Risk of hepatitis A infection following travel.

abstract：:There is little data on the long-term follow-up outcomes of chronic hepatitis C patients achieving sustained virological response (SVR) after treatment with peglylated interferon-α plus ribavirin. We prospectively investigated the overall clinical, biochemical, virological and histological outcomes in a ten-year cohor...

journal_title：Journal of viral hepatitis

authors： Wang X,Gao F,Yuan G,Shi K,Huang Y,Chen Y,Qiu R,Sun L,Liu J,Hu C,Zhou Y

更新日期：2016-12-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection induces a wide range of chronic liver injury. The mechanism by which HBV evades the immune surveillance system remains obscure. Plasmacytoid dendritic cells (pDCs) seem to be the major endogenous interferon (IFN)-alpha producers and represent one of the most important cell types in th...

journal_title：Journal of viral hepatitis

authors： Wang K,Fan X,Fan Y,Wang B,Han L,Hou Y

更新日期：2007-04-01 00:00:00

abstract：:In previous hepatitis C virus (HCV) treatment studies, Black patients not only had a lower sustained viral response (SVR) rate to interferon and ribavirin (RBV) than non-Black patients but also a higher frequency of HCV genotype 1 (GT-1) infection. The aim of this community-based study was to determine whether Black p...

journal_title：Journal of viral hepatitis

authors： Bräu N,Bini EJ,Currie S,Shen H,Schmidt WN,King PD,Ho SB,Cheung RC,Hu KQ,Anand BS,Simon FR,Aytaman A,Johnson DP,Awad JA,Ahmad J,Mendenhall CL,Pedrosa MC,Moseley RH,Hagedorn CH,Waters B,Chang KM,Morgan TR,Rossi

更新日期：2006-04-01 00:00:00

abstract：:Triple therapy using boceprevir or telaprevir remains the reference treatment for genotype 1 chronic hepatitis C in countries where new interferon-free regimens have not yet become available. Antiviral treatment is highly required in cirrhotic patients, but they represent a difficult-to-treat population. We aimed to d...

journal_title：Journal of viral hepatitis

authors： Boursier J,Ducancelle A,Vergniol J,Veillon P,Moal V,Dufour C,Bronowicki JP,Larrey D,Hézode C,Zoulim F,Fontaine H,Canva V,Poynard T,Allam S,De Lédinghen V,ANRS CO20 CUPIC Study Group.

更新日期：2015-12-01 00:00:00

abstract：:Obesity and insulin resistance have been reported as negative predictors for sustained virological response (SVR) in hepatitis C virus (HCV) genotype 1 infected patients treated with pegylated interferon-α plus ribavirin. They are also known to affect serum levels of several cytokines including adipocytokines. But the...

journal_title：Journal of viral hepatitis

authors： Miki D,Ohishi W,Ochi H,Hayes CN,Abe H,Tsuge M,Imamura M,Kamatani N,Nakamura Y,Chayama K

更新日期：2012-02-01 00:00:00

abstract：:The risk of perinatal transmission of hepatitis C virus (HCV) from a cohort of 95 human immunodeficiency virus (HIV)-negative intravenous drug users (IVDU) is described, 89 of whom were positive for antibodies to HCV (anti-HCV). Infection, defined as the presence of HCV RNA in a serum sample collected from an infant a...

journal_title：Journal of viral hepatitis

authors： Spencer JD,Latt N,Beeby PJ,Collins E,Saunders JB,McCaughan GW,Cossart YE

更新日期：1997-01-01 00:00:00

abstract：:Patients with chronic hepatitis B (HBsAg-positive) are at risk of viral reactivation if rituximab is administered without antiviral treatment, a potentially fatal complication of treatment. Patients with so-called 'resolved hepatitis B virus infection' (HBsAg-negative/cAb-positive) may also be at risk. We performed a ...

journal_title：Journal of viral hepatitis

authors： Mozessohn L,Chan KK,Feld JJ,Hicks LK

更新日期：2015-10-01 00:00:00

abstract：:In vitro cell culture experiments and animal models have demonstrated that hepatitis delta virus (HDV) can theoretically propagate being enveloped by human pathogenic viruses other than hepatitis B virus (HBV), namely hepatitis C virus (HCV) and dengue virus. However, the clinical relevance of these findings and wheth...

journal_title：Journal of viral hepatitis

authors： Pflüger LS,Schulze Zur Wiesch J,Polywka S,Lütgehetmann M

更新日期：2021-01-01 00:00:00

abstract：:Long-term safety of treatment with hepatitis B virus (HBV) polymerase inhibitors is a concern. Adefovir dipivoxil (ADV) therapy has previously been associated with impairment of renal function. Limited data are available on the safety of combination therapy with nucleos(t)ide analogues and interferon alfa (IFNα). The ...

journal_title：Journal of viral hepatitis

authors： Mederacke I,Yurdaydin C,Großhennig A,Erhardt A,Cakaloglu Y,Yalcin K,Gurel S,Zeuzem S,Zachou K,Chatzikyrkou C,Bozkaya H,Dalekos GN,Manns MP,Wedemeyer H,Hep-Net\/International Delta Hepatitis Study Group.

更新日期：2012-06-01 00:00:00

abstract：:Hepatitis delta virus (HDV) infection is a usually severe type of viral hepatitis associated with increased mortality and rapid evolution to cirrhosis. Currently, treatment is limited to extended interferon administration and measurement of HDV RNA blood levels is essential to judge the response. The aim of this study...

journal_title：Journal of viral hepatitis

authors： Katsoulidou A,Manesis E,Rokka C,Issaris C,Pagoni A,Sypsa V,Hatzakis A

更新日期：2013-04-01 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMC) from chronic hepatitis C virus-infected persons can harbour viral variants that are not detected in plasma samples. We explored the presence and persistence of HCV genotypes in plasma and PBMC cultures from 25 HCV-monoinfected and 25 HIV/HCV-coinfected patients with haemophili...

journal_title：Journal of viral hepatitis

authors： Parodi C,García G,Monzani MC,Culasso A,Aloisi N,Corti M,Campos R,de E de Bracco MM,Baré P

更新日期：2015-07-01 00:00:00

abstract：:Hepatitis C (HCV) infection can cause cirrhosis, liver cancer and death in the absence of treatment. Many people living in the UK but born overseas are believed to be infected with HCV although many are unlikely to know they are infected. The aim of this study is to assess the potential for a case-finding approach to ...

journal_title：Journal of viral hepatitis

authors： Miners AH,Martin NK,Ghosh A,Hickman M,Vickerman P

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis A incidence has declined in most countries through a combination of prevention measures, augmented through the use of a highly effective vaccine. In Australia, the proportion of the population susceptible to hepatitis A infection has declined over time due to high rates of opportunistic vaccination as well a...

journal_title：Journal of viral hepatitis

authors： Jayasundara D,Hui BB,Regan DG,Heywood AE,MacIntyre CR,Wood JG

更新日期：2019-01-01 00:00:00

abstract：:Advanced age and high hepatitis B virus (HBV) DNA level are risk factors associated with the development of HBV-related hepatocellular carcinoma (HCC). However, little is known about the role of viral load in the carcinogenesis of HCC in young people. A total of 183 HBV-related HCC patients and 202 HBV carriers were t...

journal_title：Journal of viral hepatitis

authors： Tsai FC,Liu CJ,Chen CL,Chen PJ,Lai MY,Kao JH,Chen DS

更新日期：2007-03-01 00:00:00

abstract：:We evaluated the effect of sustained virologic response (SVR) from direct-acting antiviral (DAA)- and interferon-based treatments on hepatocellular carcinoma (HCC) risk in a large population-based cohort in Canada. We used data from the BC Hepatitis Testers Cohort, which includes ~1.3 million individuals tested for HC...

journal_title：Journal of viral hepatitis

authors： Janjua NZ,Wong S,Darvishian M,Butt ZA,Yu A,Binka M,Alvarez M,Woods R,Yoshida EM,Ramji A,Feld J,Krajden M

更新日期：2020-08-01 00:00:00

abstract：:To assess the prevalence of hepatitis delta virus (H delta V) in northern India, 204 adult patients with acute and chronic liver disease who were positive for hepatitis B virus (HBV) markers were screened for anti-H delta V antibody by enzyme-linked immunosorbent assay (ELISA). Anti-H delta V antibodies were positive ...

journal_title：Journal of viral hepatitis

authors： Singh V,Goenka MK,Bhasin DK,Kochhar R,Singh K

更新日期：1995-01-01 00:00:00

abstract：:Children with chronic hepatitis C may be ideal candidates for treatment with interferon alpha (IFNalpha) as they have liver disease at an early stage. However, adverse drug reactions need to be considered. The aim of this study was to conduct a systematic review of literature on interferon therapy of chronic hepatitis...

journal_title：Journal of viral hepatitis

authors： Di Ciommo V,Russo P,Ravà L,Caprino L

更新日期：2003-05-01 00:00:00

abstract：:Haemophilic patients have a high prevalence of hepatitis C virus (HCV) infection because of the use of unsterilized clotting factor concentrates. Six major genotypes of HCV have been distinguished so far, with epidemiological evidence suggesting that genotypes 1-3 are common in the indigenous UK and US populations. Th...

journal_title：Journal of viral hepatitis

authors： Devereux H,Telfer P,Brown D,Morris A,Dusheiko G,Emery V,Lee C

更新日期：1996-01-01 00:00:00

abstract：:For the past decade, a specific hepatitis B virus (HBV) genotype A strain has been prevalent among men having sex with men (MSM) in Amsterdam, the Netherlands. At what point in time this strain was introduced in the MSM population, and why only this specific strain continues to be transmitted, remains unclear. Between...

journal_title：Journal of viral hepatitis

authors： van Houdt R,Bruisten SM,Geskus RB,Bakker M,Wolthers KC,Prins M,Coutinho RA

更新日期：2010-02-01 00:00:00

abstract：:It is unknown whether dynamic changes of liver stiffness measurement (LSM) can predict the reversibility of fibrosis. Therefore, we evaluated the utility of LSM changes in predicting histological changes of fibrosis in patients with chronic hepatitis B (CHB) on antiviral therapy. In a prospective cohort of CHB patient...

journal_title：Journal of viral hepatitis

authors： Kong Y,Sun Y,Zhou J,Wu X,Chen Y,Piao H,Lu L,Ding H,Nan Y,Jiang W,Xu Y,Xie W,Li H,Feng B,Shi G,Chen G,Li H,Zheng H,Cheng J,Wang T,Liu H,Lv F,Shao C,Mao Y,Sun J,Chen T,Han T,Han Y,Wang L,Ou X,Zha

更新日期：2019-05-01 00:00:00

abstract：:Circulating microRNAs (miRNA) have been intensely investigated as biomarkers in disease and therapy. Several studies have identified miR-122 as an important regulator of HCV replication. The effect of new therapies that directly target the HCV replication life cycle on circulating microRNA levels has not been elucidat...

journal_title：Journal of viral hepatitis

authors： Waring JF,Dumas EO,Abel S,Coakley E,Cohen DE,Davis JW,Podsadecki T,Dutta S

更新日期：2016-02-01 00:00:00

abstract：:A randomized trial was conducted to assess the efficacy of interferon-alpha (IFN) daily in combination with ribavirin in 301 naïve patients with chronic hepatitis C (CHC). Patients were randomized to receive ribavirin 1.2 g daily (QD) for 48 weeks with either IFN 5 MU (thrice weekly) TIW for 8 weeks followed by IFN 3 ...

journal_title：Journal of viral hepatitis

authors： Tassopoulos NC,Ketikoglou I,Tsantoulas D,Raptopoulou M,Hatzis G,Vafiadis I,Sidiropoulos L,Kanatakis S,Anagnostopoulos G,Sypsa V,Hatzakis A,Hellenic Viral Hepatitis Research Network.

更新日期：2003-09-01 00:00:00

abstract：:We assessed the efficacy of prolonged interferon-alpha (IFN) therapy in children with chronic hepatitis caused by hepatitis delta virus (HDV) by treating 26 paediatric cases with IFN-alpha 2b (5 MU m-2, then 3 MU m-2 three times weekly for 12 (medium-term group MTG) or 24 months (long-term group, LTG). Compliance and ...

journal_title：Journal of viral hepatitis

authors： Di Marco V,Giacchino R,Timitilli A,Bortolotti F,Crivellaro C,Calzia R,Iannuzzi C,Prestileo T,Vajro P,Nebbia G,Stringhi C,Rosina F,Biassoni D,Callea F,Rizzetto M,Craxi A

更新日期：1996-05-01 00:00:00

abstract：:Anaemia during peginterferon (PEG-IFN) and ribavirin (RBV) therapy is common in human immunodeficiency virus/hepatitis C virus (HIV/HCV)-coinfected patients despite the use of lower doses of RBV than are recommended for HIV-seronegative persons. In addition, concurrent zidovudine (ZDV) may exacerbate the anaemia cause...

journal_title：Journal of viral hepatitis

authors： Alvarez D,Dieterich DT,Brau N,Moorehead L,Ball L,Sulkowski MS

更新日期：2006-10-01 00:00:00

abstract：:The World Health Organization has set the goal of reducing the hepatitis-related mortality rate by 65% between 2015 and 2030. Diagnosis and awareness of infection is the first essential step towards achieving this goal. Our study examined the current awareness rate of chronic viral hepatitis in the United States and t...

journal_title：Journal of viral hepatitis

authors： Kim HS,Yang JD,El-Serag HB,Kanwal F

更新日期：2019-05-01 00:00:00

abstract：:The effect of direct-acting antiviral (DAA) therapy on extracellular matrix (ECM) turnover, a prominent feature of chronic hepatitis C (CHC), is unknown. ECM protein degradation and formation generate fragments reflecting the tissue turnover balance when quantified in the blood. PRO-C3 and PRO-C4 reflect type III and ...

journal_title：Journal of viral hepatitis

authors： Laursen TL,Villesen IF,Leeming DJ,Karsdal MA,Sølund C,Tarp B,Kristensen LH,Holmboe CH,Leutscher P,Laursen AL,Gudmann NS,Grønbaek H

更新日期：2021-02-01 00:00:00

abstract：SUMMARY:Hepatitis C virus (HCV) genotypes 1 and 4 respond less well to pegylated interferon (pegIFN) plus ribavirin (RBV) therapy. For this reason most studies merge these two genotypes when assessing virological response. However, in most trials the HCV genotype 4 population is rather small, and conclusions are mainly...

journal_title：Journal of viral hepatitis

authors： Martín-Carbonero L,Puoti M,García-Samaniego J,De Luca A,Losada E,Quinzan G,Bruno R,Mariño A,González M,Núñez M,Soriano V

更新日期：2008-10-01 00:00:00

abstract：:Limited data are available on direct-acting antivirals for treating hepatitis C virus (HCV) infection in patients with severe renal impairment. The aim of this study was to evaluate the effectiveness and safety of ombitasvir/paritaprevir/ritonavir (OBV/PTV/r) ± dasabuvir (DSV) ± ribavirin (RBV) in patients with stage ...

journal_title：Journal of viral hepatitis

authors： Muñoz-Gómez R,Rincón D,Ahumada A,Hernández E,Devesa MJ,Izquierdo S,Ortiz M,Hernández-Albujar A,Fernández-Rodríguez C,Calvo M,González R,Lozano M,Castellano G,Fernández-Vázquez I

更新日期：2017-06-01 00:00:00

abstract：:To achieve WHO hepatitis C virus (HCV) elimination targets by 2030, mathematical models suggest there needs to be significant scale-up of treatment among people who inject drugs (PWID). We tested whether people who actively inject drugs can be recruited and treated successfully through a community needle and syringe p...

journal_title：Journal of viral hepatitis

authors： Schulkind J,Stephens B,Ahmad F,Johnston L,Hutchinson S,Thain D,Ward Z,Vickerman P,Hickman M,Dillon JF

更新日期：2019-05-01 00:00:00

abstract：:Understanding local viral hepatitis and HIV epidemiology is essential if WHO elimination targets are to be achieved. We demonstrate a consistently high prevalence of undiagnosed active infection in urban emergency department attendees in England, with variations in local risk groups crucial to informing targeted testi...

journal_title：Journal of viral hepatitis

authors： Hopkins MJ,Todd S,Beadsworth M,Anderson C,Mohamed Z,Muir D,Vivancos R,Brown AS,Ruf M,Chawla A

更新日期：2020-01-01 00:00:00