Abstract:
:Acral lentiginous melanoma (ALM) is the most frequent type of cutaneous melanoma in the Asian and African populations, but the fourth distinct variant of cutaneous melanoma in the Caucasian population. Histological criteria and prognosis of ALM remain controversial. A retrospective study, showing epidemiological, clinical, histological and survival characteristics of melanomas located on acral sites (acral cutaneous melanoma) compared with nonacral melanomas. Fifty-two of 552 melanomas (9.42%) were located on acral sites. Histological examination revealed ALMs in 30 cases (61%), nodular melanomas in seven cases (14.3%) and superficial spreading melanomas in five cases (10.2%). Patients with ulcerated melanomas had an older mean age (62.3 vs. 57.2 years) (P=0.02). Tumour thickness was greater in acral melanomas (2.8 vs. 1.9 mm) (P=0.039). Overall survival and disease-free survival did not differ significantly from melanomas on other sites. Acral cutaneous melanoma has peculiar epidemiological features in the Spanish population. They are more frequent in patients above 65 years of age and they have a greater tumour thickness, but they are not significantly associated with a lower survival.
journal_name
Melanoma Resjournal_title
Melanoma researchauthors
Avilés-Izquierdo JA,Longo-Imedio MI,Lázaro-Ochaita Pdoi
10.1097/CMR.0b013e3282f1d2b6subject
Has Abstractpub_date
2010-06-25 00:00:00eissn
0960-8931issn
1473-5636pub_type
杂志文章abstract::Large population-based studies have shown a significant association between melanoma and lymphoid neoplasia, particularly non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukaemia (CLL), that is independent of any treatment received for the initial tumour. This study examines the presentation, diagnosis, treatmen...
journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200110000-00012
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journal_title:Melanoma research
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200302000-00004
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journal_title:Melanoma research
pub_type: 杂志文章,评审
doi:10.1097/CMR.0b013e328322fc20
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journal_title:Melanoma research
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2014-06-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0b013e3282fe9a16
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journal_title:Melanoma research
pub_type: 杂志文章,评审
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journal_title:Melanoma research
pub_type: 杂志文章
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更新日期:2001-12-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章,评审
doi:10.1097/00008390-200010000-00001
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200204000-00006
更新日期:2002-04-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199804000-00010
更新日期:1998-04-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
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更新日期:2016-02-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200212000-00010
更新日期:2002-12-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200108000-00002
更新日期:2001-08-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0000000000000512
更新日期:2019-02-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0000000000000195
更新日期:2015-12-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200010000-00011
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pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199806000-00001
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199412000-00009
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0b013e328303beac
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199802000-00002
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