The 2005 Italian Quality Control Study for the evaluation of CD4 cells in centers involved in the treatment of HIV type 1 patients.

Abstract:

:We report the results of an external quality control program, including 17 Italian centers involved in the care of patients infected by HIV, to evaluate CD4 T cell count proficiency and reproducibility. The centers received two commercial stabilized blood preparations, one with "normal" and one with "low" CD4 T cell content. The centers were asked to process the samples two times, 1 week apart, with the same procedure used for samples from HIV patients. Most centers showed a good performance of CD4 frequency and absolute count determinations. In particular, the "low" sample was correctly analyzed by all centers; only two underestimated the "normal" sample CD4 frequency, and only one underestimated the CD4 absolute count by >100 CD4 cells/microl. Overall, our data suggest that most Italian laboratories provide reliable and reproducible results in evaluating CD4 T cells in HIV(+) samples.

authors

Martini F,D'Offizi G,Girardi E,Vitale A,Cimini E,Mollicone B,Vlassi C,Aiuti F,Other Members of 2005 Italian CD4 Quality Control Network.

doi

10.1089/aid.2006.0295

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

777-81

issue

6

eissn

0889-2229

issn

1931-8405

journal_volume

23

pub_type

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