Abstract：
:Despite ongoing active research, the role of the radiation bystander effect in modifying local tissue response to an ionising radiation dose remains unclear. The present study aims to provide new insight by simulating the diffusion-mediated inter-cellular communication processes in 2D and 3D cell-like structures to calculate likely signal ranges in the diffusion limited case. Random walks of individual signalling molecules were tracked between cells with inclusion of molecule-receptor interactions. The resulting diffusion anomaly is a function of cell density, signal uptake probability and the spatial arrangement of cells local to the signal origin. Uptake probability effects dominate percolation effects in disordered media. Diffusion through 2D structures is more conducive to anomalous diffusion than diffusion through 3D structures. Values for time-dependent diffusion constants and permeability are derived for typical simulation parameters. Even at low signal uptake probabilities the communication range is restricted to a mean value of less than 100 μm owing to complete signal uptake by 600 s. This should be considered in light of the potential influence of signal relaying, flow-dynamics or vasculature-mediated signalling.
journal_name
Australas Phys Eng Sci Medjournal_title
Australasian physical & engineering sciences in medicineauthors
Moulton CR,Fleming AJ,Ebert MAdoi
10.1007/s13246-010-0048-ysubject
Has Abstractpub_date
2011-04-01 00:00:00pages
31-9issue
1eissn
0158-9938issn
1879-5447journal_volume
34pub_type
杂志文章abstract：:Lymphocyte recirculation between lymphatic and blood vessels and migration through tissues are essential mechanisms underlying immunological surveillance. However, the kinetics of lymphocyte migration through lymphoid tissues remains poorly understood. The present study of lymphocyte migration, based on a sheep model ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178774
更新日期：2002-09-01 00:00:00
abstract：:Bio-signal based assessment for upper-limb functions is an attractive technology for rehabilitation. In this work, an upper-limb function evaluator is developed based on biological signals, which could be used for selecting different robotic training protocols. Interaction force (IF) and participation level (PL, proce...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-019-00783-0
更新日期：2019-09-01 00:00:00
abstract：:The Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM) radiation oncology specialty group (ROSG) formed a series of working groups in 2011 to develop recommendations for guidance of radiation oncology medical physics practice within the Australasian setting. These recommendations are intend...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章,实务指引
doi：10.1007/s13246-015-0344-7
更新日期：2015-06-01 00:00:00
abstract：:This study was aimed to improve the surgical accuracy of plating and screwing for complicated tibial plateau fracture assisted by 3D implants library and 3D-printed navigational template. Clinical cases were performed whereby complicated tibial plateau fractures were imaged using computed tomography and reconstructed ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0330-0
更新日期：2015-03-01 00:00:00
abstract：:Post installation acceptance testing is vital to demonstrate that the equipment meets the vendor's specification and is suitable for clinical studies. The test procedures described in the NEMA NU 2-2001 document form the basis of vendor performance specifications of PET scanners and hence are also appropriate for acce...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-010-0016-6
更新日期：2010-06-01 00:00:00
abstract：:This paper presents a new method to apply timing characteristics of electroencephalograph (EEG) beta frequency bands to assess the depth of anaesthesia (DoA). Firstly, the measured EEG signals are denoised and decomposed into 20 different frequency bands. The Mobility (M), permutation entropy (PE) and Lempel-Ziv compl...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-016-0459-5
更新日期：2016-09-01 00:00:00
abstract：:Given that there is increasing recognition of the effect that sub-millimetre changes in collimator position can have on radiotherapy beam dosimetry, this study aimed to evaluate the potential variability in small field collimation that may exist between otherwise matched linacs. Field sizes and field output factors we...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0349-2
更新日期：2015-06-01 00:00:00
abstract：:Gravity associated with postural changes has a strong bearing on haemodynamics of blood flow in arteries. Its effect on stenosed cases has not been widely investigated. In the present study, variation observed in blood flow during postural changes is investigated for different conditions like standing, sleeping and he...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-014-0246-0
更新日期：2014-03-01 00:00:00
abstract：:In recent years, the use of gold nanoparticles in radiation therapy has been introduced as a new approach in radiotherapy. The aim of this study is to investigate the effect of gold nanoparticles (GNPs) in plaque brachytherapy for choroidal melanoma using Monte Carlo (MC) simulation. MCNPX code was used for simulation...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-017-0555-1
更新日期：2017-09-01 00:00:00
abstract：:A set of computer programs to simulate diagnostic x-ray spectra has been developed according to the method of Birch and Marshall, with good agreement to published HPA data. These programs have been extended to simulate spectra generated with capacitor discharge x-ray units. The application of these programs has proved...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:The quality of phantom materials is crucial for accurate dosimetry in radiotherapy. A wide range of factors such as density, electron density and elemental composition can influence the radiation properties, and hence the absorbed dose, of materials. New materials can be tested by direct measurements which requires co...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:The Resonant Recognition Model (rrm) uses digital signal processing methods to investigate protein structure-function; and links the biological function of protein families to unique characteristic frequencies. The rrm originally used a single set of variables: the electron ion interaction potential (EIIP). Here the r...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Two software packages designed for automatic counting nuclear tracks are tested and compared. The image processing in the first package is divided into three parts segmentation, speckle elimination and removal of ill-formed track holes. The second package is also divided into three parts but the last part is modified ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:This article outlines the enormous technological advances that have taken place in the practice of radiology in Australasia in the 30 years since approximately 1977. These developments have led to significant improvements in image quality across all modalities, including even general radiography, which had as its gene...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章,评审
doi：10.1007/BF03178423
更新日期：2007-09-01 00:00:00
abstract：:Laparoscopic ultrasound (LUS) has been widely utilized as a surgical aide in general, urological, and gynecological applications. Our study summarizes the clinical applications of laparoscopic ultrasonography in laparoscopic gynecologic surgery. Retrospective analyses were performed on 42 women subjects using laparosc...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0363-4
更新日期：2015-12-01 00:00:00
abstract：:A simple and rapid technique to measure the proton beam energy in the external beam line of a medical cyclotron has been examined. A stack of 0.1 mm thick high purity copper (Cu) foils was bombarded and the relative activity of 65Zn produced in each foil was compared to a computational model that predicted activity, b...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178634
更新日期：2009-06-01 00:00:00
abstract：:Monte Carlo modelling of particle transport problems in medical radiation physics offers significant advantages over other techniques. Experiments can be performed without having to set up the physical situation, and "impossible" experiments can be performed, such as labelling multiple-scattered particles or simulatin...
journal_title：Australasian physical & engineering sciences in medicine
pub_type：
doi：
更新日期：1990-09-01 00:00:00
abstract：:TomoTherapy can provide highly accurate SABR deliveries, but currently it does not have any effective motion management techniques. Shallow breathing has been identified as one possible motion management solution on TomoTherapy, which has been made possible with the BreatheWell audiovisual biofeedback (AVB) device. Si...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-019-00727-8
更新日期：2019-03-01 00:00:00
abstract：:Peripheral doses out of field could have short and long terms biological effects on patients treated with electron beams. In this study, peripheral dose outside the applicator was measured using the 6, 10 and 18 MeV beams of an Elekta synergy linac. For these beams dose profiles were measured using EBT3 film at variou...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-018-0660-9
更新日期：2018-09-01 00:00:00
abstract：:In this study, we assessed the accuracy of surface doses determined by direct measurement and treatment planning system (TPS) calculations, relative to benchmark Monte Carlo (MC) doses calculated at 70 μm for a 6 MV, 10 × 10 cm clinical radiotherapy beam. In a homogeneous phantom with both open and fixed wedged fields...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-012-0145-1
更新日期：2012-09-01 00:00:00
abstract：:The aim of this study was to determine whether there is an effect of mobile phone electromagnetic field emissions on the human electroencephalograph (EEG). EEG recordings from ten awake subjects were taken during exposure to radiofrequency (RF) emissions from a mobile phone positioned behind the head. Two experimental...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF03179176
更新日期：2003-12-01 00:00:00
abstract：:A set of four 4 MV photon beam compensators were produced, one for each field of a Hodgkins Disease treatment plan. The resultant dose profiles at various depths were measured by an ion chamber in water and by Kodak X-Omat V film in a Solid Water phantom, and compared to the doses calculated by a GE RT/Plan treatment ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:Rats are often used in the electromagnetic field (EMF) exposure experiments. In the study for the effect of 900 MHz EMF exposure on learning and memory in SD rats, the specific absorption rate (SAR) and the temperature rise in the rat head are numerically evaluated. The digital anatomical model of a SD rat is reconstr...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-013-0202-4
更新日期：2013-06-01 00:00:00
abstract：:The measurement of absorbed dose to water in a solid-phantom may require a conversion factor because it may not be radiologically equivalent to water. One phantom developed for the use of dosimetry is a solid water, RW3 white-polystyrene material by IBA. This has a lower mass-energy absorption coefficient than water d...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-011-0102-4
更新日期：2011-12-01 00:00:00
abstract：:The use of Speiser needles for interstitial implants has resulted in malfunctioning of HDR afterloading equipment due to seepage of blood. We have successfully used rounded ended needles in the patient after removal of the trocar ended needles, preventing the seepage of blood. This technique also helps to prevent any ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:The sample entropy (SampEn) has been widely used to quantify the complexity of RR-interval time series. It is a fact that higher complexity, and hence, entropy is associated with the RR-interval time series of healthy subjects. But, SampEn suffers from the disadvantage that it assigns higher entropy to the randomized ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-016-0457-7
更新日期：2016-09-01 00:00:00
abstract：:In recent years there has been a significant economic growth in South East Asia, along with it a concurrent development of medical physics. The status of four countries--Malaysia, Thailand, the Philippines and Indonesia are presented. Medical physicists in these countries have been experiencing the usual problems of l...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:The alcoholism can be detected by analyzing electroencephalogram (EEG) signals. However, analyzing multi-channel EEG signals is a challenging task, which often requires complicated calculations and long execution time. This paper proposes three data selection methods to extract representative data from the EEG signals...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0414-x
更新日期：2016-03-01 00:00:00
abstract：:Large differences in monitor units have been observed when RadCalc, a pencil-beam-algorithm based software, is used to verify clinical electron plans from Raystation, a Monte-Carlo-algorithm based planning system. To investigate the problem, a number of clinical plans as well as test plans were created and calculated ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-016-0470-x
更新日期：2016-09-01 00:00:00
abstract：:Fractal dimension has been proposed as a useful method for characterizing medical images. The fractal dimension is calculated from the average radial power spectrum of the image. However, simpler methods of calculation have been proposed. This paper examines a very simple and easily implemented method which has been p...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
