Reliability and validity of a self-efficacy instrument for hepatitis C antiviral treatment regimens.

abstract：:Although tattooing is recognized as a risk factor for transmission of hepatitis C, the efficiency with which transmission occurs is unknown. Sera stored from a serosurvey of tattooists undertaken in 1984 to test for human immunodeficiency virus (HIV) provided the opportunity to determine the prevalence of serological ...

journal_title：Journal of viral hepatitis

authors： Thompson SC,Goudey RE,Breschkin AM,Carnie J,Catton M

更新日期：1997-03-01 00:00:00

abstract：:Sustained virologic response (SVR) is the standard measure for evaluating response to therapy in patients with chronic hepatitis C (CHC). The aim of this study was to prospectively assess the durability of SVR in the pivotal studies of peginterferon (PEG-IFN) α-2b or IFN α-2b. We conducted two phase 3b long-term follo...

journal_title：Journal of viral hepatitis

authors： Manns MP,Pockros PJ,Norkrans G,Smith CI,Morgan TR,Häussinger D,Shiffman ML,Hadziyannis SJ,Schmidt WN,Jacobson IM,Bárcena R,Schiff ER,Shaikh OS,Bacon B,Marcellin P,Deng W,Esteban-Mur R,Poynard T,Pedicone LD,Brass CA

更新日期：2013-08-01 00:00:00

abstract：:The impact of direct-acting antiviral (DAA) therapies on fibrosis regression remains uncertain. In the current study, we prospectively evaluated dynamics of liver stiffness by transient elastography (TE) in patients with chronic HCV infection receiving DAA-based treatment. Patients (260) were enrolled in the German He...

journal_title：Journal of viral hepatitis

authors： Knop V,Mauss S,Goeser T,Geier A,Zimmermann T,Herzer K,Postel N,Friedrich-Rust M,Hofmann WP,German Hepatitis C-Registry.

更新日期：2020-07-01 00:00:00

abstract：:Only in a minority of patients with chronic hepatitis B (CHB) will treatment with interferon (IFN)-alpha or nucleoside analogues lead to sustained virological response. In vivo immunization (IVI) following virus suppression aims to optimize conditions for an effective immune response: following rapid and profound viru...

journal_title：Journal of viral hepatitis

authors： Sprengers D,van der Molen RG,Binda R,Kusters JG,de Man RA,Niesters HG,Schalm SW,Janssen HL

更新日期：2007-10-01 00:00:00

abstract：:A simple, pangenotypic and effective treatment regimen for patients with a broad range of chronic hepatitis C virus (HCV) infections remains an unmet medical need. We conducted a phase 2, randomized, open study involving untreated patients with chronic HCV genotypes 1, 2, 3, or 6 infections. Patients without cirrhosis...

journal_title：Journal of viral hepatitis

authors： Rao H,Song G,Li G,Yang Y,Wu X,Guan Y,Mao Q,Jiang X,Wang C,Zhang Y,Jia J,Guo X,Li C,Ning J,Qin H,Pan H,Wei L

更新日期：2020-01-01 00:00:00

abstract：:Although hepatitis C (HCV) is associated with diabetes, few studies have examined pre-diabetes in this population. We aimed to evaluate factors associated with pre-diabetes in HCV-infected patients, including direct measurement of insulin action. Ninety-seven non-cirrhotic, non-diabetic and HCV-infected patients under...

journal_title：Journal of viral hepatitis

authors： Mukhtar NA,Ayala C,Maher JJ,Khalili M

更新日期：2012-07-01 00:00:00

abstract：:Serological and biochemical studies indicate that acute HBV infection is resolved in the context of an efficient cell-mediated immune (CMI) response, whereas, chronic infection is characterized by weak to undetectable CMI responses and relatively efficient humoral immunity. Because humoral immunity and CMI are regulat...

journal_title：Journal of viral hepatitis

authors： Milich DR

更新日期：1997-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) and hepatitis B virus (HBV) frequently coinfect and persist long after clinical resolution. We assessed the incidence of low-level (occult) HCV infection (OCI) after sustained virological response (SVR) to standard anti-HCV therapy in individuals with or without past exposure to HBV to recogniz...

journal_title：Journal of viral hepatitis

authors： Pham TN,Coffin CS,Churchill ND,Urbanski SJ,Lee SS,Michalak TI

更新日期：2012-02-01 00:00:00

abstract：:Chronic hepatitis C virus (HCV) infection leads to mixed cryoglobulinaemia (MC) and B-cell non-Hodgkin lymphoma (B-NHL). Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 is associated with lymphomagenesis. Recently, HCV was shown to induce BCL-6 mutations in vitro. The BCL-6 gene (area B) was clon...

journal_title：Journal of viral hepatitis

authors： Hofmann WP,Fernandez B,Herrmann E,Welsch C,Mihm U,Kronenberger B,Feldmann G,Spengler U,Zeuzem S,Sarrazin C

更新日期：2007-07-01 00:00:00

abstract：:Drug users with chronic hepatitis C virus (HCV) infection are frequently co-infected with human immunodeficiency virus-1 (HIV-1), but it is still not clear whether HIV-1 worsens the natural history of hepatitis C. To investigate this, we conducted a multicentre observational study in 163 drug addicts with histological...

journal_title：Journal of viral hepatitis

authors： Romeo R,Rumi MG,Donato MF,Cargnel MA,Viganò P,Mondelli M,Cesana B,Colombo M

更新日期：2000-07-01 00:00:00

abstract：:Significant advances have been made, during the last 5 years, in the treatment of chronic hepatitis B. Several new antiviral agents: lamivudine, famciclovir, lobucavir and adefovir, have been shown to be safe and effective in inhibiting hepatitis B virus (HBV) replication. These compounds can be administered orally an...

journal_title：Journal of viral hepatitis

authors： Hussain M,Lok AS

更新日期：1999-05-01 00:00:00

abstract：:Transient elastography (TE) is the reference method to obtain liver stiffness measurements (LSM), but no results are obtained in 3.1% and unreliable in 15.8%. We assessed the applicability and diagnostic accuracy of TE re-evaluation using M and XL probes. From March 2011 to April 2012 868 LSM were performed with the M...

journal_title：Journal of viral hepatitis

authors： Carrión JA,Puigvehí M,Coll S,Garcia-Retortillo M,Cañete N,Fernández R,Márquez C,Giménez MD,Garcia M,Bory F,Solà R

更新日期：2015-03-01 00:00:00

abstract：:The relationship between hepatitis B virus (HBV) gene polymorphism and intrauterine infection has not been completely illuminated. Six pairs of mother and infant from intrauterine infection group and six mothers from nonintrauterine infection group in the previous study were randomly selected and separately divided in...

journal_title：Journal of viral hepatitis

authors： Wang LJ,Xu YF,Liu XX,Chen Y

更新日期：2015-04-01 00:00:00

abstract：:The non-structural (NS)5A protein of hepatitis C virus (HCV) is cleaved, after translation, by the NS3-encoded zinc-dependent serine proteinase, from the NS4B protein upstream and the NS5B protein downstream. The released, mature NS5A protein is a 56 000 MW phosphoprotein (p56), which also exists within infected cells...

journal_title：Journal of viral hepatitis

authors： Pawlotsky JM,Germanidis G

更新日期：1999-09-01 00:00:00

abstract：:The objective of this study was to analyse data related to hospitalization, comorbidities, average stays and costs associated with the hospitalization cases of hepatitis A in Spain, during the period between 2000 and 2005. A retrospective, descriptive study of the epidemiological characteristics of hepatitis A patient...

journal_title：Journal of viral hepatitis

authors： Arteaga A,Carrasco-Garrido P,de Andres AL,de Miguel AG,Jiménez-García R

更新日期：2009-04-01 00:00:00

abstract：:To determine the relationship between p53 altered expression and p53 mutations in hepatocellular carcinoma (HCC), we analysed p53 protein immunohistochemically and assessed the presence of mutations in exons 4-8 of the p53 gene using SSCP assay in 117 HCCs corresponding to 78 patients. We also determined the relations...

journal_title：Journal of viral hepatitis

authors： Anzola M,Saiz A,Cuevas N,Lopez-Martinez M,Martinez de Pancorbo MA,Burgos JJ

更新日期：2004-11-01 00:00:00

abstract：:Very little is known about the interactions between hepatitis C virus (HCV) and methamphetamine, which is a highly abused psychostimulant and a known risk factor for human immunodeficiency virus (HIV)/HCV infection. This study examined whether methamphetamine has the ability to inhibit innate immunity in the host cell...

journal_title：Journal of viral hepatitis

authors： Ye L,Peng JS,Wang X,Wang YJ,Luo GX,Ho WZ

更新日期：2008-04-01 00:00:00

abstract：:Many patients chronically infected by hepatitis C virus (HCV) experience symptoms like fatigue, dyspnea and reduced physical activity. However, in many patients, these symptoms are not proportional to the liver involvement and could resemble symptoms of chronic heart failure. To our knowledge, no study evaluated serum...

journal_title：Journal of viral hepatitis

authors： Antonelli A,Ferri C,Ferrari SM,Colaci M,Sebastiani M,Zignego AL,Ghiri E,Goglia F,Fallahi P

更新日期：2010-12-01 00:00:00

abstract：:To investigate the long-term prognosis of liver disease in patients with hepatitis C virus (HCV) eradication after antiviral therapy versus those with persistent HCV infection. Four hundred and eighty patients (5259 person-years [PYs]) who received interferon-based therapy and achieved sustained virologic response and...

journal_title：Journal of viral hepatitis

authors： Tada T,Toyoda H,Kumada T,Kurisu A,Sugiyama A,Akita T,Ohisa M,Aikata H,Miki D,Chayama K,Tanaka J

更新日期：2020-11-20 00:00:00

abstract：:Treating chronic hepatitis C with pegylated interferon alpha may induce or exacerbate psychiatric illness including depression, mania and aggressive behaviour. There is limited data regarding treatment in the context of chronic schizophrenia. We sought to establish the safety and efficacy of treating patients with sch...

journal_title：Journal of viral hepatitis

authors： Mustafa MZ,Schofield J,Mills PR,Priest M,Fox R,Datta S,Morris J,Forrest EH,Gillespie R,Stanley AJ,Barclay ST

更新日期：2014-07-01 00:00:00

abstract：:Cognitive impairment occurs in 30%-50% of patients with non-cirrhotic chronic hepatitis C virus (HCV) infection. Exercise is beneficial in preventing and treating cognitive impairment and cardiometabolic abnormalities in many chronic inflammatory diseases, but there are few studies investigating the impact of exercise...

journal_title：Journal of viral hepatitis

authors： O'Gorman P,Strahan O,Ferguson D,Monaghan A,Kennedy M,Forde C,Melo AM,Doherty DG,O'Brien KK,McKiernan S,Kenny RA,Coen R,Doherty C,Bergin C,Gormley J,Norris S

更新日期：2020-12-28 00:00:00

abstract：:Hepatitis B virus (HBV) infection is considered a major health problem in the world. HBV is classified into genotypes A to J disseminated worldwide. Genotypes A, D and F are the most frequent in the Western World, B and C are predominant in the East, and E, F, H and J are infrequent and restricted to specific regions....

journal_title：Journal of viral hepatitis

authors： Wolf JM,De Carli S,Pereira VRZB,Simon D,Lunge VR

更新日期：2021-02-01 00:00:00

abstract：:Herpes simplex virus (HSV) hepatitis is a rare and potential life-threatening disease. The diagnosis of HSV hepatitis is hampered by its indifferent clinical presentation, which necessitates confirmatory laboratory data to identify HSV in the affected liver. However, liver biopsies are often contraindicated in the con...

journal_title：Journal of viral hepatitis

authors： Beersma MF,Verjans GM,Metselaar HJ,Osterhaus AD,Berrington WR,van Doornum GJ

更新日期：2011-04-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication in patients with decompensated cirrhosis and is also an important cause for poor outcome. This study aimed at investigating the clinical characteristics and long-term prognosis of AKI in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACL...

journal_title：Journal of viral hepatitis

authors： Shi X,Zhu P,Yan G,Liu C,Zhang C,Huang G,Zhang Y,Yan Z,Wang Y

更新日期：2016-11-01 00:00:00

abstract：:Hepatitis B e antigen (HBeAg)-negative infections are an unusual form of chronic hepatitis B virus (HBV) infection in which viral replication and liver damage persist despite antibodies against HBeAg. This form of HBV may be associated with fulminant hepatitis. The molecular basis for an HBeAg-minus phenotype has been...

journal_title：Journal of viral hepatitis

authors： Miyakawa Y,Okamoto H,Mayumi M

更新日期：1997-01-01 00:00:00

abstract：:The study aimed to assess whether caesarean section and nonbreastfeeding can prevent mother-to-child transmission (MTCT) in HBsAg- and HBeAg-positive mothers via a cohort study and a meta-analysis. (1) Pregnant women who were positive for HBsAg and HBeAg and did not receive antiviral treatment during pregnancy were re...

journal_title：Journal of viral hepatitis

authors： Pan YC,Jia ZF,Wang YQ,Yang N,Liu JX,Zhai XJ,Song Y,Wang C,Li J,Jiang J

更新日期：2020-10-01 00:00:00

abstract：:Hepatitis C (HCV) infection can cause cirrhosis, liver cancer and death in the absence of treatment. Many people living in the UK but born overseas are believed to be infected with HCV although many are unlikely to know they are infected. The aim of this study is to assess the potential for a case-finding approach to ...

journal_title：Journal of viral hepatitis

authors： Miners AH,Martin NK,Ghosh A,Hickman M,Vickerman P

更新日期：2014-01-01 00:00:00

abstract：:Approximately 5% of the healthy adult population respond inadequately to the commercial recombinant hepatitis B vaccines. As the recombinant vaccines all have an aluminium-based adjuvant, we tried to enhance the immune response by adding a cytokine-based adjuvant. This new adjuvant AI20, containing 20 μg recombinant h...

journal_title：Journal of viral hepatitis

authors： Koc ÖM,Savelkoul PHM,van Loo IHM,Peeters A,Oude Lashof AML

更新日期：2018-09-01 00:00:00

abstract：:In patients with chronic hepatitis B (CHB), long-term effects of tenofovir disoproxil fumarate (TDF) on renal function have been controversial. This study aimed to analyse the real-world long-term effects of TDF on renal function in Korean patients with CHB. We analysed a cohort of 640 treatment-naïve patients with CH...

journal_title：Journal of viral hepatitis

authors： Lim TS,Lee JS,Kim BK,Lee HW,Jeon MY,Kim SU,Park JY,Kim DY,Han KH,Ahn SH

更新日期：2020-03-01 00:00:00

abstract：:The triglycerides × glucose (TyG) index is a recently proposed surrogate marker of insulin resistance (IR), calculated from fasting plasma triglyceride and glucose concentrations. We tested the host and viral factors associated with Tyg and homeostasis model assessment (HOMA) scores, comparing their associations with ...

journal_title：Journal of viral hepatitis

authors： Petta S,Di Marco V,Di Stefano R,Cabibi D,Cammà C,Marchesini G,Craxì A

更新日期：2011-07-01 00:00:00