Abstract：
:In general, a weighting factor of one is applied for low linear energy transfer radiations. However, several studies indicate that relative biological effectiveness (RBE) of low energy photons and electrons is greater than one. The aim of this current study was calculating the RBE of I-131 radiation relative to Co-60 gamma photons in 100 μm spheroid cells using Monte Carlo (MC) simulations. These calculations were compared to experimentally measured results. MCNPX2.6 was used to simulate the I-131 and Co-60 irradiation setups and calculate the secondary electron spectra at energies higher than 1 keV with varying oxygen concentrations. The electron spectra at energies lower than 1 keV were obtained by extrapolation (down to 10 eV). The calculated electron spectra were input into the MCDS micro-dosimetric Monte Carlo code to calculate the DSB induction and related RBE. The calculated RBE of I-131 radiation relative to Co-60 photons, as the reference radiation recommended by the International Commission on Radiation Protection (ICRP), was 1.06, 1.03 and 1.02 for oxygen concentrations of 0, 5 and 100%, respectively. Results of MC simulations indicate the RBE of I-131 is greater than one. This finding, despite a 10% discrepancy with the findings of the previous in vitro study of one of the authors of this paper, reemphasizes that I-131 radiation induces more severe biological damage than current ICRP recommendations.
journal_name
Australas Phys Eng Sci Medjournal_title
Australasian physical & engineering sciences in medicineauthors
Ezzati AO,Mahmoud-Pashazadeh A,Studenski MTdoi
10.1007/s13246-017-0544-4subject
Has Abstractpub_date
2017-06-01 00:00:00pages
395-400issue
2eissn
0158-9938issn
1879-5447pii
10.1007/s13246-017-0544-4journal_volume
40pub_type
杂志文章abstract：:A simple and rapid technique to measure the proton beam energy in the external beam line of a medical cyclotron has been examined. A stack of 0.1 mm thick high purity copper (Cu) foils was bombarded and the relative activity of 65Zn produced in each foil was compared to a computational model that predicted activity, b...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178634
更新日期：2009-06-01 00:00:00
abstract：:A set of computer programs to simulate diagnostic x-ray spectra has been developed according to the method of Birch and Marshall, with good agreement to published HPA data. These programs have been extended to simulate spectra generated with capacitor discharge x-ray units. The application of these programs has proved...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:Memory plays an important role in human life. Memory can be divided into two categories, i.e., long term memory and short term memory (STM). STM or working memory (WM) stores information for a short span of time and it is used for information manipulations and fast response activities. WM is generally involved in the ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章,评审
doi：10.1007/s13246-016-0438-x
更新日期：2016-06-01 00:00:00
abstract：:Diamond detectors are particularly well suited for dosimetry applications in radiotherapy for reasons including near-tissue equivalence and high-spatial resolution resulting from small sensitive volumes. However, these detectors have not become commonplace due to high cost and poor availability arising from the need f...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-010-0040-6
更新日期：2010-12-01 00:00:00
abstract：:The purpose of this paper is to describe an outline of a proton therapy system in Nagoya Proton Therapy Center (NPTC). The NPTC has a synchrotron with a linac injector and three treatment rooms: two rooms are equipped with a gantry and the other one is equipped with a fixed horizontal beamline. One gantry treatment ro...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-016-0456-8
更新日期：2016-09-01 00:00:00
abstract：:Radiation therapy of cancer is today going through a very dynamic development with the introduction of a large number of new treatment principles, new types of treatment units and new radiobiologically based optimization algorithms for treatment planning. All of these make use of the recent developments in three dimen...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：:Orthovoltage x-ray beams exhibit the characteristic of depth dose buildup which is not well described in the literature. The principal reason for this phenomenon is the increase in dose deposited due to electrons set in motion by secondary (Compton) scattered photons within the phantom, as depth is increased until lon...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Improved technology and higher fidelity are making medical simulations increasingly popular. A simulated peripheral nerve stimulator and thumb actuator has been developed for use with the SimMan Universal Patient Simulator. This device incorporates a handheld control box, a McKibben pneumatic muscle and articulated th...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-017-0555-1
更新日期：2017-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-011-0093-1
更新日期：2011-12-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-012-0145-1
更新日期：2012-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-012-0138-0
更新日期：2012-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0385-y
更新日期：2015-12-01 00:00:00
abstract：:Accelerator neutron sources for epithermal neutron capture therapy utilising the 7Li(p,n) nuclear reaction are proposed to operate in the range of 1.88 to 2.5 MeV proton energy. Operation with proton energies closer to the reaction threshold decreases neutron yield but allows for smaller reflector and moderator, with ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:Bipolar disorder (BD) is a severe psychiatric disorder and has two common types: type I and type II. Early diagnosis of the subtypes is very challenging particularly in adolescence. In this study, 38 adolescents are participated including 18 patients with BD I and 20 patients with BD II. The electroencephalogram signa...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0375-0
更新日期：2015-12-01 00:00:00
abstract：:In this paper, the peristaltic flow of rheologically complex physiological fluids when modelled by a non-Newtonian Casson fluid in a two-dimensional channel is considered. Of interest is the difference between peristaltic transport of Newtonian and non-Newtonian fluids. A perturbation series method of solution of the ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Rotary blood pumps have the potential to become a viable long-term treatment option for the heart failure patients to bridge to transplantation or destination therapy. However, these devices operate at a constant speed which may lead to long term complications or they may operate in an undesired support mode such as e...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章,评审
doi：10.1007/s13246-015-0405-y
更新日期：2016-03-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178704
更新日期：2005-06-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type：
doi：
更新日期：1990-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0362-5
更新日期：2015-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178670
更新日期：2004-09-01 00:00:00
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journal_title：Australasian physical & engineering sciences in medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF03179176
更新日期：2003-12-01 00:00:00
abstract：:Bicoherence analysis is applied to electromyogram (EMG) data for the vastus lateralis quadriceps muscle of 18 adult male subjects for isometric knee extension exercise. Bicoherence spectra display ridge-like features that are indicative of deterministic chaotic behaviour and similar to those reported for normal electr...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF03178691
更新日期：2003-03-01 00:00:00
abstract：:The reference air kerma rate from 192Ir High Dose Rate (HDR) brachytherapy sources can be measured using a suitably calibrated Farmer chamber and an appropriate in-air calibration jig. When a primary standard for 192Ir gamma rays is available, a calibration coefficient for the chamber and jig combination can be determ...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178603
更新日期：2008-12-01 00:00:00
abstract：:Despite ongoing active research, the role of the radiation bystander effect in modifying local tissue response to an ionising radiation dose remains unclear. The present study aims to provide new insight by simulating the diffusion-mediated inter-cellular communication processes in 2D and 3D cell-like structures to ca...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-010-0048-y
更新日期：2011-04-01 00:00:00
abstract：:Surface, build-up and depth dose characteristics of a monoenergetic electron point source simulated by Monte Carlo code MCNP4c for varying field size and SSD are extensively studied in this paper. MCNP4c (Monte Carlo N-Particle Transport Code System) has been extensively used in clinical dose simulation for its versat...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/BF03178652
更新日期：2004-12-01 00:00:00
abstract：:It was the aim of this work to assess and track the workload, working conditions and professional recognition of radiation oncology medical physicists (ROMPs) in the Asia Pacific region over time. In this third survey since 2008, a structured questionnaire was mailed in 2014 to 22 senior medical physicists representin...
journal_title：Australasian physical & engineering sciences in medicine
pub_type： 杂志文章
doi：10.1007/s13246-015-0373-2
更新日期：2015-09-01 00:00:00
