Abstract:
AIM OF STUDY:Few studies have evaluated the incidence of familial vesicoureteral reflux (VUR) among multiple gestation births. The purpose of this study was to determine the incidence and characteristics of VUR in twins in a large cohort of families with VUR. METHODS:Between 1998 and 2010, data were collected on 251 families (538 children) with at least 2 siblings who had VUR. The incidence of affected twins among the families was analysed. Data were assessed for age at presentation, gender, grading of VUR, laterality of affectation and renal scarring. VUR was diagnosed by voiding cystourethrography (VCUG) and dimercaptosuccinic acid (DMSA) scans were used to assess renal scarring. RESULTS:There were 12 families (4.8%) in which twins were affected with VUR. There were 12 index cases (7 males/5 females), and 12 siblings (1 male/11 females). All index cases presented with urinary tract infection (UTIs), whereas 2 siblings had UTIs and 10 were screened. All cases presented between 3 months and 2 years. Among the index cases, three had unilateral and nine had bilateral VUR. Among the siblings, four had unilateral and eight had bilateral VUR. Thirty-seven (90%) of the 41 affected renal refluxing units had high-grade VUR. Three index cases had renal scarring. No scarring was seen in the siblings. CONCLUSIONS:The vast majority of twins with VUR are females who have high grade VUR and a low incidence of renal scarring. Twins with VUR may represent a genetically different subgroup with female preponderance and severe reflux.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Giannotti G,Menezes M,Hunziker M,Puri Pdoi
10.1007/s00383-010-2821-0subject
Has Abstractpub_date
2011-05-01 00:00:00pages
513-5issue
5eissn
0179-0358issn
1437-9813journal_volume
27pub_type
杂志文章abstract::Thyroglossal duct cyst (TGDC) disease, one of the most common developmental neck lesion in the pediatric population, often presents as infected neck mass. The authors reviewed their experience in the management of inflamed TGDC cases, in order to suggest the most efficient approach of these patients regarding the idea...
journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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doi:
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abstract::Congenital obstructive uropathy is associated with significant morbidity and mortality in the human neonate. The pathophysiology of congenital obstructive uropathy is poorly understood. There are very few experimental models of prenatal obstruction of the urinary tract, except in the fetal lamb or inbred rats. Prenata...
journal_title:Pediatric surgery international
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doi:10.1007/s00383-004-1322-4
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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abstract::Congenital arteriovenous fistulas are a rare cause of neck mass in children, but should be considered in the differential diagnosis of paediatric patients presenting with pulsatile neck masses even when there is no history of trauma. Balloon embolisation is the treatment of choice because of the high risk of surgical ...
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1125-z
更新日期:2004-04-01 00:00:00
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journal_title:Pediatric surgery international
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更新日期:1996-03-01 00:00:00
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更新日期:2015-11-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
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更新日期:2020-01-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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abstract::Recently, laparoscopic orchidopexy has been accepted as the standard procedure of management for clinically impalpable testes. However, many techniques have been described for the delivery of the mobilized testes. In this report, a new approach is described. The use of a fourth "scroto-peritoneal" port, makes complete...
journal_title:Pediatric surgery international
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更新日期:1998-07-01 00:00:00
abstract::A reproducible technique was developed experimentally in pigs for construction of a 'composite bowel tube' (CBT) made up of ileal mucosa that was grafted to a mucosally denuded colonic muscle surface vascularised by the colonic mesentery. Macroscopic and microscopic studies at terminal laparotomy revealed a viable, mu...
journal_title:Pediatric surgery international
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doi:10.1007/BF00178430
更新日期:1996-04-01 00:00:00
abstract:INTRODUCTION:No protocol exists for prophylaxis or therapeutic management of peripherally inserted central catheter (PICC) related deep venous thrombosis (DVT) in children. Currently, very few patients are provided prophylaxis for DVT. In this study, we analyzed our current practice of PICC placement to identify the fr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3259-y
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Surgery of the inguinal canal is very common in infancy. Occasionally, injury of the bladder may occur with severe consequences. The aim of this paper was to warn young surgeons of this serious complication. METHODS:During the last 2 years, we observed four cases of bladder injury following surgery on inguinal...
journal_title:Pediatric surgery international
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doi:10.1007/s00383-010-2707-1
更新日期:2010-12-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3621-8
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:Apparently superior result was observed after open Kasai portoenterostomy in infant with biliary atresia. Our institute stopped performing laparoscopic portoenterostomy since 2007. We aimed to investigate the outcome after reintroduction of open portoenterostomy. METHODS:27 non-syndromic infants underwent open...
journal_title:Pediatric surgery international
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00