The role of comorbid disruptive behavior in the clinical expression of pediatric obsessive-compulsive disorder.

Abstract:

:This study explored the impact of disruptive behavior disorder (DBD) comorbidity on a number of theoretically relevant outcomes among 192 children and adolescents with obsessive-compulsive disorder (OCD). Youth were divided into three groups: OCD Only, OCD+DBD comorbidity and OCD+Other comorbidity. Relative to those without a comorbid condition and those with any non-DBD comorbidity, comorbid DBD was associated with greater family accommodation and less symptom resistance. Youth with comorbid DBD exhibited greater OCD symptom severity, OCD-related impairment, anxiety, and internalizing problems than those with no comorbidity. Those with comorbid DBD were over 3.6 times as likely to be taking an atypical antipsychotic medication relative to children without comorbidity. The present results suggest that comorbid DBD contributes to more severe illness presentation above and beyond an OCD diagnosis alone, and may be associated with differing pharmacotherapy prescribing practices.

journal_name

Behav Res Ther

authors

Storch EA,Lewin AB,Geffken GR,Morgan JR,Murphy TK

doi

10.1016/j.brat.2010.09.004

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1204-10

issue

12

eissn

0005-7967

issn

1873-622X

pii

S0005-7967(10)00187-7

journal_volume

48

pub_type

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