Abstract:
RATIONALE:Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. OBJECTIVE:To calculate potential cost savings attributable to increases in breastfeeding rates from the National Health Service perspective. DESIGN AND SETTINGS:Cost savings focussed on where evidence of health benefit is strongest: reductions in gastrointestinal and lower respiratory tract infections, acute otitis media in infants, necrotising enterocolitis in preterm babies and breast cancer (BC) in women. Savings were estimated using a seven-step framework in which an incidence-based disease model determined the number of cases that could have been avoided if breastfeeding rates were increased. Point estimates of cost savings were subject to a deterministic sensitivity analysis. RESULTS:Treating the four acute diseases in children costs the UK at least £89 million annually. The 2009-2010 value of lifetime costs of treating maternal BC is estimated at £959 million. Supporting mothers who are exclusively breast feeding at 1 week to continue breast feeding until 4 months can be expected to reduce the incidence of three childhood infectious diseases and save at least £11 million annually. Doubling the proportion of mothers currently breast feeding for 7-18 months in their lifetime is likely to reduce the incidence of maternal BC and save at least £31 million at 2009-2010 value. CONCLUSIONS:The economic impact of low breastfeeding rates is substantial. Investing in services that support women who want to breast feed for longer is potentially cost saving.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Pokhrel S,Quigley MA,Fox-Rushby J,McCormick F,Williams A,Trueman P,Dodds R,Renfrew MJdoi
10.1136/archdischild-2014-306701subject
Has Abstractpub_date
2015-04-01 00:00:00pages
334-40issue
4eissn
0003-9888issn
1468-2044pii
archdischild-2014-306701journal_volume
100pub_type
杂志文章abstract::Standing height, sitting height, armspan, subischial leg length, head circumference, and growth hormone-insulin-like growth factor I (IGF-I) axis were determined in 86 patients with osteogenesis imperfecta. The aim of this study was to determine standing height and body proportions and their variability among osteogen...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.6.524
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVES:To assess bone and collagen turnover in asthmatic children treated with dry powder budesonide from the Turbuhaler and dry powder beclomethasone dipropionate from the Diskhaler in a dose of 800 micrograms/day. SUBJECTS:Thirteen prepubertal children with asthma. DESIGN:Open crossover study with two treatment...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.73.6.524
更新日期:1995-12-01 00:00:00
abstract::Infantile liver disease with deficiency of serum alpha1-antitrypsin is illustrated by a description of the clinical, biochemical, and pathological findings in two affected families. The simplicity of the diagnostic tests is emphasized. Review of 61 biopsies of liver from children and adolescents provided a further 3 c...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.8.584
更新日期:1976-08-01 00:00:00
abstract::Four children, including three infants, who died suddenly and unexpectedly are described. In three of the cases group A beta haemolytic streptococcus was cultured and in the fourth Streptococcus pneumoniae. The organism was grown from multiple sites including blood in two of them. Without microbiological investigation...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.69.3.381
更新日期:1993-09-01 00:00:00
abstract::A novel form of severe, X linked mental retardation associated with alpha thalassaemia (ATR-X syndrome) has recently been described. Two affected cousins are described, one of whom has an unusually mild haematological phenotype. HbH inclusions, which are the hallmark of this disease, were only detected in the peripher...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.70.5.439
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:To assess the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) for the treatment of chronic constipation in children. DESIGN:Randomised, double blind, placebo controlled crossover trial, with two 2-week treatment periods separated by a 2-week placebo washout. SETTING:Six UK paediat...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/adc.2006.115493
更新日期:2007-11-01 00:00:00
abstract:AIM:To identify the experiences of patients, parents or carers when a child/young person is prescribed a new long-term medicine. METHOD:Patients' prescribed a new long-term (>6 weeks) medicine were recruited from a single UK paediatric hospital out-patient pharmacy.A semi-structured questionnaire was administered to p...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2016-311535.58
更新日期:2016-09-01 00:00:00
abstract::Mortality from cystic fibrosis throughout childhood is more than twice as high in England and Wales than it is in the State of Victoria, Australia. Possible reasons for this difference are reviewed. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.1.71
更新日期:1984-01-01 00:00:00
abstract::A survey was carried out in 10 centres in England and Wales to determine the costs of hearing screening in the first year of life. The screens that were studied were targeted neonatal, universal neonatal, and the health visitor distraction test (HVDT) or alternative surveillance. Valid data were available from five ce...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.78.1.14
更新日期:1998-01-01 00:00:00
abstract::Seventy six children, 18 boys and 58 girls, aged 0-15.9 (median 1.0) years, with acute pyelonephritis were prospectively studied with a technetium-99m dimercaptosuccinic acid (DMSA) scan during infection and two months later. Fifty nine of these children were also studied two years after the infection. Seventeen child...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.70.2.111
更新日期:1994-02-01 00:00:00
abstract::Psychotropic medication use by children in the USA has increased. We used the IMS MIDAS Prescribing Insights to examine prescribing trends in nine countries between the years 2000 and 2002. Trends in seven countries rose significantly from year 2000 to 2002; the UK had the highest increase (68%). ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2004.050468
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of depression in children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) and investigate the relationship between depression in CFS/ME and clinical symptoms such as fatigue, disability, pain and school attendance. DESIGN:Cross-sectional survey data using the Hos...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2012-303396
更新日期:2013-06-01 00:00:00
abstract::A 14-month-old girl with invasive perineal amoebiasis is reported. There was destruction of the anus, the rectovaginal septum, the pelvic floor, and the perineum. The rapid progress and destructive potential of perineal amoebiasis is noted and the benefits of diagnostic awareness emphasised. Treatment with metronidazo...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.3.234
更新日期:1980-03-01 00:00:00
abstract:BACKGROUND:Growth hormone insufficiency (GHI) is diagnosed conventionally by short stature and slow growth, and is confirmed by diminished peak GH response to a provocation test. Insulin-like growth factor I (IGF-I) and IGF binding protein 3 (IGFBP-3) have previously been considered individually OBJECTIVE:To test the ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.5.443
更新日期:1999-05-01 00:00:00
abstract::A 20-year-old woman with untreated homocystinuria was examined when she was 18 weeks' pregnant. Amniocentesis was performed and raised levels of homocystine and methionine were present in the amniotic fluid. Assay of cystathionine synthetase activity in cultured amniotic fluid cells showed the carrier state for homocy...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.9.721
更新日期:1980-09-01 00:00:00
abstract:AIM:To measure drug adherence in children with mild asthma receiving long term prophylactic treatment. METHODS:Double blind randomised placebo controlled trial. Patients received inhaled budesonide 100 microg or 200 microg daily, or placebo for 27 months. All participants were asked to inhale medication or placebo fro...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.83.4.330
更新日期:2000-10-01 00:00:00
abstract::Paediatric gynaecology is an emerging discipline. Since 2000, there has been an advanced training programme in paediatric gynaecology available for obstetric and gynaecology trainees; additionally, a set of clinical standards 1 for the care of paediatric and adolescent patients has been developed by The British Societ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2017-314375
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To study the relation between traumatic birth and the development of permanent facial palsy in the newborn. DESIGN:Retrospective case control study of children with 'congenital' facial palsy. SETTING:Two tertiary referral centres for patients with facial palsy. SUBJECTS:61 children with established facial ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.74.1.56
更新日期:1996-01-01 00:00:00
abstract::Twice daily sustained release theophylline gave satisfactory steady serum theophylline concentrations in asthmatic children aged 7 to 14 years. The children showed improvement in symptoms, less frequent waking at night, reduced use of beta agonist inhalers, and improved early morning peak flows while being treated wit...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.59.12.1159
更新日期:1984-12-01 00:00:00
abstract::Data from the Glasgow Register of Congenital Malformations were used to investigate the epidemiology of congenital facial clefts over the period 1974-85. Facial clefts were registered in 247 infants representing a prevalence of 1.56 per 1000 total births. Cleft palate was more common than cleft lip, with cleft lip and...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.7.717
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:To study the effect of body composition on average daily metabolic rate (ADMR) and basal metabolic rate (BMR) in adolescence, and to examine current BMR prediction equations. STUDY:Dutch adolescents were pooled with previously reported American and British subjects (n = 90 overall). BMR and ADMR were analyse...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.85.1.73
更新日期:2001-07-01 00:00:00
abstract::Vision screening of 13 and 15 year old children by school nurses in Oxfordshire has declined in recent years due to the pressure of other commitments. A study was carried out to evaluate the likely consequences of failing to provide vision screening for secondary schoolchildren, in order to make a decision about the f...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.70.1.14
更新日期:1994-01-01 00:00:00
abstract::We identified 410 infants who were not walking independently by the age of 18 months from among a geographically defined population of 4275 infants who either were born weighing less than 2000 g or had needed admission to the special care nursery in the neonatal period. The outcome of the late walkers was ascertained ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.5.486
更新日期:1990-05-01 00:00:00
abstract::Three neonates with rectal perforations probably caused by the use of the rectal thermometer, are reported. The dangers of this condition and the difficulty of diagnosis even at laporatomy are emphasised. It is suggested that since the axillary temperature in the neonate is an adequate reflection of the core temperatu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.10.824
更新日期:1978-10-01 00:00:00
abstract:BACKGROUND:Neonatal autosomal-recessive polycystic kidney disease (ARPKD) is associated with pulmonary hypoplasia and severe respiratory distress. There is no published information on long-term lung function in ARPKD survivors. METHODS:Pulmonary function tests, including spirometry and diffusion capacity, were perform...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2015-308451
更新日期:2015-10-01 00:00:00
abstract::Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章
doi:10.1136/adc.55.3.171
更新日期:1980-03-01 00:00:00
abstract::Endotracheal intubation and intermittent positive pressure ventilation were used to overcome the difficulties of oxygen therapy for pneumatosis cystoides coli in a 9-year-old child with Down's syndrome and a congenital heart defect. As compared to previously reported cases, a shorter duration of treatment and a lower ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.12.956
更新日期:1977-12-01 00:00:00
abstract:OBJECTIVE:Use next-generation sequencing (NGS) technology to improve our diagnostic yield in patients with suspected genetic disorders in the Asian setting. DESIGN:A diagnostic study conducted between 2014 and 2019 (and ongoing) under the Singapore Undiagnosed Disease Program. Date of last analysis was 1 July 2019. S...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2020-319180
更新日期:2021-01-01 00:00:00
abstract::Over a 25 year period, 31 asthmatic children received artificial ventilation for acute asthma at Alder Hey Children's Hospital on 48 occasions. Altogether 47 episodes occurred from 1971-89, with no decline in the number of episodes per year (mean 2.5) over this period. Eight children died during intermittent positive ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.12.1324
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:To assess differences across educational outcomes in survivors of childhood cancer (CCS) compared with peers. DESIGN:Systematic review and meta-analysis of observational studies. DATA SOURCES AND STUDY SELECTION:Medline, EMBASE, ERIC, CINAHL and PsycInfo from inception to 1st August 2018. Any peer reviewed,...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/archdischild-2019-317594
更新日期:2020-04-01 00:00:00