Murine trophoblast cells are not killed by tumor necrosis factor-alpha.

abstract：:Pre-eclampsia (PE) remains the leading cause of pregnancy-associated mortality and morbidity, urging the need for a better understanding of its aetiology and pathophysiological progression. A key characteristic of PE is a systemic, exaggerated, inflammatory condition involving abnormal cytokine levels in serum, altere...

journal_title：Journal of reproductive immunology

authors： Al-ofi E,Coffelt SB,Anumba DO

更新日期：2014-06-01 00:00:00

abstract：:This review will highlight recent advances in the study of the immuno-endocrinology of the testis, in particular how macrophage-derived inflammatory mediators affect Leydig cell functions. Both the beneficial and deleterious outcomes resulting from macrophage-Leydig cell interactions are discussed. A brief overview of...

journal_title：Journal of reproductive immunology

authors： Hales DB

更新日期：2002-10-01 00:00:00

abstract：:Substrains of BALB/c mice differ in their susceptibility to experimental autoimmune orchitis (EAO), with BALB/cJ representative of the non-responders and BALB/cBy representative of the responders. We examined whether the susceptibility of these two substrains could be altered by reciprocal adoptive transfer of lymphoi...

journal_title：Journal of reproductive immunology

authors： Mahi-Brown CA,Tung KS

更新日期：1990-10-01 00:00:00

abstract：:Viviparity has many evolutionary advantages but brings with it the problem of the semi-allogeneic foetus having to coexist with the mother for the duration of pregnancy. In species with haemochorial placentation this problem is particularly evident as foetal trophoblast cells are extensively intermingled with maternal...

journal_title：Journal of reproductive immunology

authors： Hemberger M

更新日期：2013-03-01 00:00:00

abstract：:In this review, we summarize the results of a number of our recent in vitro and in vivo experiments demonstrating that, in addition to the immunoregulatory functions, soluble HLA-G molecules also affect endothelial cell activity. We have found that soluble HLA-G1 (also designated HLA-G5) inhibits endothelial cell prol...

journal_title：Journal of reproductive immunology

authors： Le Bouteiller P,Fons P,Herault JP,Bono F,Chabot S,Cartwright JE,Bensussan A

更新日期：2007-12-01 00:00:00

abstract：:Sperm antigens are being sought for the development of prototype contraceptive vaccines. For vaccine-induced antisperm antibodies to inhibit the function of viable sperm, target antigens must be expressed on the sperm surface before, during or after the acrosome reaction. The purpose of this study was to develop an ap...

journal_title：Journal of reproductive immunology

authors： Fichorova R,Anderson DJ

更新日期：1991-05-01 00:00:00

abstract：:The objective of these experiments was to determine the effects of neonatal thymectomy on the induction of experimental autoimmune orchitis in inbred rats of the Fischer 344 and Lewis strains. It was found that thymectomy alone in Lewis rats, and thymectomy followed by immunization with testicular extract in both Lewi...

journal_title：Journal of reproductive immunology

authors： Lipscomb HL,Gardner PJ,Sharp JG

更新日期：1979-12-01 00:00:00

abstract：:The debate about the presence of HIV-1 particles in human gametes and recent experimental results are reported in detail. Using immunocytochemistry, in situ hybridization at electron microscopy level, polymerase chain reaction and in vitro fertilization, it has been demonstrated that human spermatozoa can incorporate ...

journal_title：Journal of reproductive immunology

authors： Baccetti B,Benedetto A,Collodel G,di Caro A,Garbuglia AR,Piomboni P

更新日期：1998-12-01 00:00:00

abstract：:A rat monoclonal antibody (5D4) apparently specific for murine embryonal carcinoma cells and cells of the pre-implantation embryo is described. It does not react with differentiated cells from a variety of different tumours and tissues of the mouse. Biochemical studies show that the molecules that carry 5D4 antigen ar...

journal_title：Journal of reproductive immunology

authors： Stern PL,Gilbert P,Heath JK,Furth M

更新日期：1983-05-01 00:00:00

abstract：:Human trophoblast membrane antigens recognised by monoclonal antibodies (H310, H315, H316 and H317) have been identified using combinations of radioimmunoprecipitation, SDS-PAGE, electroblotting, chromatographic and ELISA-type techniques. H317 is known to identify heat-stable placental-type alkaline phosphatase and ac...

journal_title：Journal of reproductive immunology

authors： Brown PJ,Molloy CM,Johnson PM

更新日期：1983-11-01 00:00:00

abstract：:Antisperm autoantibodies were studied in Fischer and Lewis strains of rats after either vasectomy, vasectomy followed one month later by vasovasostomy, or sham operations. The time course of antibody response to sperm protein autoantigens was assayed by Western blot analysis of sera obtained at intervals up to 3 month...

journal_title：Journal of reproductive immunology

authors： Flickinger CJ,Howards SS,Bush LA,Baker LA,Herr JC

更新日期：1995-02-01 00:00:00

abstract：:Interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) were identified in samples of first trimester and term placentas by immunocytochemistry using two sets of polyclonal antibodies to recombinant IL-1. All samples contained the two species of IL-1, which predominated in different types of cells: IL-1 al...

journal_title：Journal of reproductive immunology

authors： Hu XL,Yang Y,Hunt JS

更新日期：1992-10-01 00:00:00

abstract：:We have previously shown that DBA/1 mice immunized with heterologous type II collagen showed remission of the subsequent collagen-induced arthritis (CIA) when pregnant, but experienced exacerbation postpartum. Measurement of anticollagen antibody (aCa) responses by ELISA in primiparous mice immunized at day 1 of pregn...

journal_title：Journal of reproductive immunology

authors： Whyte A,Hasan Z,Rutter F

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the sex specific expression of histone protein modifications responsible for rapid gene expression in IUGR placentas. PATIENTS AND METHODS:We screened for fetal sex-specific expression of the histone proteins H3K4me3 and H3K9ac in 23 IUGR and 40 control placentas...

journal_title：Journal of reproductive immunology

authors： Meister S,Kolben T,Beyer S,Hutter S,Hofmann S,Kuhn C,Messner J,Mayr D,Solano ME,Jegen M,Obermeier V,Mahner S,Arck P,Jeschke U

更新日期：2020-06-01 00:00:00

abstract：:There is now evidence that the classical HLA class I molecule HLA-C is expressed on extravillous trophoblasts together with non-classical HLA-G molecules. Since clones of NK-cells are inhibited differently by supertypic epitopes associated with HLA-C and -B alleles we found it of interest to study HLA-C and -Bw polymo...

journal_title：Journal of reproductive immunology

authors： Christiansen OB,Mohapeloa HP,Steffensen R,Jersild C

更新日期：1997-12-15 00:00:00

abstract：:Reproductive immunology applies general immunology principles to specialised targets, reproduction and development. The involvement of colony-stimulating factors (CSFs) in reproduction illustrates this. The CSF family includes CSF-1 or macrophage CSF (M-CSF), CSF-2 or granulocyte macrophage CSF (GM-CSF), and CSF-3 or ...

journal_title：Journal of reproductive immunology

authors： Rahmati M,Petitbarat M,Dubanchet S,Bensussan A,Chaouat G,Ledee N

更新日期：2015-06-01 00:00:00

abstract：:Macrophages are a prominent resident cell type in the interstitial tissue of the testis in several mammalian species. This presence in an immunologically-privileged site prompted an investigation of their ability to initiate and regulate lymphocyte proliferation in vitro. Isolated rat peripheral blood lymphocytes (PBL...

journal_title：Journal of reproductive immunology

authors： Kern S,Maddocks S

更新日期：1995-03-01 00:00:00

abstract：:The regulation of uterine and circulating peripheral blood natural killer (NK) cells has been associated with reproductive conditions including recurrent pregnancy loss (RPL), implantation failure and preeclampsia. Natural cytotoxicity receptors (NCRs) are unique markers that regulate NK cell cytotoxicity and cytokine...

journal_title：Journal of reproductive immunology

authors： Fukui A,Funamizu A,Yokota M,Yamada K,Nakamua R,Fukuhara R,Kimura H,Mizunuma H

更新日期：2011-06-01 00:00:00

abstract：:Syncytiotrophoblast microvillous plasma membrane (StMPM) preparations were obtained from human full-term placentae by previously published methods of cold saline extraction and phase centrifugation. Purity of these preparations was assessed by electron microscopy, enzyme analysis and hydroxyproline content. IgG, album...

journal_title：Journal of reproductive immunology

authors： Ogbimi AO,Johnson PM,Brown PJ,Fox H

更新日期：1979-07-01 00:00:00

abstract：:Thyroid autoimmunity (TAI) appears to play a crucial role in female infertility, recurrent pregnancy loss and IVF failure. Thyroid autoantibodies against thyroid peroxidase and thyroglobulin have been shown to represent an independent risk factor for infertility and miscarriage. Moreover, thyroxin hormone administrati...

journal_title：Journal of reproductive immunology

authors： Miko E,Meggyes M,Doba K,Farkas N,Bogar B,Barakonyi A,Szereday L,Szekeres-Bartho J,Mezosi E

更新日期：2017-11-01 00:00:00

abstract：:Pregnancy-induced hypertension (PIH) can be complicated by maternal or fetal thrombocytopenia, or both. In order to investigate possible immunologic causes of these thrombocytopenias, platelet-associated IgG (PAIgG) and IgM (PAIgM) were measured in mothers with PIH and in their infants and compared with those from pat...

journal_title：Journal of reproductive immunology

authors： Rote NS,Lau RJ,Harrison MR,Branch DW,Scott JR

更新日期：1987-04-01 00:00:00

abstract：:We previously reported that decidual stromal cells (DSC) from early human decidua express antigens associated with hematopoietic cells and develop different immune functions. Here we study the antigenic phenotype of DSC from term decidua and compare it with the phenotype reported for DSC from early decidua. Decidual s...

journal_title：Journal of reproductive immunology

authors： Oliver C,Cowdrey N,Abadía-Molina AC,Olivares EG

更新日期：1999-11-01 00:00:00

abstract：:Controversy exists as to whether active immunotherapy with allogeneic lymphocyte transfusions (ALT) or passive immunotherapy with intravenous immunoglobulin (IvIg) improve the chance of live birth in women with unexplained recurrent miscarriages (RM). Meta-analyses of the placebo-controlled trials carried out as Cochr...

journal_title：Journal of reproductive immunology

authors： Christiansen OB,Nielsen HS,Pedersen B

更新日期：2004-06-01 00:00:00

abstract：:The structure of a high-molecular-weight form of Pregnancy-Specific beta 1-Glycoprotein designated PSB1G-I that had been previously isolated from maternal serum was studied by gel chromatography in guanidine hydrochloride dissociating solvent. Evidence was obtained that subunits of identical size (bonded together non-...

journal_title：Journal of reproductive immunology

authors： Griffiths BW,Godard A

更新日期：1981-06-01 00:00:00

abstract：:During the past 40 years, polybrominated diphenyl ethers (PBDEs) have been widely used as flame retardants and nearly all women have some level of exposure. PBDEs have been isolated from amniotic fluid and cord plasma indicating vertical transmission; however, their effects on pregnancy outcome are largely unknown. Th...

journal_title：Journal of reproductive immunology

authors： Peltier MR,Koo HC,Getahun D,Menon R

更新日期：2015-02-01 00:00:00

abstract：:Lipopolysaccharide (LPS, endotoxin) is a component of the cell wall of gram-negative bacteria and a potent inducer of severe inflammatory reactions. In mice, systemically administered LPS induces fetal resorption and increases fetal mortality. However, effects of intrauterine LPS on fertility, fetal survival and devel...

journal_title：Journal of reproductive immunology

authors： Tuo W,Ott TL,Liu S,Bazer FW

更新日期：1999-01-01 00:00:00

abstract：:Herpes simplex virus type 2 (HSV-2) is becoming increasingly prevalent worldwide, despite the widespread use of antiviral drugs. Its ability to evade the immune system and establish a latent infection has made it difficult to develop an effective vaccine. Our understanding of the immune response against HSV-2 remains ...

journal_title：Journal of reproductive immunology

authors： Chan T,Barra NG,Lee AJ,Ashkar AA

更新日期：2011-03-01 00:00:00

abstract：:Recurrent implantation failure (RIF) refers to cases in which women have had the failure of the embryo implantation after several in vitro fertilization (IVF). The success rate for IVF depends on many different factors. Implantation is a complex step in a successful pregnancy. Antiphospholipid antibodies (aPLs) and pl...

journal_title：Journal of reproductive immunology

authors： Mahdian S,Pirjani R,Favaedi R,Movahedi M,Moini A,Shahhoseini M

更新日期：2021-02-01 00:00:00

abstract：:Pregnancy success is attributed to the joint action of several factors such as regulatory placental molecules and components of the mother's immune system, among others. Asymmetrical glycosilated and functionally univalent IgG antibodies are suggested to influence the immune balance between the mother and foetus, play...

journal_title：Journal of reproductive immunology

authors： Gutiérrez G,Malan Borel I,Margni RA

更新日期：2001-01-01 00:00:00

abstract：:Lipopolysaccharide-binding protein (LBP) is an acute phase protein known to play a central role in the defense against Gram-negative bacteria. It binds lipopolysaccharides of Gram-negative bacteria and, after binding to CD14, the complex signals through Toll-like receptor (TLR)-4, eliciting host-defense responses, suc...

journal_title：Journal of reproductive immunology

authors： Malm J,Nordahl EA,Bjartell A,Sørensen OE,Frohm B,Dentener MA,Egesten A

更新日期：2005-06-01 00:00:00