Abstract：
:The authors investigated the relations of body mass index at different ages and adult weight change to incident colorectal cancer risk in the prospective National Institutes of Health-AARP Diet and Health Study (1995-1996), using a subcohort with repeated recall weights (273,679 participants; mean baseline age = 62.8 years). During 2,509,662 person-years follow-up, 4076 incident colorectal cancers were ascertained. For men, an increased risk of colon cancer but not rectal cancer was associated with body mass index at baseline age (per 5-kg/m(2) increase, hazard ratio (HR) = 1.18, 95% confidence interval (CI): 1.11, 1.25), at age 50 years (HR = 1.18, 95% CI: 1.10, 1.26), and at age 35 years (HR = 1.16, 95% CI: 1.07, 1.25) but less so at age 18 years. Weight gained between the ages of 18 and 35 years and between 18 years of age and the baseline age was associated with an increased risk of colon cancer in men (per 0.5-kg/year increase, HR = 1.18, 95% CI: 1.11, 1.25 and HR = 1.29, 95% CI: 1.16, 1.56, respectively). For women, relations throughout were weaker than those observed for men. These findings suggest that weight gains during early to middle adulthood have important influences on colon cancer risk, especially in men.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Renehan AG,Flood A,Adams KF,Olden M,Hollenbeck AR,Cross AJ,Leitzmann MFdoi
10.1093/aje/kws192subject
Has Abstractpub_date
2012-12-15 00:00:00pages
1130-40issue
12eissn
0002-9262issn
1476-6256pii
kws192journal_volume
176pub_type
杂志文章abstract：:A cohort of 3,916 Swedish copper smelter workers employed for at least 3 months between 1928 and 1967 was followed up through 1981. Arsenic exposure was estimated for different time periods at each workplace within the smelter. Detailed job records were linked to the exposure matrix, thus forming individual cumulative...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116128
更新日期：1991-09-15 00:00:00
abstract：:The first naturally acquired case of cholera reported in the United States since 1911 occurred in a 51-year-old resident of Port Lavaca, Texas. Extensive epidemiologic investigation of the patient's contacts and environment did not identify a cholera carrier of elucidate a pathway of transmission, but several avenues ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112061
更新日期：1974-12-01 00:00:00
abstract：:Familial resemblance in the blood pressure response to sodium restriction in normotensive persons was investigated. Forty-four families of identical twin children participated in a sodium restriction (less than or equal to 75 meq/day) protocol for a period of 12 weeks. Subjects were residents of central Indiana, and t...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114719
更新日期：1987-11-01 00:00:00
abstract：:For determination of the effects of weight variability on cardiovascular risk factors, a random community sample of 269 men and 361 women aged 25-74 years, drawn from the Stanford Five-City Project, was followed for up to 10 years (1979-1989). Systolic and diastolic blood pressure, total and high density lipoprotein c...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117448
更新日期：1995-03-01 00:00:00
abstract：:Outbreaks of respiratory tract illnesses (RTI) in adult humans during October and November 1975 at McMurdo Station, Antarctica, were investigated by viral isolation and serologic procedures. The recovery of viral agents was enhanced by use of cell cultures in the field. Recoveries of parainfluenzaviruses types 1 and 3...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112857
更新日期：1979-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114410
更新日期：1986-09-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113445
更新日期：1982-10-01 00:00:00
abstract：:This study investigated blood pressure in 1,183 Chinese nuclear families (mother, father, and first two children) via a cross-sectional 1994-1997 survey. The mother's, the father's, and the first sibling's blood pressures were each significantly and independently related to the second sibling's blood pressure after ad...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009828
更新日期：1999-03-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008667
更新日期：1996-05-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2020-09-05 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2004-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009188
更新日期：1997-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117541
更新日期：1995-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a010103
更新日期：1999-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/154.7.657
更新日期：2001-10-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwj049
更新日期：2006-02-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1093/aje/kwi222
更新日期：2005-09-01 00:00:00
abstract：:A prevalence study was designed to evaluate host and seasonal risk factors associated with three systemic mycoses in dogs: blastomycosis, coccidioidomycosis, and histoplasmosis. Histoplasmosis was the most commonly diagnosed of the three diseases. All three of the mycoses occurred more frequently in male than female d...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113077
更新日期：1981-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1985-09-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
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更新日期：2008-12-01 00:00:00
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更新日期：2003-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114476
更新日期：1986-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2003-11-15 00:00:00
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journal_title：American journal of epidemiology
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更新日期：2007-07-01 00:00:00
abstract：:Plague (infection by Yersinia pestis) was present in Hawaii for the period 1899-1957 and caused at least 370 fatalities. The first infections came from immigrant commensal rats, probably Rattus rattus and Rattus norvegicus, on ships from the Orient. Both species were already established in Hawaii and became the widesp...
journal_title：American journal of epidemiology
pub_type： 历史文章,杂志文章
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更新日期：1984-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：1976-12-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2004-04-01 00:00:00
abstract：:The authors examined associations between exposure to aluminum or silica from drinking water and risk of cognitive decline, dementia, and Alzheimer's disease among elderly subjects followed for 15 years (1988-2003). They actively searched for incident cases of dementia among persons aged 65 years or over living in 91 ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn348
更新日期：2009-02-15 00:00:00
