Effective bronchodilator treatment by a simple spacer device for wheezy premature infants.

Abstract:

:Ten preterm infants with recurrent respiratory symptoms (median gestational age 30 weeks) were entered into a non-randomised placebo controlled trial of bronchodilator treatment at 12.5 months of age. The infants had coughed or wheezed, or both, on at least four days a week for the past month. The infants received either placebo or 500 micrograms terbutaline from an inhaler using a coffee cup as a spacer device. Each treatment was maintained for two weeks, first placebo then active drug. The symptom score was reduced by 65% during the active treatment period compared with the placebo period and this was associated with a 32% improvement in lung function, reflected in an increase in functional residual capacity. We conclude that inhaled bronchodilator treatment given with a simple spacer device is useful for preterm infants with recurrent respiratory symptoms in the first two years of life.

journal_name

Arch Dis Child

authors

Yuksel B,Greenough A,Maconochie I

doi

10.1136/adc.65.7.782

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

782-5

issue

7

eissn

0003-9888

issn

1468-2044

journal_volume

65

pub_type

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