Investigating the impact of tumour motion on TomoTherapy stereotactic ablative body radiotherapy (SABR) deliveries on 3-dimensional and 4-dimensional computed tomography.

Abstract:

:TomoTherapy can provide highly accurate SABR deliveries, but currently it does not have any effective motion management techniques. Shallow breathing has been identified as one possible motion management solution on TomoTherapy, which has been made possible with the BreatheWell audiovisual biofeedback (AVB) device. Since both the shallow breathing technique and the clinical use of the BreatheWell device are novel, their implementation requires comprehensive verification and validation work. As the first stage of the validation, this paper investigates the impact of target motion on a TomoTherapy SABR delivery is assessed on both 3D CT and 4D CT using a 4D respiratory phantom. A dosimetric study on a 4D respiratory phantom was conducted, with the phantom's insert designed to move at four different amplitudes in the superior-inferior direction. SABR plans on 3D and 4D CT scans were created and measured. Critical plan statistics and measurement results were compared. It is found that for TomoTherapy SABR deliveries, by reducing the targets respiratory motion, target coverage, organ-at-risk (OAR) sparing, and delivery accuracy were improved.

authors

Hu Y,Archibald-Heeren B,Byrne M,Cai E,Wang Y

doi

10.1007/s13246-019-00727-8

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

169-179

issue

1

eissn

0158-9938

issn

1879-5447

pii

10.1007/s13246-019-00727-8

journal_volume

42

pub_type

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