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Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids.

Abstract：

:Current biosynthetic methods for producing proteins containing site-specifically incorporated unnatural amino acids are inefficient because the majority of the amino acid goes unused. Here we present a universal approach to improve the efficiency of such processes using condensed Escherichia coli cultures.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Liu J,Castañeda CA,Wilkins BJ,Fushman D,Cropp TA

doi

10.1016/j.bmcl.2010.08.049

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

5613-6

issue

19

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(10)01172-8

journal_volume

20

pub_type

杂志文章

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