Outcome of surgical treatment of peri-implantitis: results from a 2-year prospective clinical study in humans.

Abstract:

AIM:The aim of the present study was to evaluate the outcome of a surgical procedure based on pocket elimination and bone re-contouring for the treatment of peri-implantitis. MATERIAL AND METHODS:The 31 subjects involved in this study presented clinical signs of peri-implantitis at one or more dental implants (i.e. ≥6 mm pockets, bleeding on probing and/or suppuration and radiographic evidence of ≥2 mm bone loss). The patients were treated with a surgical procedure based on pocket elimination and bone re-contouring and plaque control before and following the surgery. At the time of surgery, the amount of bone loss at implants was recorded. RESULTS:Two years following treatment, 15 (48%) subjects had no signs of peri-implant disease; 24 patients (77%) had no implants with a probing pocket depth of ≥6 mm associated with bleeding and/or suppuration following probing. A total of 36 implants (42%) out of the 86 with initial diagnosis of peri-implantitis presented peri-implant disease despite treatment. The proportion of implants that became healthy following treatment was higher for those with minor initial bone loss (2-4 mm bone loss as assessed during surgery) compared with the implants with a bone loss of ≥5 mm (74% vs. 40%). Among the 18 implants with bone loss of ≥7 mm, seven were extracted. Between the 6-month and the 2-year examination, healthy implants following treatment tended to remain stable, while deepening of pockets was observed for those implants with residual pockets. CONCLUSION:The results of this study indicated that a surgical procedure based on pocket elimination and bone re-contouring and plaque control before and following surgery was an effective therapy for treatment of peri-implantitis for the majority of subjects and implants. However, complete disease resolution at the site level seems to depend on the initial bone loss at implants. Implants with no signs of peri-implantitis following treatment tended to remain healthy during the 2-year period, while a tendency for disease progression was observed for the implants that still showed signs of peri-implant disease following treatment.

journal_name

Clin Oral Implants Res

authors

Serino G,Turri A

doi

10.1111/j.1600-0501.2010.02098.x

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1214-20

issue

11

eissn

0905-7161

issn

1600-0501

journal_volume

22

pub_type

杂志文章
  • Effect of surface topography of screw-shaped titanium implants in humans on clinical and radiographic parameters: a 12-year prospective study.

    abstract:OBJECTIVES:Although implants with a roughened surface are widely used today, little is known about the long-term effect of a roughened surface compared with the conventional machined surface on clinical and radiographic parameters. The purpose of this study is to investigate the long-term differences between moderately...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2009.01768.x

    authors: Vroom MG,Sipos P,de Lange GL,Gründemann LJ,Timmerman MF,Loos BG,van der Velden U

    更新日期:2009-11-01 00:00:00

  • The effect of oestrogen and alendronate therapies on postmenopausal bone loss around osseointegrated titanium implants.

    abstract:OBJECTIVES:This study evaluated the influence of oestrogen deficiency and its therapies on bone tissue around osseointegrated implants. METHODS:Implants were placed in 66 female rats tibiae. The animals were assigned into five groups: control (CTL), sham, ovariectomy (OVX), oestrogen (EST), and alendronate (ALE). Whil...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.01989.x

    authors: Giro G,Coelho PG,Pereira RM,Jorgetti V,Marcantonio E Jr,Orrico SR

    更新日期:2011-03-01 00:00:00

  • Hydrophilic titanium surface-induced macrophage modulation promotes pro-osteogenic signalling.

    abstract:OBJECTIVES:As biomaterial-induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. MATERIAL AND METHODS:Rodent bone marrow-der...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13522

    authors: Hamlet SM,Lee RSB,Moon HJ,Alfarsi MA,Ivanovski S

    更新日期:2019-11-01 00:00:00

  • Six-year clinical outcome of single implant-retained mandibular overdentures--a pilot study.

    abstract:OBJECTIVES:The aim of this prospective pilot study was to evaluate the prosthodontic maintenance as well as the implant outcome of single implant-retained mandibular overdentures over an observation period of 6 years. METHODS:Eleven edentulous patients received one single implant in the midline of the mandible. Dentur...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12427

    authors: Passia N,Wolfart S,Kern M

    更新日期:2015-10-01 00:00:00

  • Vertical palatal bone dimensions on lateral cephalometry and cone-beam computed tomography: implications for palatal implant placement.

    abstract:OBJECTIVES:To evaluate the necessity of three-dimensional imaging (computed tomography [CT]/cone-beam computed tomography [CBCT]) for paramedian insertion of palatal implants. MATERIAL AND METHODS:Lateral radiographs and CBCT scans were performed from 18 human skulls. For lateral cephalometry, the nasal floor (right/l...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02021.x

    authors: Jung BA,Wehrbein H,Heuser L,Kunkel M

    更新日期:2011-06-01 00:00:00

  • Characterization of novel silane coatings on titanium implant surfaces.

    abstract:OBJECTIVES:This in vitro study describes and characterizes a developed novel method to produce coatings on Ti. Hydrophobic coatings on substrates are needed in prosthetic dentistry to promote durable adhesion between luting resin cements and coated Ti surfaces. In implant dentistry the hydrophobic coatings on a Ti impl...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2012.02504.x

    authors: Matinlinna JP,Tsoi JK,de Vries J,Busscher HJ

    更新日期:2013-06-01 00:00:00

  • Incomplete bone regeneration of rabbit calvarial defects using different membranes.

    abstract::The present study describes the use of a degradable and a non-degradable material for guided bone regeneration. Forty rabbits were divided into 5 groups. Bicortical defects 15 mm in diameter were prepared in rabbit calvaria. A titanium microplate was placed over the defect to prevent collapse of the membrane. The calv...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1998.090504.x

    authors: Aaboe M,Pinholt EM,Schou S,Hjørting-Hansen E

    更新日期:1998-10-01 00:00:00

  • Adhesion pattern and growth of primary human osteoblastic cells on five commercially available titanium surfaces.

    abstract:OBJECTIVE:The aim of this study is to analyze the morphology and proliferation of human osteoblastic cells in vitro on five commercially available titanium surfaces. MATERIALS AND METHODS:Human primary cells of the osteoblastic lineage were obtained from bone explants. The cells were plated on polished (T1), machined ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2009.01906.x

    authors: Passeri G,Cacchioli A,Ravanetti F,Galli C,Elezi E,Macaluso GM

    更新日期:2010-07-01 00:00:00

  • Osseointegration of commercial microstructured titanium implants incorporating magnesium: a histomorphometric study in rabbit cancellous bone.

    abstract:OBJECTIVE:Recent studies have suggested that magnesium (Mg) ions exert a beneficial effect on implant osseointegration. This study assessed the osseointegration of nanoporous titanium (Ti) surface incorporating the Mg produced by hydrothermal treatment in rabbit cancellous bone to determine whether this surface would f...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02144.x

    authors: Park JW,An CH,Jeong SH,Suh JY

    更新日期:2012-03-01 00:00:00

  • Implant treatment in immunosuppressed renal transplant patients: A prospective case-controlled study.

    abstract:OBJECTIVES:The aim of this clinical study was to evaluate long-term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. MATERIAL AND METHODS:Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 20...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13437

    authors: Hernández G,Paredes V,López-Pintor RM,de Andrés A,de Vicente JC,Sanz M

    更新日期:2019-06-01 00:00:00

  • Biofilm removal from implants supported restoration using different instruments: a 6-month comparative multicenter clinical study.

    abstract:OBJECTIVES:The aim of this study was to compare the efficacy of different instruments on biofilm removal from implant supported restorations. MATERIALS AND METHODS:The study was designed as comparative multicenter clinical study including patients proceeding from the Milan, Naples, and Buenos Aires, with a peri-implan...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,多中心研究

    doi:10.1111/clr.12530

    authors: Blasi A,Iorio-Siciliano V,Pacenza C,Pomingi F,Matarasso S,Rasperini G

    更新日期:2016-02-01 00:00:00

  • Comparative maxillary bone-defect healing by calcium-sulphate or deproteinized bovine bone particles and extra cellular matrix membranes in a guided bone regeneration setting: an experimental study in rabbits.

    abstract:OBJECTIVES:The aim of this study was to histologically compare the dynamics of bone healing response between calcium sulphate (CaS) and deproteinized bovine bone mineral (DBBM) particles in guided bone regeneration utilizing an extracellular matrix membrane (ECM) as barrier. MATERIALS AND METHODS:Eighteen rabbits were...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12425

    authors: Turri A,Dahlin C

    更新日期:2015-05-01 00:00:00

  • Esthetic, clinical and patient-centered outcomes of immediately placed implants (Type 1) and early placed implants (Type 2): preliminary 3-month results of an ongoing randomized controlled clinical trial.

    abstract:AIM:The objective of the study was to compare (i) esthetic, (ii) clinical and (iii) patient-centered outcomes following immediate (Type 1) and early implant placement (Type 2). MATERIAL AND METHODS:Thirty-eight subjects needing a single extraction (premolar to premolar) were randomly allocated to Type 1 or Type 2 impl...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12577

    authors: Huynh-Ba G,Meister DJ,Hoders AB,Mealey BL,Mills MP,Oates TW,Cochran DL,Prihoda TJ,McMahan CA

    更新日期:2016-02-01 00:00:00

  • Chemical treatment of machined titanium surfaces. An in vitro study.

    abstract::Microbial plaque accumulation on titanium dental implant surfaces can result in an inflammatory condition of the surrounding tissues. Cleaning of such a contaminated surface, in vivo, by means of a solution of amino-alcohol, following surgical exposure, has been proposed. However, the tissue healing following treatmen...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1999.100303.x

    authors: Krozer A,Hall J,Ericsson I

    更新日期:1999-06-01 00:00:00

  • Digital vs. conventional implant prosthetic workflows: a cost/time analysis.

    abstract:OBJECTIVES:The aim of this prospective cohort trial was to perform a cost/time analysis for implant-supported single-unit reconstructions in the digital workflow compared to the conventional pathway. MATERIALS AND METHODS:A total of 20 patients were included for rehabilitation with 2 × 20 implant crowns in a crossover...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12476

    authors: Joda T,Brägger U

    更新日期:2015-12-01 00:00:00

  • Changes in the volume and density of calvarial split bone grafts after alveolar ridge augmentation.

    abstract:OBJECTIVES:One main problem occurring after bone grafting is resorption, leading to insufficient bone volume and quality, and may subsequently cause dental implant failure. Comparison of graft volume and bone density of iliac crest and calvarial transplants determined by animal studies demonstrates significantly lower ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2005.01182.x

    authors: Smolka W,Eggensperger N,Carollo V,Ozdoba C,Iizuka T

    更新日期:2006-04-01 00:00:00

  • Computer-guided implant therapy and soft- and hard-tissue aspects. The Third EAO Consensus Conference 2012.

    abstract:INTRODUCTION:The objectives of this working group were to update the existing knowledge base in computer-guided implant treatment (accuracy and clinical advantages), to search for scientific evidence on the need for keratinized tissue around implants, and to review recent literature in the search for new insights into ...

    journal_title:Clinical oral implants research

    pub_type: 共识发展会议,杂志文章,评审

    doi:10.1111/j.1600-0501.2012.02553.x

    authors: Sicilia A,Botticelli D,Working Group 3.

    更新日期:2012-10-01 00:00:00

  • A randomized controlled trial on the efficiency of free-handed, pilot-drill guided and fully guided implant surgery in partially edentulous patients.

    abstract:OBJECTIVES:To compare the effectiveness of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery by means of the apical global deviation (AGD) in relation to the additional financial cost and time spent. MATERIALS AND METHODS:Thirty-three partially edentulous patients in need of ≥2 implants i...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.13399

    authors: Younes F,Eghbali A,De Bruyckere T,Cleymaet R,Cosyn J

    更新日期:2019-02-01 00:00:00

  • Factors related to peri-implantitis - a retrospective study.

    abstract:OBJECTIVES:Retrospectively, we assessed the likelihood that peri-implantitis was associated with a history of systemic disease, periodontitis, and smoking habits. METHODS:Data on probing pocket depth (PPD), bleeding on probing (BOP), and radiographic bone levels were obtained from individuals with dental implants. Per...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12208

    authors: Renvert S,Aghazadeh A,Hallström H,Persson GR

    更新日期:2014-04-01 00:00:00

  • A fully digital approach to replicate peri-implant soft tissue contours and emergence profile in the esthetic zone.

    abstract:OBJECTIVE:This short communication reports on a novel digital technique designated - the "Fully Digital Technique (FDT)" - to take the impression of the peri-implant soft tissue and emergence profile with an intraoral scanner, digitally capturing both the three dimensional position of the implant platform and the coron...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12599

    authors: Monaco C,Evangelisti E,Scotti R,Mignani G,Zucchelli G

    更新日期:2016-12-01 00:00:00

  • Characterization, at the bone crystal level, of the titanium-coating/bone interfacial zone.

    abstract::Well integrated and clinically functional titanium dental implants retrieved in humans after 14 and 40 months of settlement were used for the characterization of the interfacial area between the plasma-sprayed coating and the surrounding mineralized bone. Electron microscopic studies were performed from undecalcified ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2000.011004279.x

    authors: Leize EM,Hemmerlé J,Leize M

    更新日期:2000-08-01 00:00:00

  • GSK3b-inhibitor lithium chloride enhances activation of Wnt canonical signaling and osteoblast differentiation on hydrophilic titanium surfaces.

    abstract:AIMS:Promoting bone formation at the tissue interface is an important step to improve implant success. This study investigated whether stimulation of Wnt signaling by GSK3b inhibitor lithium chloride (LiCl) could affect the response of mesenchymal or osteoblastic cells growing on titanium surfaces with different topogr...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2012.02488.x

    authors: Galli C,Piemontese M,Lumetti S,Manfredi E,Macaluso GM,Passeri G

    更新日期:2013-08-01 00:00:00

  • Sinus augmentation via transcrestal approach: a comparison between the balloon and osteotome technique in a cadaver study.

    abstract:BACKGROUND:The transcrestal approach with osteotomes is a commonly applied and predictable technique for maxillary sinus floor elevation. However, Schneiderian membrane perforation is a common and often inevitable intraoperative complication. Recently, the use of balloons has been proposed to reduce the risk of sinus m...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2012.02506.x

    authors: Chan HL,Oh TJ,Fu JH,Benavides E,Avila-Ortiz G,Wang HL

    更新日期:2013-09-01 00:00:00

  • Professional and patient-based evaluation of oral rehabilitation in patients with tooth agenesis.

    abstract:OBJECTIVES:The outcome of oral rehabilitation is usually monitored with clinical tests rather than by patient's perception of change. The aim of this study was to describe the objective measure and subjective perception of oral rehabilitation in patients with tooth agenesis. MATERIAL AND METHODS:The study included 129...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2008.01698.x

    authors: Dueled E,Gotfredsen K,Trab Damsgaard M,Hede B

    更新日期:2009-07-01 00:00:00

  • Implants placed in fresh extraction sockets in the maxilla: clinical and radiographic outcomes from a 3-year follow-up examination.

    abstract:AIM:The aim of this prospective, randomized, controlled multicenter study was to determine the 3-year efficacy and stability of the soft and hard tissues at implants with a different geometry that were placed in fresh extraction sockets. MATERIAL AND METHODS:Implants with two different configurations, cylindrical (Gro...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/clr.12140

    authors: Sanz M,Cecchinato D,Ferrus J,Salvi GE,Ramseier C,Lang NP,Lindhe J

    更新日期:2014-03-01 00:00:00

  • Crestal bone changes in macrogeometrically similar implants with the implant-abutment connection at the crestal bone level or 2.5 mm above: a prospective randomized clinical trial.

    abstract:OBJECTIVE:Crestal bone loss around dental implants is a criterion for success as this could prevent loss of implant and superstructure. The macrogeometry of the implant could influence bone remodelling when the implant-abutment connection is placed at crestal bone level or above. The aim of this study was to evaluate c...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12581

    authors: van Eekeren P,Tahmaseb A,Wismeijer D

    更新日期:2016-12-01 00:00:00

  • A 5- to 6-year radiological evaluation of titanium plasma sprayed/sandblasted and acid-etched implants: results from private practice.

    abstract:OBJECTIVES:This study aimed to determine bone level changes after 5-6 years of follow-up for a large group of one-stage dental implants consecutively placed in private practice. Potential confounding factors influencing crestal bone loss (CBL) were also assessed. MATERIALS AND METHODS:A total of 378 transmucosal Strau...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12083

    authors: Dam HG,Najm SA,Nurdin N,Bischof M,Finkelman M,Nedir R

    更新日期:2014-02-01 00:00:00

  • Changes in alveolar process dimensions following extraction of molars with advanced periodontal disease: A clinical pilot study.

    abstract:OBJECTIVE:To use cone beam computed tomography (CBCT) to assess the alterations of socket dimensions after a 6-month healing period following molar extraction. MATERIALS AND METHODS:Seventeen molars were extracted due to advanced periodontitis. CBCT scans were taken immediately after extraction and once more 6 months ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13418

    authors: Zhao L,Wei Y,Xu T,Zhang B,Hu W,Chung KH

    更新日期:2019-04-01 00:00:00

  • Enamel matrix derivative in liquid form as adjunct to natural bovine bone grafting at buccal bone dehiscence defects at implant sites: An experimental study in beagle dogs.

    abstract:OBJECTIVES:To evaluate the effect of enamel matrix derivative in liquid form (EMD-liquid) as adjunct to grafting with natural bovine bone (NBB), on new bone formation and osseointegration in buccal dehiscence defects at dental implants. MATERIAL AND METHODS:In six beagles, 3 months after extraction of the mandibular p...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13512

    authors: Ikawa T,Akizuki T,Shujaa Addin A,Fukuba S,Stavropoulos A,Izumi Y

    更新日期:2019-10-01 00:00:00

  • Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants.

    abstract::It has been postulated that the wound healing in a closed submerged location is one of the prerequisites for osseointegration of dental implants. The purpose of the present study was to evaluate the tissue integration of intentionally non-submerged titanium implants inserted by a one-stage surgical procedure. 100 ITI ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1990.010105.x

    authors: Buser D,Weber HP,Lang NP

    更新日期:1990-12-01 00:00:00