Abstract:
BACKGROUND:A microsporidian was previously reported to infect the crustacean parasite, Lepeophtheirus salmonis (Krøyer, 1837) (Copepoda, Caligidae), on farmed Atlantic salmon (Salmo salar L.) in Scotland. The microsporidian was shown to be a novel species with a molecular phylogenetic relationship to Nucleospora (Enterocytozoonidae), but the original report did not assign it to a genus or species. Further studies examined the development of the microsporidian in L. salmonis using electron microscopy and re-evaluated the molecular findings using new sequence data available for the group. Here we report a full description for the microsporidian and assign it to a new genus and species. RESULTS:The microsporidian infects subcuticular cells that lie on the innermost region of the epidermal tissue layer beneath the cuticle and along the internal haemocoelic divisions. The mature spores are sub-spherical with a single nucleus and an isofilar polar filament with 5-8 turns in a double coil. The entire development is in direct contact with the host cell cytoplasm and is polysporous. During early merogony, a diplokaryotic nuclear arrangement exists which is absent throughout the rest of the developmental cycle. Large merogonial plasmodia form which divide to form single uninucleate sporonts. Sporogonial plasmodia were not observed; instead, binucleate sporonts divide to form two sporoblasts. Prior to final division, there is a precocious development of the polar filament extrusion apparatus which is associated with large electron lucent inclusions (ELIs). Analyses of DNA sequences reveal that the microsporidian is robustly supported in a clade with other members of the Enterocytozoonidae and confirms a close phylogenetic relationship with Nucleospora. CONCLUSION:The ultrastructural findings of the precocious development of the polar filament and the presence of ELIs are consistent with those of the Enterocytozoonidae. However, the confirmed presence of an early diplokaryotic stage and a merogonial plasmodium that divides to yield uninucleate sporonts instead of transforming into a sporogonial syncitium, are features not currently associated with the family. Yet, analyses of DNA sequence data clearly place the microsporidian within the Enterocytozoonidae. Therefore, due to the novelty of the copepod host, the ultrastructural findings and the robust nature of the phylogenetic analyses, a new genus should be created within the Enterocytozoonide; Desmozoon lepeophtherii n. gen. n. sp. is proposed.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Freeman MA,Sommerville Cdoi
10.1186/1756-3305-2-58subject
Has Abstractpub_date
2009-11-27 00:00:00pages
58issue
1issn
1756-3305pii
1756-3305-2-58journal_volume
2pub_type
杂志文章abstract:BACKGROUND:Practical, field-ready age-grading tools for mosquito vectors of disease are urgently needed because of the impact that daily survival has on vectorial capacity. Previous studies have shown that near-infrared spectroscopy (NIRS), in combination with chemometrics and predictive modeling, can forecast the age ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04031-3
更新日期:2020-03-30 00:00:00
abstract:BACKGROUND:West African Dwarf (WAD) goats serve an important role in the rural village economy of West Africa, especially among small-holder livestock owners. They have been shown to be trypanotolerant and to resist infections with Haemonchus contortus more effectively than any other known breed of goat. METHODS:In th...
journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-4-12
更新日期:2011-02-03 00:00:00
abstract:BACKGROUND:Canine filarioids are important nematodes transmitted to dogs by arthropods. Diagnosis of canine filariosis is accomplished by the microscopic identification of microfilariae, serology or PCR for filarial-DNA. The aim of this study was to evaluate a molecular assay for the detection of canine filariae in dog...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0783-8
更新日期:2015-03-23 00:00:00
abstract:BACKGROUND:Knowledge of the potential vector role of Culicidae mosquitoes in Germany is very scanty, and until recently it was generally assumed that they are not involved in the transmission of anthroponotic or zoonotic pathogens in this country. However, anticipated changes in the course of global warming and globali...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-14
更新日期:2012-01-11 00:00:00
abstract:BACKGROUND:Malaria vector control in Africa relies on insecticides targeting adult mosquito vectors via insecticide treated nets or indoor residual spraying. Despite the proven efficacy of these strategies, the emergence and rapid rise in insecticide resistance in malaria vectors raises many concerns about their sustai...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1354-3
更新日期:2016-02-05 00:00:00
abstract:BACKGROUND:The East Asian mosquito species Aedes koreicus was recorded out of its native range for the first time in Belgium in 2008. Since then, several other European populations or single individuals have been observed throughout Europe with reports from Italy, Switzerland, European Russia, Slovenia, Germany and Hun...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3199-4
更新日期:2018-12-17 00:00:00
abstract:BACKGROUND:In this study for the first time, a Dientamoeba fragilis protein profile by MALDI-TOF MS was created in order to identify specific markers for the application of this technology in the laboratory diagnosis of dientamoebiasis. In particular, one D. fragilis reference strain was used to create a reference spec...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2597-3
更新日期:2018-01-04 00:00:00
abstract:BACKGROUND:Alternative splicing (AS) of mRNA is a vital mechanism for enhancing genomic complexity in eukaryotes. Spliced isoforms of the same gene can have diverse molecular and biological functions and are often differentially expressed across various tissues, times, and conditions. Thus, AS has important implication...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-151
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. It is one of the neglected tropical diseases identified by the World Health Organization for elimination as a public health problem by 2020. Maps displaying disease distribution are helpful tools to ide...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3097-9
更新日期:2018-09-17 00:00:00
abstract:BACKGROUND:Gastrointestinal nematodes are parasites that commonly infect dogs, and infections can be subclinical or may cause considerable clinical disease. Some species are zoonotic and may also cause clinical disease in humans. Year-round treatment of dogs is recommended to eliminate existing infections, which also i...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-3947-0
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Human and animal fascioliasis poses serious public health problems in South America. In Venezuela, livestock infection represents an important veterinary problem whereas there appear to be few human cases reported, most of which are passively detected in health centres. However, results of recent surveys sug...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-200
更新日期:2011-10-14 00:00:00
abstract:BACKGROUND:In Morocco, the main strategies of leishmaniasis vector control are based on environmental modifications. Use of local residual indoor spraying with synthetic pyrethroids is often envisaged. The need to evaluate this control method is essential. The current study was conducted to determine the efficacy of an...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-354
更新日期:2013-12-13 00:00:00
abstract:BACKGROUND:Understanding local Anopheles species compositions and bionomic traits are vital for an effective malaria vector intervention strategy. Though eight malaria vectors, including species complexes, have been documented across the island of Sulawesi, Indonesia, a comprehensive survey linking morphological and mo...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04252-6
更新日期:2020-07-29 00:00:00
abstract::Ticks (Acari: Ixodida) are arthropod ectoparasites dependent on a bloodmeal from a vertebrate host at each developmental stage for completion of their life cycle. This tick feeding cycle impacts animal health by causing damage to hides, secondary infections, immune reactions and diseases caused by transmission of path...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1185-7
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:In the final phase of China's national programme to eliminate malaria by 2020, it is vitally important to monitor the resistance of malaria vectors for developing effective vector control strategies. In 2017 Shanghai declared that it had eliminated malaria; however, the insecticide resistance status of the p...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3657-7
更新日期:2019-08-09 00:00:00
abstract:BACKGROUND:There is a continuing need for novel approaches to tick control in dogs. One such approach lies in the ability of lotilaner (Credelio™), an isoxazoline with a rapid onset of action, to provide sustained efficacy against ticks. Two studies were undertaken to confirm lotilaner's efficacy, at the minimum dose r...
journal_title:Parasites & vectors
pub_type: 杂志文章,随机对照试验
doi:10.1186/s13071-017-2477-x
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:The water buffalo (Bubalus bubalis) is well adapted in some regions of the Amazon. Of all Brazilian states, Pará contains the largest number of this species, with 510,000 animals, approximately 38% of the Brazilian buffaloes. Despite the socioeconomic importance of bubaline farming in the northern region, li...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2917-2
更新日期:2018-06-04 00:00:00
abstract:BACKGROUND:The preventive effect of fluralaner spot-on solution against transmission of Babesia canis by Dermacentor reticulatus ticks was evaluated. FINDINGS:Sixteen dogs, tested negative for B. canis by polymerase chain reaction (PCR) and immunofluorescence assay test (IFAT), were allocated to two study groups. On d...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1481-x
更新日期:2016-05-31 00:00:00
abstract:BACKGROUND:Hard ticks are hematophagous ectoparasites characterized by their long-term feeding. The saliva that they secrete during their blood meal is their crucial weapon against host-defense systems including hemostasis, inflammation and immunity. The anti-hemostatic, anti-inflammatory and immune-modulatory activiti...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2874-9
更新日期:2018-05-24 00:00:00
abstract:BACKGROUND:Despite similarities in morphology, gene and protein profiles, Entamoeba histolytica and E. moshkovskii show profound differences in pathogenicity. Entamoeba histolytica infection might result in amoebic dysentery and liver abscess, while E. moshkovskii causes only mild diarrhea. Extensive studies focus on r...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3363-5
更新日期:2019-03-13 00:00:00
abstract:BACKGROUND:The frequent outbreaks of human trichinellosis globally underscore the need to develop effective vaccine. We hypothesized that a novel vaccine could improve vaccine efficacy against Trichinella spiralis. METHODS:In this study, we developed virus-like particles (VLPs) containing the 53 KDa excretory/secretor...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1662-7
更新日期:2016-07-04 00:00:00
abstract:BACKGROUND:Adult fleas are haematophagous ectoparasites of warm-blooded vertebrates, particularly mammals. Among them, the cat flea (Ctenocephalides felis) and the human flea (Pulex irritans) have high veterinary-medical significance, owing to their cosmopolitan distribution and role in the transmission of important ve...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2798-4
更新日期:2018-04-02 00:00:00
abstract::An amendment to this paper has been published and can be accessed via the original article. ...
journal_title:Parasites & vectors
pub_type: 已发布勘误
doi:10.1186/s13071-020-04349-y
更新日期:2020-09-22 00:00:00
abstract:BACKGROUND:Chhattisgarh state in central India is highly endemic for malaria and contributes about 13% of annually reported malaria cases in the country with predominance of P. falciparum. Entomological investigations were carried out in a tribal forested area of district Bastar located in the southern part of Chhattis...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-215
更新日期:2012-09-28 00:00:00
abstract:BACKGROUND:Humans are parasitized by three types of lice: body, head and pubic lice. As their common names imply, each type colonizes a specific region of the body. The body louse is the only recognized disease vector. However, an increasing awareness of head lice as a vector has emerged recently whereas the status of ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04036-y
更新日期:2020-04-07 00:00:00
abstract:BACKGROUND:The trypanosome diversity of the Brush-tailed Bettong (Bettongia penicillata), known locally as the woylie, has been further investigated. At a species level, woylies are critically endangered and have declined by 90% since 1999. The predation of individuals made more vulnerable by disease is thought to be t...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-121
更新日期:2013-04-26 00:00:00
abstract:BACKGROUND:Cutaneous Leishmaniasis (CL) is endemic in Sudan. It is caused by Leishmania major parasites and transmitted by Phlebotomus papatasi sandflies. Recently, uncommon clinical manifestations of CL have been reported. Moreover, L. donovani parasites that cause Visceral Leishmaniasis (VL) have been isolated from C...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-249
更新日期:2012-11-12 00:00:00
abstract:BACKGROUND:Cyclospora is a protistan parasite that causes enteritis in several species of animals including humans. The aim of this study was to investigate the presence of Cyclospora in captive non-human primates. METHODS:A total of 119 faecal samples from Pan troglodytes, Macaca sylvanus, Cercopithecus cephus, Eryth...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0872-8
更新日期:2015-05-15 00:00:00
abstract::Since 2004 there has been an increased recognition of the importance of Neglected Tropical Diseases (NTDs) as impediments to development. These diseases are caused by a variety of infectious agents - viruses, bacteria and parasites - which cause a diversity of clinical conditions throughout the tropics. The World Heal...
journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-4-234
更新日期:2011-12-13 00:00:00
abstract:BACKGROUND:The red fox (Vulpes vulpes) is host to a community of zoonotic and other helminth species. Tracking their community structure and dynamics over decades is one way to monitor the long term risk of parasitic infectious diseases relevant to public and veterinary health. METHODS:We identified 17 helminth specie...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-166
更新日期:2014-04-03 00:00:00