Abstract：
STUDY OBJECTIVE:To evaluate the influence of nasal oxygen (O(2)) administration on the duration of arterial oxygen saturation (SpO(2)) >or=95% during simulated difficult laryngoscopy in obese patients. DESIGN:Prospective, randomized, controlled trial. SETTING:University hospital. PATIENTS:30 obese men undergoing general anesthesia. INTERVENTIONS:After thorough preoxygenation, and using total intravenous anesthesia, simulated difficult laryngoscopy was performed, with half the patients receiving additional nasal O(2) during apnea. MEASUREMENTS:Duration of SpO(2) >or=95% was measured up to a maximum of 6 minutes. Lowest SpO(2) values and time to regain 100% SpO(2) (resaturation time) also were recorded. MAIN RESULTS:Nasal O(2) administration was associated with significant prolongation of SpO(2) >or=95% time (5.29 +/- 1.02 vs. 3.49 +/- 1.33 min, mean +/- SD), a significant increase in patients with SpO(2) >or=95% apnea at 6 minutes (8 vs. one pt), and significantly higher minimum SpO(2) (94.3 +/- 4.4% vs. 87.7 +/- 9.3%). Resaturation times were no different between the groups. CONCLUSIONS:Nasal O(2) administration is associated with significant increases in frequency and duration of SpO(2) >or=95%, and higher minimum SpO(2) during prolonged laryngoscopy in obese patients.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Ramachandran SK,Cosnowski A,Shanks A,Turner CRdoi
10.1016/j.jclinane.2009.05.006subject
Has Abstractpub_date
2010-05-01 00:00:00pages
164-8issue
3eissn
0952-8180issn
1873-4529pii
S0952-8180(10)00004-8journal_volume
22pub_type
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journal_title：Journal of clinical anesthesia
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