Evaluation of aqueous extract of Felicia muricata leaves for anti-inflammatory, antinociceptive, and antipyretic activities.

abstract：CONTEXT:Melatonin, a pineal hormone and a potent antioxidant, has important roles in metabolic regulation. OBJECTIVE:This study investigated serum asymmetric dimethylarginine (ADMA), homocysteine (Hcy), nitric oxide (NO) levels, known to be reliable markers of cardiovascular diseases, and determined possible protectiv...

journal_title：Pharmaceutical biology

authors： Kantar Ş,Türközkan N,Bircan FS,Paşaoğlu ÖT

更新日期：2015-07-01 00:00:00

abstract：CONTEXT:Growing adipose tissue is thought to require adipogenesis, angiogenesis, and extracellular matrix (ECM) remodeling. Close examination of developing adipose tissue microvasculature reveals that angiogenesis often precedes adipogenesis. Since our previous study demonstrated that Ob-X, the anti-angiogenic herbal c...

journal_title：Pharmaceutical biology

authors： Hong Y,Kim MY,Yoon M

更新日期：2011-08-01 00:00:00

abstract：:Context: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle.Objective: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism.Materials and methods: Cytotoxicity ...

journal_title：Pharmaceutical biology

authors： Cao WQ,Zhai XQ,Ma JW,Fu XQ,Zhao BS,Zhang P,Fu XY

更新日期：2020-12-01 00:00:00

abstract：UNLABELLED:CONTEXT. Huperzia saururus (Lam.) Trevis. (Lycopodiaceae), an autochthonous plant species in Argentina, is used as a memory improver in traditional medicine. It was studied for this reason and the purified alkaloid extract did show significant activity on learning and memory. The species is mostly consumed i...

journal_title：Pharmaceutical biology

authors： Vallejo MG,Dimmer JA,Ortega MG,Cabrera JL,Agnese AM

更新日期：2013-10-01 00:00:00

abstract：:Context Diabetes is a global health challenge. Although large prospective clinical trials have shown that intensive control of blood glucose or blood pressure reduces the risk for development and progression of vascular complications in diabetes, a substantial number of diabetic patients still experience renal failure...

journal_title：Pharmaceutical biology

authors： Yamagishi S,Matsui T

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:The fruit of the Prunus mume Sieb. et Zucc (Rosaceae) is used as a health food or medicinal material in traditional herb medicine for a long time in Eastern Asian countries. OBJECTIVE:Our present study investigated the hypouricemic effect of the methanol extract from P. mume fruit (MPMF) in mice with potassium...

journal_title：Pharmaceutical biology

authors： Yi LT,Li J,Su DX,Dong JF,Li CF

更新日期：2012-11-01 00:00:00

abstract：CONTEXT:Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in Chinese Pharmacopoeia, European Pharmacopoeia, and British Pharmacopoeia. OBJECTIVE:This review comprehensively summarizes research progress in ...

journal_title：Pharmaceutical biology

authors： Wang ZL,Wang S,Kuang Y,Hu ZM,Qiao X,Ye M

更新日期：2018-12-01 00:00:00

abstract：CONTEXT: Despite the myriad uses of Annona senegalensis Pers. (Annonaceae) leaves in folklore medicine of Nigeria, the basis is yet to be substantiated by scientific investigations. OBJECTIVES: To investigate the antioxidant (in vitro and in vivo) and drug detoxification potential of aqueous extract of A. senegalensis...

journal_title：Pharmaceutical biology

authors： Ajboye TO,Yakubu MT,Salau AK,Oladiji AT,Akanji MA,Okogun JI

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:Solenostemon monostachyus P. Beauv (Lamiaceae) is an important herb used traditionally in the treatment of malaria, fever, and other diseases. OBJECTIVES:Antiplasmodial and antipyretic activities of S. monostachyus aerial extract were evaluated to ascertain the folkloric claim of its antimalarial and antipyret...

journal_title：Pharmaceutical biology

authors： Okokon J,Davis KA,Azare BA

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Despite phytochemical studies of Agrimonia pilosa Ledeb. (Rosaceae), the antidiabetic effects of this plant are unknown. OBJECTIVE:This study characterizes the isolated compounds from the aerial parts of A. pilosa and evaluates their PTP1B and α-glucosidase inhibitory properties. MATERIALS AND METHODS:Ethanol...

journal_title：Pharmaceutical biology

authors： Na B,Nguyen PH,Zhao BT,Vo QH,Min BS,Woo MH

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. OBJECTIVE:This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. MATERIALS AND METHODS:The pharmacokinetics of orally administered anastrozole (...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wu J,Zhou Y,Yin Y,Chen H

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Glycyrrhiza glabra L. (Febaceae) has been widely used in traditional medicine and scientifically explored for its anticonvulsant and memory improving potential. OBJECTIVE:The objective of this study is to investigate the effect of flavonoid rich fraction of G. glabra root extract against phenytoin-induced cogn...

journal_title：Pharmaceutical biology

authors： Singh P,Singh D,Goel RK

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：CONTEXT:Plants and most of the plant-derived compounds have long been known for their potential pharmaceutical effects. They are well known to play an important role in the treatment of several diseases from diabetes to various types of cancers. Today most of the clinically effective pharmaceuticals are developed from ...

journal_title：Pharmaceutical biology

authors： Koc S,Isgor BS,Isgor YG,Shomali Moghaddam N,Yildirim O

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Augmented renal clearance (ARC) refers to enhanced renal elimination of circulating solute, and has attracted wide attention in recent years. OBJECTIVE:This study evaluates the effects of ARC on serum vancomycin concentration in patients administered vancomycin. MATERIALS AND METHODS:This was a retrospective ...

journal_title：Pharmaceutical biology

authors： Chu Y,Luo Y,Qu L,Zhao C,Jiang M

更新日期：2016-12-01 00:00:00

abstract：:Context: Emodin is a compound in Rheum undulatum Linne (Polygonaceae) that has been reported to exert anti-inflammatory, antibacterial, and antiallergic effects.Objective: Oxidative stress is a causative agent of liver inflammation that may lead to fibrosis and hepato-carcinoma. In this study, we investigated the anti...

journal_title：Pharmaceutical biology

authors： Lee EH,Baek SY,Park JY,Kim YW

更新日期：2020-12-01 00:00:00

abstract：:Context: Fuzheng Huayu recipe (FZHY) combined with entecavir (ETV) is used to treat the cirrhosis caused by chronic hepatitis B (CHB) infection.Objective: To investigate the effect of FZHY on ETV pharmacokinetics under different conditions.Materials and methods: A model of liver fibrosis was created by intraperitoneal...

journal_title：Pharmaceutical biology

authors： Yang T,Zheng TH,Zhao Q,Liu W,Li SP,Tao YY,Wang CH,Liu CH

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Polygonum species have been used in the treatment of several types of inflammatory disorders and cancer. Nevertheless, there are no reports related to the anti-inflammatory and anti-proliferative activities of Polygonum bellardii All. (Polygonaceae). OBJECTIVE:This study investigated the chemical composition o...

journal_title：Pharmaceutical biology

authors： Abd El-Kader AM,El-Readi MZ,Ahmed AS,Nafady AM,Wink M,Ibraheim ZZ

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Hippocratea africana (Willd.) Loes. ex Engl. (Celastraceae) root is used traditionally as an antipoison or antidote to treat liver diseases. OBJECTIVE:To evaluate antioxidative burst and hepatoprotective potentials of H. africana against paracetamol-induced liver injury in rats. MATERIALS AND METHOD:Antioxida...

journal_title：Pharmaceutical biology

authors： Okokon JE,Nwafor PA,Charles U,Dar A,Choudhary MI

更新日期：2013-07-01 00:00:00

abstract：:Context 3,4-Oxo-isopropylidene-shikimic acid (ISA) is an analog of shikimic acid (SA). SA is extracted from the dry fruit of Illicium verum Hook. f. (Magnoliaceae), which has been used for treating stomachaches, skin inflammation and rheumatic pain. Objective To investigate the anti-inflammatory, analgesic and antioxi...

journal_title：Pharmaceutical biology

authors： Sun JY,You CY,Dong K,You HS,Xing JF

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Angelica sinensis (Oliv.) Diels (Apiaceae) (syn. Angelica polymorpha Maxim var. sinensis Oliver) processed with yellow rice wine (WAS) has a blood-supplementing effect. OBJECTIVE:To establish an optimal technology for preparing water decoction of WAS (WASD), and screen blood-supplementing fractions. MATERIALS...

journal_title：Pharmaceutical biology

authors： Ji P,Li C,Wei Y,Wu F,Liu S,Hua Y,Yao W,Zhang X,Yuan Z,Wen Y

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Dexamethasone (DXM) has an anti-immunoinflammatory effect, and is often used in acute kidney injury (AKI). However, the effects of DXM on albumin (ALB) have not been fully studied. OBJECTIVE:To investigate the effects of DXM on ALB production and renal function. MATERIALS AND METHODS:Male Wistar rats were div...

journal_title：Pharmaceutical biology

authors： Gong Q,Yin J,Wang M,He L,Lei F,Luo Y,Yang S,Feng Y,Li J,Du L

更新日期：2020-12-01 00:00:00

abstract：:Rhinacanthus nasutus (L.) Kurz (Acanthaceae) has long been used in Thai traditional medicine for treatment of tinea versicolor, ringworm, pruritic rash, and abscess. The active constituents are known as a group of naphthoquinone esters, rhinacanthins. This work focused on establishment of R. nasutus root cultures and ...

journal_title：Pharmaceutical biology

authors： Panichayupakaranant P,Meerungrueang W

更新日期：2010-11-01 00:00:00

abstract：:Abstract Context: Galbanic acid (GA) is a biologically active sesquiterpene coumarin from Ferula species (Apiaceae). This compound showed various biological properties including anticancer, cancer chemopreventive, anticoagulant, antiviral, and antileishmanial activities. Objectives: This article is a review on the syn...

journal_title：Pharmaceutical biology

authors： Kasaian J,Iranshahy M,Iranshahi M

更新日期：2013-12-13 00:00:00

abstract：CONTEXT:Cyclophosphamide (CP) causes lung injury in rats through its ability to generate free radicals with subsequent epithelial and endothelial cell damage. OBJECTIVE:This study was conducted to assess whether allicin can ameliorate CP-induced early lung injury in rats. MATERIALS AND METHODS:Male Sprague Dawely rat...

journal_title：Pharmaceutical biology

authors： Ashry NA,Gameil NM,Suddek GM

更新日期：2013-06-01 00:00:00

abstract：CONTEXT:The bacterium Pseudomonas syringae pv. syringae (Pss) is a pathogen of many plant species and causes, for example, brown spot disease in bean plants (Phaseolus vulgaris). Pss excretes the syringolins, natural product molecules that act as a virulence factors and inhibit the proteasome of the host plants. OBJEC...

journal_title：Pharmaceutical biology

authors： Opoku-Ansah J,Ibarra-Rivera TR,Pirrung MC,Bachmann AS

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:Cancer dramatically impacts human life expectancy and quality of life. Natural substances from vegetables, herbs and spices could be beneficial in the prevention or treatment of a variety of cancers. Crocus sativus (Iridaceae), which has been used as a folk medicine for treating diseases for ages, showed obviou...

journal_title：Pharmaceutical biology

authors： Zhang Z,Wang CZ,Wen XD,Shoyama Y,Yuan CS

更新日期：2013-07-01 00:00:00

abstract：CONTEXT:Salvicine is a pharmacologically active derivative from Chinese medicinal plant Salvia prionitis Hance (Labiatae). It has been reported that salvicine inactivates β1 integrin and inhibits integrin-mediated cell adhesion to fibronectin. Given the emerging correlation between integrins and angiogenesis, we propos...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wang L,Chen Y,Qing C

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Silymarin (SM) is extracted from milk thistle Silybum marianum L. [Asteraceae (Compositae)] and known for antioxidative and anti-inflammatory effects. OBJECTIVE:The potential antidepressant-like effect of acute SM and possible involvement of nitric oxide (NO) were determined in male mice. MATERIAL AND METHODS...

journal_title：Pharmaceutical biology

authors： Khoshnoodi M,Fakhraei N,Dehpour AR

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:The nephron-protective efficacy of Abelmoschus manihot (Linn.) Medicus (Malvaceae) has been proved by randomized controlled clinical trial. OBJECTIVE:Flavonoids are main active components of A. manihot, which can be transformed into glucuronide/sulfate conjugates in vivo. Exploring the pharmacokinetic profile ...

journal_title：Pharmaceutical biology

authors： Guo J,Du L,Shang E,Li T,Liu Y,Qian D,Tang Y,Duan J

更新日期：2016-01-01 00:00:00