Abstract:
:Pooled analyses may provide etiologic insight about associations between exposure and disease. In contrast to childhood leukemia, no pooled analyses of childhood brain tumors and exposure to extremely low-frequency magnetic fields (ELF-MFs) have been conducted. The authors carried out a pooled analysis based on primary data (1960-2001) from 10 studies of ELF-MF exposure and childhood brain tumors to assess whether the combined results, adjusted for potential confounding, indicated an association. The odds ratios for childhood brain tumors in ELF-MF exposure categories of 0.1-<0.2 μT, 0.2-<0.4 μT, and ≥0.4 μT were 0.95 (95% confidence interval: 0.65, 1.41), 0.70 (95% CI: 0.40, 1.22), and 1.14 (95% CI: 0.61, 2.13), respectively, in comparison with exposure of <0.1 μT. Other analyses employing alternate cutpoints, further adjustment for confounders, exclusion of particular studies, stratification by type of measurement or type of residence, and a nonparametric estimate of the exposure-response relation did not reveal consistent evidence of increased childhood brain tumor risk associated with ELF-MF exposure. These results provide little evidence for an association between ELF-MF exposure and childhood brain tumors.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Kheifets L,Ahlbom A,Crespi CM,Feychting M,Johansen C,Monroe J,Murphy MF,Oksuzyan S,Preston-Martin S,Roman E,Saito T,Savitz D,Schüz J,Simpson J,Swanson J,Tynes T,Verkasalo P,Mezei Gdoi
10.1093/aje/kwq181subject
Has Abstractpub_date
2010-10-01 00:00:00pages
752-61issue
7eissn
0002-9262issn
1476-6256pii
kwq181journal_volume
172pub_type
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