Abstract：
:Lymphocyte recirculation between lymphatic and blood vessels and migration through tissues are essential mechanisms underlying immunological surveillance. However, the kinetics of lymphocyte migration through lymphoid tissues remains poorly understood. The present study of lymphocyte migration, based on a sheep model and entailing the long term cannulation of blood vessels and lymphatic vessels efferent from lymph nodes, represents the first attempt to apply control engineering based models to overcome some of the experimental impediments to understanding the complex phenomena involved in lymphocyte migration. An output error model order (1,2,nk) was systematically selected under given criteria from four classes of Linear Time-Invariant Single-Input Single-Output, (LTI-SISO) systems to represent the peripheral lymph node system. The unit impulse responses were simulated under noise free conditions and their features were extracted to describe the dynamics of the system. The findings from this study revealed novel information about several aspects of the dynamics of lymphocyte migration.
journal_name
Australas Phys Eng Sci Medjournal_title
Australasian physical & engineering sciences in medicineauthors
Srikusalanukul W,De Bruyne F,McCullagh Pdoi
10.1007/BF03178774subject
Has Abstractpub_date
2002-09-01 00:00:00pages
132-8issue
3eissn
0158-9938issn
1879-5447journal_volume
25pub_type
杂志文章abstract：:This article outlines the enormous technological advances that have taken place in the practice of radiology in Australasia in the 30 years since approximately 1977. These developments have led to significant improvements in image quality across all modalities, including even general radiography, which had as its gene...
journal_title：Australasian physical & engineering sciences in medicine
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journal_title：Australasian physical & engineering sciences in medicine
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journal_title：Australasian physical & engineering sciences in medicine
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