Abstract：
:Protein-polymer conjugates are of interest to researchers in diverse fields. Attachment of polymers to proteins results in improved pharmacokinetics, which is important in medicine. From an engineering standpoint, conjugates are exciting because they exhibit properties of both the biomolecules and synthetic polymers. This allows the activity of the protein to be altered or tuned, anchoring to surfaces, and supramolecular self-assembly. Thus, there is broad interest in straightforward synthetic methods to prepare protein-polymer conjugates. Controlled radical polymerization (CRP) techniques have emerged as excellent strategies to make conjugates because the resulting polymers have narrow molecular weight distributions, targeted molecular weights, and attach to specific sites on proteins. Herein, recent advances in the synthesis and application of protein-polymer conjugates by CRP are highlighted.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Grover GN,Maynard HDdoi
10.1016/j.cbpa.2010.10.008subject
Has Abstractpub_date
2010-12-01 00:00:00pages
818-27issue
6eissn
1367-5931issn
1879-0402pii
S1367-5931(10)00149-3journal_volume
14pub_type
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journal_title：Current opinion in chemical biology
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