Comparison of methods to detect HIV dual infection.

abstract：:Mucosal candidiasis is a common complication of HIV infection and HIV-positive women may develop both oropharyngeal and vaginal disease. Colonization with Candida albicans and related species at either site is a common preceding event in asymptomatic women. To examine the molecular epidemiology of colonizing yeast str...

journal_title：AIDS research and human retroviruses

authors： Dahl KM,Keath EJ,Fraser VJ,Powderly WG

更新日期：1997-04-10 00:00:00

abstract：:In order to obtain more information about the presence of HIV-1 in mononuclear cells of colostrum, research was carried out on both the HIV-1 genome in the cellular fraction of colostrum and the viral antibody in cell-free colostrum of eight anti-HIV-1 seropositive asymptomatic mothers. In five cases cell fractions of...

journal_title：AIDS research and human retroviruses

authors： Vonesch N,Sturchio E,Humani AC,Cordiali Fei P,Cosenza D,Caprilli F,Pezzella M

更新日期：1992-07-01 00:00:00

abstract：:Cyanovirin-N (CV-N), an 11-kDa cyanobacterial protein, potently inactivates diverse strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) and also prevents virus-to-cell fusion, virus entry, and infection of cells in vitro. These properties make CV-N an attractive candidate for use as a topical microbicide ...

journal_title：AIDS research and human retroviruses

authors： Tsai CC,Emau P,Jiang Y,Tian B,Morton WR,Gustafson KR,Boyd MR

更新日期：2003-07-01 00:00:00

abstract：:Epidemiological and experimental data suggest that both robust neutralizing antibodies and potent cellular responses play important roles in controlling primary HIV-1 infection. In this study we have investigated the induction of systemic and mucosal immune responses to HIV gp120 monomer immunogen administered intrana...

journal_title：AIDS research and human retroviruses

authors： Bielinska AU,Janczak KW,Landers JJ,Markovitz DM,Montefiori DC,Baker JR Jr

更新日期：2008-02-01 00:00:00

abstract：:The clinical significance of the reduced in vitro susceptibility of HIV to antiretroviral agents has been difficult to elucidate for nucleoside analogs such as zidovudine. However, the virological significance of resistance to nevirapine and other HIV-1-specific reverse transcriptase inhibitors has been established. W...

journal_title：AIDS research and human retroviruses

authors： Richman DD

更新日期：1994-08-01 00:00:00

abstract：:India has experienced multiple introductions of diverse HIV-1 subtypes A, B, C, and E, along with subtype B of HIV-2 between the 1980s and early 1990s. In this study, we have carried out a molecular investigation of 21 heterosexually and vertically acquired HIV-infected individuals from the New Bombay area, who tested...

journal_title：AIDS research and human retroviruses

authors： Halani N,Wang B,Ge YC,Gharpure H,Hira S,Saksena NK

更新日期：2001-05-01 00:00:00

abstract：:Subunit vaccines based on recombinant proteins have proved useful for inducing antibody responses and they are safe for widespread use because they do not contain any live components. Unfortunately, they do not typically induce the types of cell-mediated immune responses required to control viral pathogens; specifical...

journal_title：AIDS research and human retroviruses

authors： Newman MJ,Munroe KJ,Anderson CA,Murphy CI,Panicali DL,Seals JR,Wu JY,Wyand MS,Kensil CR

更新日期：1994-07-01 00:00:00

abstract：:Most viral vaccines currently in use in humans are live attenuated strains of virus that lack pathogenic potential. In general, such live attenuated vaccines induce the strongest longest-lasting immunity. Live attenuated strains of human immunodeficiency virus type 1 (HIV-1) have not been previously considered as vacc...

journal_title：AIDS research and human retroviruses

authors： Desrosiers RC

更新日期：1992-03-01 00:00:00

abstract：:In recent years, increasing numbers of patients infected with HIV-1 non-B subtypes have been treated with modern antiretroviral regimens. Therefore, a better knowledge of HIV drug resistance in non-B strains is crucial. Thus, we compared the mutational pathways involved in drug resistance among the most common non-B s...

journal_title：AIDS research and human retroviruses

authors： Santoro MM,Alteri C,Ronga L,Flandre P,Fabeni L,Mercurio F,D'Arrigo R,Gori C,Palamara G,Bertoli A,Forbici F,Salpini R,Boumis E,Tozzi V,Visco-Comandini U,Zaccarelli M,Van Houtte M,Pattery T,Narciso P,Antinori A,Cecc

更新日期：2012-10-01 00:00:00

abstract：:We studied 123 samples from adult chronic HIV patients initiating HAART from various centers around a newly established clinical trial site in Pretoria. Each sample was sequenced in at least one structural gene (pol, gag, and env) or functional gene (vif, vpr, and vpu). A subset of 25 samples was subjected to near ful...

journal_title：AIDS research and human retroviruses

authors： Musyoki A,Mothapo K,Rakgole J,Lukhwareni A,Bessong P,Selabe G,Bredell H,Williamson C,Mphahlele MJ

更新日期：2012-09-01 00:00:00

abstract：:Previous studies have shown that coinfection of the human T lymphotrophic virus type I (HTLV-I) chronically infected cell line MT4 with human immunodeficiency virus type 1 (HIV-1) results in cells which spontaneously activate complement via the classical pathway. This complement activation was antibody independent, ye...

journal_title：AIDS research and human retroviruses

authors： Spear GT,Jiang HX,Sullivan BL,Gewurz H,Landay AL,Lint TF

更新日期：1991-07-01 00:00:00

abstract：:Vaginal anti-HIV antibody responses may be beneficial, and possibly required, for vaccine-induced protection against HIV infection acquired through receptive vaginal intercourse. We have previously determined that intranasal immunization with a hybrid HIV peptide and cholera toxin induced vaginal anti-HIV IgA response...

journal_title：AIDS research and human retroviruses

authors： Staats HF,Montgomery SP,Palker TJ

更新日期：1997-07-20 00:00:00

abstract：:We report the results of an external quality control program, including 17 Italian centers involved in the care of patients infected by HIV, to evaluate CD4 T cell count proficiency and reproducibility. The centers received two commercial stabilized blood preparations, one with "normal" and one with "low" CD4 T cell c...

journal_title：AIDS research and human retroviruses

authors： Martini F,D'Offizi G,Girardi E,Vitale A,Cimini E,Mollicone B,Vlassi C,Aiuti F,Other Members of 2005 Italian CD4 Quality Control Network.

更新日期：2007-06-01 00:00:00

abstract：:We identified an HIV-1 variant that belongs to the M group, with limited similarity of short genetic regions (100-200 nt) to subtype K, but the remainder of the genome is unrelated to any established HIV-1 subtype. The isolate was obtained from an HIV-1-positive male, living in the Netherlands, who encountered the vir...

journal_title：AIDS research and human retroviruses

authors： van der Hoek L,Pollakis G,Lukashov VV,Jebbink MF,Jeeninga RE,Bakker M,Dukers N,Jurriaans S,Paxton WA,Back NK,Berkhout B

更新日期：2007-03-01 00:00:00

abstract：:This study examines the association between presence of drug resistance mutations and phenotypic resistance at baseline to virologic response to salvage therapy in a community setting. The study population consisted of 58 antiretroviral drug-experienced patients with HIV-1 infection who had recently switched therapy b...

journal_title：AIDS research and human retroviruses

authors： Ross L,Liao Q,Gao H,Pham S,Tolson J,Hertogs K,Larder B,Saag MS

更新日期：2001-10-10 00:00:00

abstract：:Glutamine is a conditionally essential amino acid that is an important metabolic resource for proliferating tissues by acting as a proteinogenic amino acid, a nitrogen donor for biosynthetic reactions and as a substrate for the citric acid or tricarboxylic acid cycle. The human immunodeficiency virus type 1 (HIV-1) pr...

journal_title：AIDS research and human retroviruses

authors： Hegedus A,Kavanagh Williamson M,Khan MB,Dias Zeidler J,Da Poian AT,El-Bacha T,Struys EA,Huthoff H

更新日期：2017-12-01 00:00:00

abstract：:The membrane glycolipids galactosylceramide (GalCer) and sulfatide (SGalCer) have been reported to act as receptors of human immunodeficiency virus (HIV) on CD4- cell lines. We show here that these glycolipids are present on CD4+ cells purified from human blood and on in vitro-differentiated monocyte-derived macrophag...

journal_title：AIDS research and human retroviruses

authors： Seddiki N,Ben Younes-Chennoufi A,Benjouad A,Saffar L,Baumann N,Gluckman JC,Gattegno L

更新日期：1996-05-20 00:00:00

abstract：:Lymphoid tissues are the focus of critical events in HIV pathogenesis. Persistent and high levels of virus production, extensive trapping of virus particles in germinal centers, and progressive degenerative changes in lymph node architecture are characteristics of progressive HIV-1 infection. Infiltrates of granzyme B...

journal_title：AIDS research and human retroviruses

authors： Koopman G,Haaksma AG,ten Velden J,Hack CE,Heeney JL

更新日期：1999-03-01 00:00:00

abstract：:Up to now, all known env subtype E viruses (CRF01-AE) have had the same mosaic structure with subtype A, and no other env subtype E HIV-1 viruses with non-A subtypes in their genomes have been described. In this report we describe the full-length genome sequence of an env subtype E isolate with a recombinant genome di...

journal_title：AIDS research and human retroviruses

authors： Vidal N,Mulanga-Kabeya C,Nzilambi N,Delaporte E,Peeters M

更新日期：2000-12-10 00:00:00

abstract：:We have previously used immunotoxins to select for HIV-1 variant cells that transcribe HIV at extremely low levels and fail to produce HIV proteins. Further observation of one of these variants (E9) demonstrated spontaneous in vitro activation of HIV production. The mechanism of activation is different from that of U1...

journal_title：AIDS research and human retroviruses

authors： Fang H,Pincus S

更新日期：1999-10-10 00:00:00

abstract：:Cross-sectional laboratory data were used to model the patterns of total lymphocyte count and lymphocyte subpopulation counts among persons with chronic HIV-1 subtype E (CRF01_AE) infection during the 6.5 years preceding death. The data cover 331 HIV-infected decedents from a heterosexual HIV transmission study of 590...

journal_title：AIDS research and human retroviruses

authors： Kingkeow D,Heilig CM,Costello C,Sennun S,Suriyanon V,Rungruengthanakit K,Taejaroenkul S,Nelson KE,Duerr A

更新日期：2004-06-01 00:00:00

abstract：:HIV-1 disease is associated with many infectious and neoplastic complications. This is particularly true of the genitourinary tract, where high rates of renal disease, neoplasms, voiding and erectile dysfunction, hematuria, opportunistic genitourinary infections, and epididymo-orchitis are found in HIV-1-infected indi...

journal_title：AIDS research and human retroviruses

authors： Coburn M

更新日期：1998-04-01 00:00:00

abstract：:We have studied a woman with transfusion-acquired HIV who appears to have contained infectious virus to consistently undetectable levels over a 13-year period without antiviral treatment. She received the infected transfusion for intra- and postpartum blood loss immediately after delivery of her second child in 1981. ...

journal_title：AIDS research and human retroviruses

authors： Schwartz D,Sharma U,Busch M,Weinhold K,Matthews T,Lieberman J,Birx D,Farzedagen H,Margolick J,Quinn T

更新日期：1994-12-01 00:00:00

abstract：:The antiretroviral (ARV) service at Edendale Hospital in Pietermaritzburg, KwaZulu-Natal, South Africa has initiated more than 9,000 adults on therapy since 2004; however, virological outcomes among this patient cohort have not been systematically assessed. We conducted a retrospective chart review of patients initiat...

journal_title：AIDS research and human retroviruses

authors： Costiniuk CT,Sigal A,Jenabian MA,Nijs P,Wilson D

更新日期：2014-06-01 00:00:00

abstract：:We used enzyme-linked immunosorbant assay (ELISA) and Western blotting, with "purified" human T-cell leukemia virus I (HTLV-I), to test for HTLV-I antibodies in 2583 plasma samples from 1053 leukemia/lymphoma patients treated at Roswell Park Memorial Institute, mostly between 1972 and 1984, and in 110 sera samples fro...

journal_title：AIDS research and human retroviruses

authors： Srivastava BI,Gonzales C,Loftus R,Fitzpatrick JE,Saxinger CW

更新日期：1990-05-01 00:00:00

abstract：:Transition from latency to active replication is a crucial stage for the process of human immunodeficiency virus type 1 (HIV-1) infection and life cycle. HIV-1 replication in latently infected cells can be strongly induced by the cytokine tumor necrosis factor alpha (TNF-alpha) and the proliferation-arresting chemical...

journal_title：AIDS research and human retroviruses

authors： Moulton S,Pantazis P,Epstein JS,Sadaie MR

更新日期：1998-01-01 00:00:00

abstract：:Replacing the Pseudomonas exotoxin A (PE) cell binding domain with the human immunodeficiency virus (HIV) gp120 binding domain from CD4 yields a hybrid toxin (CD4-PE) with potential therapeutic use in treating acquired immunodeficiency syndrome (AIDS). To find the most therapeutically potent combination of CD4 and PE ...

journal_title：AIDS research and human retroviruses

authors： Winkler G,Jakubowski A,Turner S,Liu T,Burrus B,McGray P,Heanue T,Rosa M,Griffiths BA,Wali A

更新日期：1991-04-01 00:00:00

abstract：:HGP-30-KLH vaccine in alum at doses of 10, 25, 50, and 100 micrograms/kg administered intramuscularly at weeks 0, 4, and 10 appear well-tolerated clinically. Local pain at the injection site, appears to be the main clinical toxicity. Laboratory parameters are not affected by administration of the vaccine candidate exc...

journal_title：AIDS research and human retroviruses

authors： Kahn JO,Stites DP,Scillian J,Murcar N,Stryker R,Volberding PA,Naylor PH,Goldstein AL,Sarin PS,Simmon VF

更新日期：1992-08-01 00:00:00

abstract：:Previous studies have suggested that the abilities of human immunodeficiency virus type 1 (HIV-1) to infect primary macrophages and transformed T cell lines are mutually exclusive and define an important biological distinction among HIV-1 strains. In a survey of eight macrophage-tropic HIV-1 strains and nine T cell li...

journal_title：AIDS research and human retroviruses

authors： Chowdhury IH,Potash MJ,Volsky DJ

更新日期：1995-12-01 00:00:00

abstract：:Most HIV-1 transmissions occur at mucosae and involve exposure to semen. Semen contains immunomodulatory factors, which inhibit anti-HIV-1 natural killer cell and T cell responses. We demonstrate high concentrations (1:2 dilution) of seminal plasma (SP) inhibit monocyte phagocytosis and anti-HIV-1 Fc-dependent functio...

journal_title：AIDS research and human retroviruses

authors： Selva KJ,Juno JA,Worley MJ,Chung AW,Tachedjian G,Kent SJ,Parsons MS

更新日期：2019-06-01 00:00:00