Hepatitis C virus genotype 4 with normal transaminases: histological changes, schistosomiasis and response to treatment.

abstract：:This study estimated latent classes (ie, unobserved subgroups in a population) of people who use drugs in Vancouver, Canada, and examined how these classes relate to phylogenetic clustering of hepatitis C virus (HCV) infection. HCV antibody-positive people who use drugs from two cohorts in Vancouver, Canada (1996-2012...

journal_title：Journal of viral hepatitis

authors： Jacka B,Bray BC,Applegate TL,Marshall BDL,Lima VD,Hayashi K,DeBeck K,Raghwani J,Harrigan PR,Krajden M,Montaner JSG,Grebely J Senior

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to assess the efficacy and safety of two protocols for retreatment of a cohort of Egyptian patients with chronic hepatitis C (CHC) who relapsed after NS5A inhibitor-based therapy. We conducted a prospective cohort study to assess the safety and efficacy of 12 weeks' retreatment with either co...

journal_title：Journal of viral hepatitis

authors： Yousif MM,Ahmed H,Elsadek HM,Shendi AM,Gouda TM,Elsayed IA,Gendia MA,Magdy MM,Lbrahim NF,Sadek AMEM,Zaki AM,Shafeik H,Zahran MH

更新日期：2020-11-01 00:00:00

abstract：:This study assessed the association of HIV RNA with indirect markers of liver injury including FIB-4 index, liver enzymes and platelet counts in a high-risk Hispanic population. The data were derived from a prospective study that included 138 HIV/hepatitis C (HCV)-coinfected and 68 HIV-infected participants without he...

journal_title：Journal of viral hepatitis

authors： Forrester JE,Rhee MS,McGovern BH,Sterling RK,Knox TA,Terrin N

更新日期：2012-02-01 00:00:00

abstract：:Infection with the hepatitis C virus (HCV) remains chronic in 75% of infected individuals, in whom it can cause liver inflammation and progressive fibrosis leading to cirrhosis in 20% of patients. A sustained viral response (SVR) to HCV therapy, i.e. undetectable plasma HCV RNA 6 months after the end of treatment, lea...

journal_title：Journal of viral hepatitis

authors： Bräu N

更新日期：2004-05-01 00:00:00

abstract：:Self-efficacy or confidence in one's ability to successfully engage in goal-directed behaviour has been shown to influence medication adherence across many chronic illnesses. In the present study, we investigated the psychometric properties of a self-efficacy instrument used during treatment for chronic hepatitis C vi...

journal_title：Journal of viral hepatitis

authors： Bonner JE,Esserman D,Evon DM

更新日期：2012-05-01 00:00:00

abstract：:The aim of this study was to assess the validity of categorization of chronic hepatitis B viral infection into stages or phases based upon measures of disease activity and viral load, assuming these phenotypes will be useful for prognostication and determining the need for antiviral therapy. We assessed the phenotype ...

journal_title：Journal of viral hepatitis

authors： Di Bisceglie AM,Lombardero M,Teckman J,Roberts L,Janssen HL,Belle SH,Hoofnagle JH,Hepatitis B Research Network (HBRN).

更新日期：2017-04-01 00:00:00

abstract：:Better convenience and tolerability and sustained therapeutic concentrations might improve interferon (IFN) treatment for chronic hepatitis C virus (HCV) infection. In an open-label, randomized study, controlled release free (chemically unmodified) recombinant human IFN-α(2b) in poly(ether-ester) microspheres (CR-rhIF...

journal_title：Journal of viral hepatitis

authors： Dzyublyk I,Yegorova T,Moroz L,Popovych O,Zaytsev I,Miroshnichenko V,Kromminga A,Wilkes MM,van Hoogdalem EJ,Humphries JE

更新日期：2011-04-01 00:00:00

abstract：:The World Health Organization has set the goal of reducing the hepatitis-related mortality rate by 65% between 2015 and 2030. Diagnosis and awareness of infection is the first essential step towards achieving this goal. Our study examined the current awareness rate of chronic viral hepatitis in the United States and t...

journal_title：Journal of viral hepatitis

authors： Kim HS,Yang JD,El-Serag HB,Kanwal F

更新日期：2019-05-01 00:00:00

abstract：:Reports have described a decrease in glomerular filtration rate (eGFR) associated with tenofovir disoproxil fumarate (TDF) use in HIV positive individuals. However, no study has examined renal function over a prolonged period in HIV/hepatitis B virus (HBV) co-infected patients. We assessed the long-term durability and...

journal_title：Journal of viral hepatitis

authors： Tan LK,Gilleece Y,Mandalia S,Murungi A,Grover D,Fisher M,Atkins M,Nelson M

更新日期：2009-07-01 00:00:00

abstract：:Travel to endemic areas is one of the most frequently reported risk factors for infection with the hepatitis A virus (HAV). We evaluated the association between HAV infection and travel, by area of destination. We conducted a case-control study on all cases of HAV infection reported to the Italian National Surveillanc...

journal_title：Journal of viral hepatitis

authors： Ciccozzi M,Tosti ME,Gallo G,Ragni P,Zotti C,Lopalco P,Ara G,Sangalli M,Balocchini E,Szklo AS,Mele A,SEIEVA collaborating group.

更新日期：2002-11-01 00:00:00

abstract：:High rates (~25%) of developing chronic hepatitis B virus (HBV) infection (hepatitis B surface antigen (HBsAg)-positive for > 6 months following infection) have been observed in people who use drugs (PWUD) and men who have sex with men (MSM). We aimed to estimate the frequency of delayed HBsAg seroclearance, along wit...

journal_title：Journal of viral hepatitis

authors： van Santen DK,Boyd A,Bruisten S,Sonder GJ,Prins M,van Houdt R

更新日期：2020-01-01 00:00:00

abstract：:Despite the availability of effective therapy for hepatitis C virus (HCV) infection, there are little data on the uptake of treatment. We evaluated factors associated with HCV infection and the uptake of HCV treatment in a large community-based inner city cohort in Vancouver, Canada. The Community Health and Safety Ev...

journal_title：Journal of viral hepatitis

authors： Grebely J,Raffa JD,Lai C,Krajden M,Kerr T,Fischer B,Tyndall MW

更新日期：2009-05-01 00:00:00

abstract：:In patients with chronic hepatitis B (CHB), long-term effects of tenofovir disoproxil fumarate (TDF) on renal function have been controversial. This study aimed to analyse the real-world long-term effects of TDF on renal function in Korean patients with CHB. We analysed a cohort of 640 treatment-naïve patients with CH...

journal_title：Journal of viral hepatitis

authors： Lim TS,Lee JS,Kim BK,Lee HW,Jeon MY,Kim SU,Park JY,Kim DY,Han KH,Ahn SH

更新日期：2020-03-01 00:00:00

abstract：:Children with chronic hepatitis C may be ideal candidates for treatment with interferon alpha (IFNalpha) as they have liver disease at an early stage. However, adverse drug reactions need to be considered. The aim of this study was to conduct a systematic review of literature on interferon therapy of chronic hepatitis...

journal_title：Journal of viral hepatitis

authors： Di Ciommo V,Russo P,Ravà L,Caprino L

更新日期：2003-05-01 00:00:00

abstract：:Hepatitis B virus surface antigen (HBsAg) plays an important role in maintaining the tolerance and may interfere with host innate and adaptive immune responses; therefore, novel therapeutic strategies to reduce HBsAg loads in patients infected with hepatitis B virus (HBV) are emerging as an attractive but challenging ...

journal_title：Journal of viral hepatitis

authors： Xun YH,Zhang YJ,Pan QC,Mao RC,Qin YL,Liu HY,Zhang YM,Yu YS,Tang ZH,Lu MJ,Zang GQ,Zhang JM

更新日期：2014-08-01 00:00:00

abstract：:The establishment of an in vitro system for hepatitis C virus (HCV) propagation is essential to characterize virus replication, virus persistence and viral pathogenicity. The aim was to establish HCV replication in HepG2 cells by gene transfer of infectious HCV cDNA. First, several gene transfer methods were evaluated...

journal_title：Journal of viral hepatitis

authors： Hiramatsu N,Dash S,Gerber MA

更新日期：1997-01-01 00:00:00

abstract：:Interferon-alpha 2b (IFN-alpha 2b) can exert antiproliferative activity in both normal and malignant liver tissue. To study mechanisms of its antiproliferative action, the activity of the enzymes of adenosine metabolism were investigated. We studied 5'-nucleotidase (an adenosine-producing enzyme) and adenosine deamina...

journal_title：Journal of viral hepatitis

authors： Kocić G,Kocić R,Vlahović P,Pavlović D,Jevtović T

更新日期：1998-09-01 00:00:00

abstract：:The efficacy and tolerability of 12-month treatment with titrated doses of recombinant interferon-alpha 2a (IFN-alpha 2a) in chronic hepatitis C were studied in 67 consecutively recruited patients randomly assigned either to a starting dose of IFN-alpha 2a 6 MU, subsequently adjusted to the serum alanine aminotransfer...

journal_title：Journal of viral hepatitis

authors： Rumi MG,del Ninno E,Parravicini ML,Romeo R,Soffredini R,Donato MF,Zahm F,Colombo M

更新日期：1995-01-01 00:00:00

abstract：:Hepatitis E virus (HEV) represents one of the foremost causes of acute hepatitis globally. Although there is no proven medication for hepatitis E, pegylated interferon-α (IFN-α) has been used as off-label drug for treating HEV. However, the efficacy and molecular mechanisms of how IFN signalling interacts with HEV rem...

journal_title：Journal of viral hepatitis

authors： Zhou X,Xu L,Wang W,Watashi K,Wang Y,Sprengers D,de Ruiter PE,van der Laan LJ,Metselaar HJ,Kamar N,Peppelenbosch MP,Pan Q

更新日期：2016-04-01 00:00:00

abstract：:There are few extant studies on the prevalence of HBV infection in couples preparing for pregnancy. We assessed the prevalence of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) in couples preparing for pregnancy in rural China, and the association between HBV prevalence and the statuses of HBsAg...

journal_title：Journal of viral hepatitis

authors： Liu J,Zhang S,Wang Q,Shen H,Zhang M,Zhang Y,Yan D,Liu M

更新日期：2017-08-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication in patients with decompensated cirrhosis and is also an important cause for poor outcome. This study aimed at investigating the clinical characteristics and long-term prognosis of AKI in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACL...

journal_title：Journal of viral hepatitis

authors： Shi X,Zhu P,Yan G,Liu C,Zhang C,Huang G,Zhang Y,Yan Z,Wang Y

更新日期：2016-11-01 00:00:00

abstract：:The pathogenesis of liver damage in the course of hepatitis B virus (HBV) infection depends on the host's specific and non-specific immune response to various viral antigens. The role of polymorphonuclear neutrophils (PMN) in the natural immune reaction and during secondary microbial infections is well documented. Inc...

journal_title：Journal of viral hepatitis

authors： Sułowska Z,Pietruszynski R,Dworniak D,Tchórzewski H,Sidorkiewicz M

更新日期：1996-11-01 00:00:00

abstract：:Viral load reduction facilitates recovery of antiviral T-cell responses. Dynamic alterations in intrahepatic viraemia clearance and immune cell reactivity during the early phase of nucleoside analogue (NA) therapy and the impact of these changes on HBeAg seroconversion are unknown. Fifteen HBeAg-positive chronic hepat...

journal_title：Journal of viral hepatitis

authors： Zheng Q,Zhu YY,Chen J,Liu YR,You J,Dong J,Zeng DW,Gao LY,Chen LH,Jiang JJ

更新日期：2014-12-01 00:00:00

abstract：:Dendritic cells (DCs) in chronic hepatitis C patients display impaired function, although the details remain unclear. To investigate the hepatitis C virus (HCV) protein that has the most impact on DC function, we compared five recombinant proteins and seven HCV protein genes in modulating DC phenotype and function. Im...

journal_title：Journal of viral hepatitis

authors： Takaki A,Tatsukawa M,Iwasaki Y,Koike K,Noguchi Y,Shiraha H,Sakaguchi K,Nakayama E,Yamamoto K

更新日期：2010-08-01 00:00:00

abstract：:We systematically reviewed the evidence for long-term effectiveness and cost-effectiveness of antiviral treatment in patients with chronic hepatitis C. We performed a systematic literature search on the long-term effectiveness and cost-effectiveness of AVT in hepatitis C (1990-March 2007), and included health technolo...

journal_title：Journal of viral hepatitis

authors： Sroczynski G,Esteban E,Conrads-Frank A,Schwarzer R,Mühlberger N,Wright D,Zeuzem S,Siebert U

更新日期：2010-01-01 00:00:00

abstract：:Patients with chronic hepatitis B (HBsAg-positive) are at risk of viral reactivation if rituximab is administered without antiviral treatment, a potentially fatal complication of treatment. Patients with so-called 'resolved hepatitis B virus infection' (HBsAg-negative/cAb-positive) may also be at risk. We performed a ...

journal_title：Journal of viral hepatitis

authors： Mozessohn L,Chan KK,Feld JJ,Hicks LK

更新日期：2015-10-01 00:00:00

abstract：:Women with chronic hepatitis B should maintain nucleotide analogue treatment to prevent disease progression during pregnancy. The aim of this study was to prospectively evaluate the efficacy and safety of telbivudine used throughout pregnancy for preventing hepatitis B virus (HBV) mother-to-child transmission (MTCT). ...

journal_title：Journal of viral hepatitis

authors： Yi W,Li MH,Xie Y,Wu J,Hu YH,Zhang D,Zhang Y,Cao WH

更新日期：2017-11-01 00:00:00

abstract：:People who use drugs are a key population in global HCV control. We evaluated the efficacy of an innovative model to eliminate HCV infection in a high-risk population of PWUD in a service for substance use disorder (SUD). Between January 2018 and December 2018, we conducted a prospective, interventional, before and af...

journal_title：Journal of viral hepatitis

authors： Messina V,Russo A,Parente E,Russo G,Raimondo T,Salzillo A,Simeone F,Onorato L,Di Caprio G,Pisaturo M,Coppola N

更新日期：2020-12-01 00:00:00

abstract：:The potential interaction between chronic hepatitis B (CHB) and nonalcoholic fatty liver disease (NAFLD), two of the most prevalent liver diseases worldwide, has not been well defined. We performed liver stiffness (LS) and controlled attenuation parameter (CAP) measurements using transient elastography in 1202 CHB pat...

journal_title：Journal of viral hepatitis

authors： Hui RWH,Seto WK,Cheung KS,Mak LY,Liu KSH,Fung J,Wong DK,Lai CL,Yuen MF

更新日期：2018-01-01 00:00:00

abstract：:Italy is one of the countries on track with the WHO's agenda to eliminate hepatitis C virus (HCV) by 2030. Healthcare facilities play a crucial role in seeking patients who are infected but have not yet been treated. We assessed the effectiveness of a recall strategy, named 'Telepass' project, for patients exposed to ...

journal_title：Journal of viral hepatitis

authors： Ponziani FR,Santopaolo F,Siciliano M,De Belvis AG,Tortora A,Mora V,Fanali C,Morsella A,Balducci F,Vetrugno G,D'Alfonso ME,Cambieri A,Cauda R,Bellantone R,Sanguinetti M,Pompili M,Gasbarrini A

更新日期：2021-01-09 00:00:00