human papillomavirus vaccine i...

journal_title：Vaccine

authors： Shapiro GK,Joyal-Desmarais K,Perez S,Rosberger Z

更新日期：2014-11-12 00:00:00

abstract：:Age-specific force of varicella infection, hospitalisation and death rates in non-immune persons were calculated using an age-based mathematical model and national data for France. A cost-effectiveness model was then applied to hypothetical cohorts of persons aged 15-45 years with a negative or uncertain history of va...

journal_title：Vaccine

authors： Hanslik T,Boëlle PY,Schwarzinger M,Carrat F,Freedberg KA,Valleron AJ,Flahault A

更新日期：2003-09-08 00:00:00

abstract：:The adjuvant properties of polyglucosamine/squalene-based nanocapsules (PG-nanocapsules) associated with different subunit antigens has been previously reported. Thus, the aim of the present study was to monitor the biodistribution of PG-nanocapsules and their affinity for the draining lymph nodes after subcutaneous (...

journal_title：Vaccine

authors： Vicente S,Goins BA,Sanchez A,Alonso MJ,Phillips WT

更新日期：2014-03-26 00:00:00

abstract：:Viral hepatitis remains a major contributor to the global disease burden. Mass immunisation strategies against hepatitis B have been adopted by more than 90 developing and industrialised countries. Countries with low hepatitis A endemicity are experiencing cyclical outbreaks and an epidemiological shift, with larger n...

journal_title：Vaccine

authors： Lopalco PL,Salleras L,Barbuti S,Germinario C,Bruguera M,Buti M,Domínguez A

更新日期：2000-10-15 00:00:00

abstract：:The vast majority of vaccines used throughout the world are supplied by the private sector. It is essential therefore that the industry is closely engaged in future policy developments at a national and international level and is able to respond to the changing needs and priorities that may be required to ensure the s...

journal_title：Vaccine

authors： Almond J,Medaglini D

更新日期：2017-01-20 00:00:00

abstract：:The aim of the study was to analyze the impact of MenBvac, an outer membrane vesicle (OMV) vaccine against P1.7,16 strains, on meningococcal carriage. During a B:14:P1.7,16/ST-32 outbreak in Normandy (France), children aged 1-7 years were randomly selected to participate in the study. Among the 1082 volunteers, there ...

journal_title：Vaccine

authors： Delbos V,Lemée L,Bénichou J,Berthelot G,Deghmane AE,Leroy JP,Houivet E,Hong E,Taha MK,Caron F,B14 STOP study group.

更新日期：2013-09-13 00:00:00

abstract：:This work describes the nature and strength of the immune response induced by various Toll-like receptor ligands and their ability to act as vaccine adjuvants. It reviews the various ligands capable of triggering individual TLRs, and then focuses on the efficacy and safety of those agents for which clinical results ar...

journal_title：Vaccine

authors： Steinhagen F,Kinjo T,Bode C,Klinman DM

更新日期：2011-04-12 00:00:00

abstract：:In this article, we review three mechanisms that contribute to sustaining serum antibody levels: (i) long-lived plasma cells; (ii) persisting or cross-reactive antigen, and (iii) polyclonal activation of all memory B cells. We also present a quantitative analysis of the secondary immune response that reveals the relat...

journal_title：Vaccine

authors： Traggiai E,Puzone R,Lanzavecchia A

更新日期：2003-06-01 00:00:00